ENSG00000147140

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000276079 ENSG00000147140 No_inf pgwt_inf NONO protein_coding protein_coding 165.5095 148.0393 165.2093 6.179283 2.271508 0.1583048 104.206915 101.253983 90.34976 3.0415415 1.5603891 -0.1643687 0.63110833 0.68585 0.547175 -0.138675 9.774314e-01 2.242772e-08 FALSE TRUE
ENST00000373841 ENSG00000147140 No_inf pgwt_inf NONO protein_coding protein_coding 165.5095 148.0393 165.2093 6.179283 2.271508 0.1583048 11.597111 8.357674 13.12478 1.9582201 3.3619898 0.6504934 0.06960833 0.05765 0.079100 0.021450 9.928472e-01 2.242772e-08 FALSE TRUE
ENST00000454976 ENSG00000147140 No_inf pgwt_inf NONO protein_coding protein_coding 165.5095 148.0393 165.2093 6.179283 2.271508 0.1583048 14.105062 0.000000 24.59493 0.0000000 3.8270171 11.2647314 0.08191667 0.00000 0.148575 0.148575 2.242772e-08 2.242772e-08 FALSE TRUE
ENST00000473525 ENSG00000147140 No_inf pgwt_inf NONO protein_coding retained_intron 165.5095 148.0393 165.2093 6.179283 2.271508 0.1583048 10.118034 13.327736 9.13057 0.9664588 0.7852589 -0.5451578 0.06290833 0.09025 0.055175 -0.035075 9.928472e-01 2.242772e-08 TRUE TRUE
ENST00000474431 ENSG00000147140 No_inf pgwt_inf NONO protein_coding protein_coding_CDS_not_defined 165.5095 148.0393 165.2093 6.179283 2.271508 0.1583048 4.110379 8.108120 0.00000 5.2297693 0.0000000 -9.6650019 0.02465833 0.05135 0.000000 -0.051350 9.764772e-01 2.242772e-08 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000147140 E001 0.0000000       X 71254814 71255000 187 +      
ENSG00000147140 E002 0.2630299 3.062644e-01 2.823328e-01   X 71266029 71266727 699 + 0.000 0.179 10.531
ENSG00000147140 E003 0.3429450 2.994205e-02 1.223375e-01   X 71283192 71283589 398 + 0.232 0.000 -14.223
ENSG00000147140 E004 0.1139502 1.123342e-02 5.842065e-01   X 71283590 71283609 20 + 0.092 0.000 -12.973
ENSG00000147140 E005 0.3431399 3.093918e-02 1.223956e-01   X 71283610 71283612 3 + 0.232 0.000 -14.211
ENSG00000147140 E006 0.3431399 3.093918e-02 1.223956e-01   X 71283613 71283614 2 + 0.232 0.000 -14.211
ENSG00000147140 E007 0.5893965 1.829970e-01 2.657489e-01   X 71283615 71283624 10 + 0.288 0.099 -1.879
ENSG00000147140 E008 1.0978844 1.972027e-01 9.459901e-01 0.9864310263 X 71283625 71283632 8 + 0.337 0.306 -0.202
ENSG00000147140 E009 1.0978844 1.972027e-01 9.459901e-01 0.9864310263 X 71283633 71283634 2 + 0.337 0.306 -0.202
ENSG00000147140 E010 1.5880187 8.401241e-02 9.216981e-01 0.9778390988 X 71283635 71283640 6 + 0.422 0.403 -0.102
ENSG00000147140 E011 1.8511955 9.628939e-02 7.147865e-01 0.8941599534 X 71283641 71283643 3 + 0.422 0.483 0.314
ENSG00000147140 E012 2.8670262 7.033625e-02 3.013427e-01 0.6287417727 X 71283644 71283647 4 + 0.493 0.660 0.759
ENSG00000147140 E013 4.2597495 6.790478e-02 1.162308e-01 0.3942891057 X 71283648 71283649 2 + 0.582 0.821 0.996
ENSG00000147140 E014 5.0126945 4.908904e-02 7.345314e-02 0.3077949381 X 71283650 71283651 2 + 0.632 0.883 1.014
ENSG00000147140 E015 5.7502381 5.569294e-02 1.098762e-01 0.3827163379 X 71283652 71283653 2 + 0.698 0.925 0.892
ENSG00000147140 E016 10.1960517 1.992423e-02 6.905339e-01 0.8820276013 X 71283654 71283662 9 + 1.026 1.069 0.156
ENSG00000147140 E017 24.4167489 3.848865e-03 6.344791e-01 0.8544004117 X 71283663 71283671 9 + 1.389 1.420 0.107
ENSG00000147140 E018 29.5713412 1.147661e-02 6.665182e-01 0.8706096003 X 71283672 71283675 4 + 1.468 1.500 0.109
ENSG00000147140 E019 42.7263709 7.612015e-03 9.648072e-01 0.9921647847 X 71283676 71283693 18 + 1.638 1.642 0.014
ENSG00000147140 E020 56.3589622 3.240400e-04 7.881872e-01 0.9265910197 X 71283694 71283721 28 + 1.764 1.753 -0.036
ENSG00000147140 E021 0.3928752 3.288065e-02 9.025018e-02   X 71283722 71283725 4 + 0.000 0.247 13.534
ENSG00000147140 E022 0.3928752 3.288065e-02 9.025018e-02   X 71283726 71283735 10 + 0.000 0.247 13.534
ENSG00000147140 E023 0.5071112 3.198891e-02 2.852322e-01   X 71283761 71283988 228 + 0.092 0.247 1.706
ENSG00000147140 E024 0.0000000       X 71284194 71284231 38 +      
ENSG00000147140 E025 51.3949937 3.319055e-04 5.138532e-01 0.7891460039 X 71284397 71284401 5 + 1.733 1.706 -0.092
ENSG00000147140 E026 53.0620326 3.063676e-04 3.673255e-01 0.6861067536 X 71284402 71284406 5 + 1.751 1.714 -0.125
ENSG00000147140 E027 67.0738130 1.184394e-03 1.081257e-01 0.3797022942 X 71284407 71284453 47 + 1.864 1.801 -0.210
ENSG00000147140 E028 4.6299921 1.749200e-02 7.174272e-01 0.8959569476 X 71284984 71285097 114 + 0.773 0.728 -0.184
ENSG00000147140 E029 1.1658564 4.286581e-02 1.279708e-02 0.1088939769 X 71285365 71286213 849 + 0.092 0.483 3.121
ENSG00000147140 E030 0.0000000       X 71288427 71288534 108 +      
ENSG00000147140 E031 34.4527487 3.986016e-04 4.347696e-02 0.2291064246 X 71290629 71290643 15 + 1.599 1.497 -0.350
ENSG00000147140 E032 128.9325721 7.206713e-04 3.270321e-01 0.6513760542 X 71290644 71290791 148 + 2.127 2.100 -0.093
ENSG00000147140 E033 0.4736711 2.982275e-02 3.651139e-01   X 71290792 71290795 4 + 0.232 0.099 -1.464
ENSG00000147140 E034 0.7016522 1.432499e-01 1.563633e-01 0.4578414003 X 71290796 71290806 11 + 0.337 0.099 -2.201
ENSG00000147140 E035 8.5867973 1.607038e-03 1.837800e-04 0.0047941744 X 71290807 71291778 972 + 0.756 1.122 1.384
ENSG00000147140 E036 49.2483534 3.074134e-04 7.394909e-01 0.9058660816 X 71291779 71291784 6 + 1.693 1.708 0.049
ENSG00000147140 E037 52.6039781 2.664778e-04 5.377309e-01 0.8035500361 X 71291785 71291868 84 + 1.716 1.741 0.087
ENSG00000147140 E038 61.5519306 2.320041e-04 1.315369e-02 0.1108024144 X 71291869 71291972 104 + 1.842 1.747 -0.321
ENSG00000147140 E039 4.7777719 2.936148e-03 9.218471e-01 0.9778438378 X 71291995 71293041 1047 + 0.756 0.767 0.047
ENSG00000147140 E040 3.3569929 8.687716e-02 3.299923e-01 0.6538129563 X 71294018 71294218 201 + 0.554 0.706 0.661
ENSG00000147140 E041 0.8172307 1.336695e-02 6.344567e-02 0.2840805384 X 71294219 71294226 8 + 0.382 0.099 -2.464
ENSG00000147140 E042 145.6300040 1.860310e-04 4.530201e-02 0.2339392988 X 71294227 71294348 122 + 2.191 2.141 -0.167
ENSG00000147140 E043 69.9932678 2.406334e-04 5.407196e-01 0.8053357486 X 71294349 71294397 49 + 1.839 1.862 0.076
ENSG00000147140 E044 129.1247982 2.355649e-04 2.460024e-01 0.5726108793 X 71294398 71294528 131 + 2.130 2.099 -0.103
ENSG00000147140 E045 0.3931610 3.266189e-02 9.022776e-02   X 71294529 71295154 626 + 0.000 0.247 13.536
ENSG00000147140 E046 118.8217350 5.653134e-03 3.801762e-01 0.6966047278 X 71296565 71296660 96 + 2.097 2.060 -0.123
ENSG00000147140 E047 0.8339259 4.949992e-02 3.155932e-01 0.6416114293 X 71296661 71296850 190 + 0.337 0.179 -1.201
ENSG00000147140 E048 192.2430009 1.782297e-04 6.636319e-01 0.8690410658 X 71296851 71297047 197 + 2.281 2.291 0.033
ENSG00000147140 E049 1.2284734 2.011998e-01 9.949638e-01 1.0000000000 X 71297048 71297360 313 + 0.337 0.357 0.122
ENSG00000147140 E050 0.2284008 1.539476e-02 2.721664e-01   X 71297361 71297376 16 + 0.167 0.000 -13.875
ENSG00000147140 E051 171.6152729 1.002721e-04 3.502717e-01 0.6707738437 X 71297377 71297461 85 + 2.248 2.227 -0.070
ENSG00000147140 E052 5.4859718 1.245159e-02 9.270740e-02 0.3497594351 X 71297462 71297587 126 + 0.698 0.897 0.788
ENSG00000147140 E053 3.3420846 1.883932e-02 4.567799e-01 0.7524834692 X 71297588 71297677 90 + 0.582 0.684 0.443
ENSG00000147140 E054 5.8733440 1.103876e-02 9.985298e-01 1.0000000000 X 71297678 71297835 158 + 0.837 0.837 0.001
ENSG00000147140 E055 100.2351778 1.552773e-04 1.798293e-02 0.1354809989 X 71297836 71297839 4 + 2.040 1.969 -0.238
ENSG00000147140 E056 97.5589733 1.543824e-04 6.712292e-02 0.2935084117 X 71297840 71297842 3 + 2.021 1.966 -0.186
ENSG00000147140 E057 216.3070982 8.883068e-05 5.039610e-03 0.0585410791 X 71297843 71297938 96 + 2.365 2.308 -0.189
ENSG00000147140 E058 54.6949394 2.727776e-04 1.934866e-06 0.0001008981 X 71297939 71298468 530 + 1.634 1.830 0.665
ENSG00000147140 E059 107.6354186 1.376623e-03 8.693732e-01 0.9585948284 X 71298469 71298477 9 + 2.038 2.033 -0.017
ENSG00000147140 E060 130.3842433 1.489737e-04 8.615026e-01 0.9554637571 X 71298478 71298508 31 + 2.121 2.116 -0.014
ENSG00000147140 E061 3.0073676 5.149220e-03 2.355849e-01 0.5606658677 X 71298509 71298706 198 + 0.677 0.518 -0.709
ENSG00000147140 E062 134.4727289 1.277744e-04 6.790822e-01 0.8764242582 X 71298707 71298816 110 + 2.126 2.137 0.037
ENSG00000147140 E063 6.6945629 2.045213e-03 1.682629e-01 0.4750683497 X 71298817 71299660 844 + 0.806 0.950 0.552
ENSG00000147140 E064 0.8501166 1.642656e-02 7.907150e-01 0.9277482310 X 71299661 71299758 98 + 0.288 0.247 -0.294
ENSG00000147140 E065 1.6029106 1.632151e-02 6.777833e-01 0.8759355164 X 71299759 71299941 183 + 0.382 0.445 0.343
ENSG00000147140 E066 430.1507579 5.541522e-05 2.662552e-01 0.5944578279 X 71299942 71300518 577 + 2.626 2.642 0.053
ENSG00000147140 E067 582.1955650 1.291702e-04 1.627626e-05 0.0006501442 X 71300519 71301522 1004 + 2.738 2.791 0.176

Help

Please Click HERE to learn more details about the results from DEXseq.