ENSG00000149091

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000527211 ENSG00000149091 No_inf pgwt_inf DGKZ protein_coding retained_intron 165.5605 203.7105 166.3172 2.517318 8.036648 -0.2925672 8.511336 11.98619 8.159939 0.5604728 0.428377 -0.5541787 0.05017500 0.058800 0.049200 -0.009600 9.932366e-01 1.464713e-05 FALSE TRUE
ENST00000529660 ENSG00000149091 No_inf pgwt_inf DGKZ protein_coding protein_coding_CDS_not_defined 165.5605 203.7105 166.3172 2.517318 8.036648 -0.2925672 14.512205 20.15947 13.776095 1.9654443 2.974076 -0.5489591 0.08543333 0.099350 0.081200 -0.018150 9.928472e-01 1.464713e-05 FALSE FALSE
ENST00000529698 ENSG00000149091 No_inf pgwt_inf DGKZ protein_coding retained_intron 165.5605 203.7105 166.3172 2.517318 8.036648 -0.2925672 9.251724 14.87806 6.345104 1.6448718 1.688168 -1.2281681 0.05404167 0.072800 0.037775 -0.035025 9.716538e-01 1.464713e-05 FALSE TRUE
ENST00000534802 ENSG00000149091 No_inf pgwt_inf DGKZ protein_coding retained_intron 165.5605 203.7105 166.3172 2.517318 8.036648 -0.2925672 3.414674 10.24402 0.000000 1.9809451 0.000000 -10.0019741 0.01679167 0.050375 0.000000 -0.050375 1.464713e-05 1.464713e-05 FALSE TRUE
MSTRG.4692.5 ENSG00000149091 No_inf pgwt_inf DGKZ protein_coding   165.5605 203.7105 166.3172 2.517318 8.036648 -0.2925672 77.454152 77.29247 85.433015 3.6616250 1.656138 0.1444481 0.48256667 0.379400 0.518425 0.139025 9.928472e-01 1.464713e-05 FALSE TRUE
MSTRG.4692.6 ENSG00000149091 No_inf pgwt_inf DGKZ protein_coding   165.5605 203.7105 166.3172 2.517318 8.036648 -0.2925672 15.024387 17.44629 10.841137 3.8608358 4.294094 -0.6859008 0.09405833 0.085675 0.064075 -0.021600 9.928472e-01 1.464713e-05 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000149091 E001 0.0000000       11 46332905 46333487 583 +      
ENSG00000149091 E002 0.6570699 0.0342849934 4.003290e-02 2.187756e-01 11 46338598 46338890 293 + 0.000 0.320 10.778
ENSG00000149091 E003 0.0000000       11 46345267 46345381 115 +      
ENSG00000149091 E004 0.0000000       11 46345382 46345390 9 +      
ENSG00000149091 E005 0.3594154 0.2182568276 5.062409e-01   11 46345391 46345402 12 + 0.190 0.086 -1.330
ENSG00000149091 E006 0.4733656 0.4507219802 4.378375e-01   11 46345403 46345413 11 + 0.261 0.086 -1.915
ENSG00000149091 E007 1.7639013 0.0076907965 5.172672e-03 5.961713e-02 11 46345414 46345422 9 + 0.633 0.219 -2.331
ENSG00000149091 E008 4.4185922 0.0040784391 5.018180e-01 7.819741e-01 11 46345423 46345431 9 + 0.774 0.693 -0.331
ENSG00000149091 E009 4.5331870 0.0043380283 4.002729e-01 7.117681e-01 11 46345432 46345433 2 + 0.794 0.693 -0.409
ENSG00000149091 E010 5.0419686 0.0275645303 5.989569e-01 8.370790e-01 11 46345434 46345436 3 + 0.812 0.747 -0.260
ENSG00000149091 E011 83.8280417 0.0001745012 1.878984e-02 1.388471e-01 11 46345437 46345585 149 + 1.966 1.888 -0.263
ENSG00000149091 E012 4.4511683 0.0139756130 9.849177e-01 9.991898e-01 11 46345586 46345589 4 + 0.732 0.730 -0.009
ENSG00000149091 E013 0.6042216 0.2229739493 5.306396e-01   11 46347463 46347522 60 + 0.261 0.157 -0.916
ENSG00000149091 E014 1.0784593 0.0112950612 1.827195e-01 4.956487e-01 11 46347523 46347587 65 + 0.423 0.219 -1.331
ENSG00000149091 E015 3.0895050 0.0131401700 4.291955e-03 5.231750e-02 11 46347588 46347820 233 + 0.794 0.403 -1.771
ENSG00000149091 E016 0.1138060 0.0111846143 4.272481e-01   11 46361522 46361605 84 + 0.105 0.000 -12.593
ENSG00000149091 E017 0.1138060 0.0111846143 4.272481e-01   11 46361606 46361606 1 + 0.105 0.000 -12.593
ENSG00000149091 E018 0.9637207 0.0178154433 3.104471e-01 6.367265e-01 11 46361607 46361706 100 + 0.375 0.219 -1.068
ENSG00000149091 E019 1.9447936 0.0076150026 3.460883e-01 6.671916e-01 11 46361707 46361963 257 + 0.540 0.403 -0.693
ENSG00000149091 E020 5.2554535 0.0204706763 2.811895e-01 6.091502e-01 11 46366015 46366243 229 + 0.864 0.730 -0.533
ENSG00000149091 E021 9.4681057 0.0033374352 2.172657e-02 1.514724e-01 11 46366244 46366526 283 + 1.126 0.914 -0.778
ENSG00000149091 E022 18.8169079 0.0012841068 2.986248e-02 1.836302e-01 11 46366527 46366984 458 + 1.371 1.223 -0.518
ENSG00000149091 E023 41.5516411 0.0003932537 7.640873e-05 2.370680e-03 11 46367291 46367314 24 + 1.721 1.537 -0.628
ENSG00000149091 E024 96.0947912 0.0003974453 8.867842e-03 8.579520e-02 11 46367315 46367399 85 + 2.027 1.944 -0.279
ENSG00000149091 E025 61.3231921 0.0002990698 1.476660e-01 4.443638e-01 11 46367652 46367654 3 + 1.820 1.763 -0.192
ENSG00000149091 E026 115.6958896 0.0001763458 7.790785e-03 7.872118e-02 11 46367655 46367747 93 + 2.103 2.027 -0.254
ENSG00000149091 E027 2.4208989 0.0057754160 1.655743e-01 4.713722e-01 11 46367748 46368001 254 + 0.633 0.439 -0.916
ENSG00000149091 E028 40.0653164 0.0004040145 1.556623e-02 1.232598e-01 11 46368002 46368004 3 + 1.671 1.555 -0.393
ENSG00000149091 E029 87.9351922 0.0056458696 5.983716e-03 6.587548e-02 11 46368005 46368079 75 + 2.010 1.888 -0.411
ENSG00000149091 E030 11.1494605 0.0252608691 7.595219e-03 7.753842e-02 11 46368080 46368177 98 + 0.880 1.175 1.084
ENSG00000149091 E031 88.0297104 0.0003241182 4.755578e-16 1.112135e-13 11 46368178 46369363 1186 + 1.754 2.037 0.952
ENSG00000149091 E032 17.6308074 0.0007991579 8.711511e-06 3.772098e-04 11 46369364 46369493 130 + 1.037 1.371 1.186
ENSG00000149091 E033 82.6974200 0.0029175461 5.247965e-01 7.954423e-01 11 46369494 46369550 57 + 1.931 1.904 -0.089
ENSG00000149091 E034 19.2188882 0.0012065511 6.525840e-05 2.078169e-03 11 46369551 46369940 390 + 1.107 1.394 1.011
ENSG00000149091 E035 61.1333979 0.0058354707 3.858002e-01 7.006401e-01 11 46369941 46370009 69 + 1.813 1.767 -0.156
ENSG00000149091 E036 55.9355169 0.0014359425 8.962135e-02 3.436671e-01 11 46371313 46371384 72 + 1.790 1.717 -0.248
ENSG00000149091 E037 97.7824073 0.0003915889 2.807882e-02 1.774451e-01 11 46371487 46371603 117 + 2.027 1.958 -0.233
ENSG00000149091 E038 52.8062826 0.0010969063 4.426551e-01 7.425752e-01 11 46371704 46371724 21 + 1.743 1.709 -0.115
ENSG00000149091 E039 69.0560992 0.0002103061 4.499366e-01 7.477703e-01 11 46371725 46371775 51 + 1.822 1.849 0.092
ENSG00000149091 E040 84.0481845 0.0001658737 4.165292e-01 7.235560e-01 11 46372075 46372170 96 + 1.906 1.933 0.089
ENSG00000149091 E041 71.7936002 0.0018719410 1.963922e-01 5.132235e-01 11 46372428 46372510 83 + 1.824 1.875 0.173
ENSG00000149091 E042 2.2766840 0.0144480475 1.602149e-01 4.630491e-01 11 46372511 46372616 106 + 0.375 0.584 1.048
ENSG00000149091 E043 67.3610616 0.0010641801 7.363751e-01 9.042558e-01 11 46372617 46372677 61 + 1.820 1.833 0.043
ENSG00000149091 E044 1.2965026 0.0106665904 1.896320e-02 1.392751e-01 11 46372678 46372770 93 + 0.105 0.472 2.839
ENSG00000149091 E045 55.0447659 0.0015756908 5.975392e-02 2.748032e-01 11 46372771 46372843 73 + 1.788 1.706 -0.279
ENSG00000149091 E046 36.9213839 0.0070762446 7.564514e-01 9.134682e-01 11 46372844 46372884 41 + 1.584 1.563 -0.070
ENSG00000149091 E047 1.7007408 0.0386830900 3.691167e-01 6.875172e-01 11 46372885 46372897 13 + 0.505 0.364 -0.746
ENSG00000149091 E048 39.2546841 0.0045598245 2.661045e-01 5.943689e-01 11 46372961 46373101 141 + 1.634 1.571 -0.213
ENSG00000149091 E049 51.0772668 0.0015887341 9.287198e-01 9.801570e-01 11 46374157 46374235 79 + 1.712 1.708 -0.015
ENSG00000149091 E050 80.1138853 0.0011251849 4.025936e-01 7.133571e-01 11 46374399 46374428 30 + 1.884 1.914 0.101
ENSG00000149091 E051 73.3176532 0.0053244341 4.631563e-01 7.564444e-01 11 46374429 46374454 26 + 1.843 1.878 0.117
ENSG00000149091 E052 103.1880096 0.0002103701 6.852040e-01 8.799084e-01 11 46374604 46374666 63 + 2.018 2.005 -0.043
ENSG00000149091 E053 0.8664660 0.2019991460 9.777725e-01 9.968146e-01 11 46374667 46374765 99 + 0.261 0.273 0.084
ENSG00000149091 E054 114.7168148 0.0001425352 9.609220e-02 3.569235e-01 11 46374766 46374839 74 + 2.084 2.036 -0.160
ENSG00000149091 E055 119.9425351 0.0001392714 8.956657e-01 9.685714e-01 11 46374934 46375023 90 + 2.078 2.074 -0.014
ENSG00000149091 E056 60.9066687 0.0002970883 7.816954e-01 9.244899e-01 11 46375024 46375045 22 + 1.778 1.789 0.035
ENSG00000149091 E057 165.8582931 0.0007740702 9.853899e-01 9.993567e-01 11 46375432 46375631 200 + 2.215 2.215 0.000
ENSG00000149091 E058 131.8717085 0.0001400527 3.579360e-02 2.050298e-01 11 46375851 46375951 101 + 2.148 2.092 -0.188
ENSG00000149091 E059 113.1496897 0.0014369152 6.373626e-01 8.558170e-01 11 46376066 46376145 80 + 2.059 2.044 -0.053
ENSG00000149091 E060 119.6037541 0.0017046023 9.579361e-02 3.561984e-01 11 46376328 46376397 70 + 2.041 2.095 0.181
ENSG00000149091 E061 0.1139502 0.0112166584 4.272555e-01   11 46376520 46376523 4 + 0.105 0.000 -12.592
ENSG00000149091 E062 87.5392320 0.0003802191 6.896392e-01 8.816633e-01 11 46376524 46376564 41 + 1.932 1.945 0.043
ENSG00000149091 E063 5.7487086 0.0028022390 3.180466e-01 6.435609e-01 11 46376565 46377072 508 + 0.753 0.865 0.440
ENSG00000149091 E064 51.7054324 0.0017296016 9.810886e-01 9.980234e-01 11 46377073 46377147 75 + 1.714 1.715 0.002
ENSG00000149091 E065 36.3540353 0.0004026602 3.401216e-01 6.621569e-01 11 46377148 46377212 65 + 1.593 1.545 -0.164
ENSG00000149091 E066 99.4367588 0.0028677637 1.566582e-04 4.217221e-03 11 46377213 46377967 755 + 1.903 2.048 0.485
ENSG00000149091 E067 9.5742879 0.0292772034 5.553784e-01 8.138355e-01 11 46377968 46377969 2 + 0.978 1.043 0.239
ENSG00000149091 E068 27.1960780 0.0005032638 6.410883e-02 2.856310e-01 11 46377970 46378197 228 + 1.376 1.484 0.371
ENSG00000149091 E069 58.9988968 0.0063881684 3.029430e-01 6.298838e-01 11 46378198 46378229 32 + 1.802 1.748 -0.180
ENSG00000149091 E070 11.9435773 0.0116083528 3.537453e-04 8.058751e-03 11 46378230 46378456 227 + 0.864 1.217 1.295
ENSG00000149091 E071 114.0671175 0.0002210765 7.003338e-01 8.870048e-01 11 46378457 46378500 44 + 2.060 2.049 -0.039
ENSG00000149091 E072 96.2695545 0.0001581391 7.532742e-11 9.080230e-09 11 46378501 46378893 393 + 1.845 2.055 0.706
ENSG00000149091 E073 38.9160525 0.0004599297 2.436590e-06 1.237788e-04 11 46378894 46378990 97 + 1.437 1.677 0.819
ENSG00000149091 E074 177.0973034 0.0007459442 7.230664e-01 8.984132e-01 11 46378991 46379111 121 + 2.238 2.247 0.028
ENSG00000149091 E075 107.5641612 0.0013433746 2.841681e-01 6.118513e-01 11 46379203 46379236 34 + 2.049 2.014 -0.119
ENSG00000149091 E076 52.0546764 0.0002918899 3.197993e-05 1.140918e-03 11 46379237 46379453 217 + 1.602 1.782 0.612
ENSG00000149091 E077 15.0401077 0.0011232696 4.888145e-04 1.037553e-02 11 46379454 46379468 15 + 1.014 1.291 0.991
ENSG00000149091 E078 178.4230681 0.0011499558 4.580759e-01 7.530944e-01 11 46379469 46379568 100 + 2.235 2.254 0.064
ENSG00000149091 E079 417.3742011 0.0006061048 6.337316e-02 2.839250e-01 11 46379831 46380554 724 + 2.633 2.601 -0.108

Help

Please Click HERE to learn more details about the results from DEXseq.