ENSG00000149289

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000278590 ENSG00000149289 No_inf pgwt_inf ZC3H12C protein_coding protein_coding 16.94707 13.13802 18.20377 0.1520612 0.474489 0.4701841 5.6936278 8.1582947 3.7890616 0.96371737 2.3554508 -1.104392 0.36212500 0.623625 0.200775 -0.42285 0.7652334442 0.0001941144 FALSE TRUE
ENST00000453089 ENSG00000149289 No_inf pgwt_inf ZC3H12C protein_coding protein_coding 16.94707 13.13802 18.20377 0.1520612 0.474489 0.4701841 0.8856499 1.6203195 0.3909665 0.28500805 0.1048218 -2.023601 0.05920833 0.123375 0.021225 -0.10215 0.3621828453 0.0001941144 FALSE TRUE
MSTRG.5508.1 ENSG00000149289 No_inf pgwt_inf ZC3H12C protein_coding   16.94707 13.13802 18.20377 0.1520612 0.474489 0.4701841 8.2073662 0.6317778 12.8607151 0.09291406 1.5748150 4.325874 0.44318333 0.047925 0.711825 0.66390 0.0001941144 0.0001941144 FALSE TRUE
MSTRG.5508.2 ENSG00000149289 No_inf pgwt_inf ZC3H12C protein_coding   16.94707 13.13802 18.20377 0.1520612 0.474489 0.4701841 1.8442424 2.7276288 1.1630285 1.02189593 0.6040389 -1.222689 0.11855000 0.205075 0.066175 -0.13890 0.9928472467 0.0001941144 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000149289 E001 5.4485557 2.571110e-03 1.797416e-06 9.484853e-05 11 110088352 110088601 250 + 0.993 0.384 -2.636
ENSG00000149289 E002 2.6518496 5.763558e-02 1.930097e-02 1.407820e-01 11 110092939 110093223 285 + 0.355 0.722 1.756
ENSG00000149289 E003 0.1141751 1.118598e-02 7.265480e-01   11 110093392 110093432 41 + 0.083 0.000 -8.790
ENSG00000149289 E004 0.1145948 1.124984e-02 7.264892e-01   11 110131004 110131106 103 + 0.083 0.000 -8.788
ENSG00000149289 E005 4.9662773 3.311993e-03 1.542718e-05 6.199601e-04 11 110135854 110136662 809 + 0.462 0.979 2.171
ENSG00000149289 E006 40.5504854 1.597936e-03 1.089207e-01 3.808802e-01 11 110136663 110137414 752 + 1.651 1.573 -0.266
ENSG00000149289 E007 10.7088686 1.358351e-03 2.095117e-01 5.304339e-01 11 110152919 110153058 140 + 1.114 1.005 -0.399
ENSG00000149289 E008 14.1094590 1.015006e-03 2.815953e-01 6.092446e-01 11 110159256 110159490 235 + 1.214 1.131 -0.296
ENSG00000149289 E009 6.4220464 1.287433e-01 7.283552e-01 9.008309e-01 11 110163273 110163379 107 + 0.877 0.861 -0.062
ENSG00000149289 E010 680.5253365 5.931296e-05 5.913772e-02 2.732025e-01 11 110164341 110171841 7501 + 2.829 2.836 0.024

Help

Please Click HERE to learn more details about the results from DEXseq.