ENSG00000149926

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000279389 ENSG00000149926 No_inf pgwt_inf TLCD3B protein_coding protein_coding 2.219747 2.7504 2.172615 0.7158336 0.564731 -0.3388199 0.4415568 0.0000000 0.84338876 0.0000000 0.12582636 6.4151312 0.22710833 0.000000 0.448600 0.448600 0.03953192 0.03953192 FALSE TRUE
ENST00000380495 ENSG00000149926 No_inf pgwt_inf TLCD3B protein_coding protein_coding 2.219747 2.7504 2.172615 0.7158336 0.564731 -0.3388199 0.2078032 0.6234095 0.00000000 0.1680671 0.00000000 -5.9850666 0.08271667 0.248150 0.000000 -0.248150 0.32911852 0.03953192 FALSE TRUE
ENST00000561666 ENSG00000149926 No_inf pgwt_inf TLCD3B protein_coding protein_coding 2.219747 2.7504 2.172615 0.7158336 0.564731 -0.3388199 0.5139610 0.5586275 0.48654239 0.2403907 0.33613355 -0.1955669 0.22245833 0.199400 0.200450 0.001050 1.00000000 0.03953192 FALSE FALSE
ENST00000564806 ENSG00000149926 No_inf pgwt_inf TLCD3B protein_coding protein_coding 2.219747 2.7504 2.172615 0.7158336 0.564731 -0.3388199 0.2426527 0.2949757 0.05569271 0.2949757 0.05569271 -2.2148889 0.15144167 0.141425 0.030975 -0.110450 1.00000000 0.03953192 FALSE TRUE
ENST00000567037 ENSG00000149926 No_inf pgwt_inf TLCD3B protein_coding protein_coding_CDS_not_defined 2.219747 2.7504 2.172615 0.7158336 0.564731 -0.3388199 0.2691834 0.5421882 0.20434310 0.1779967 0.09830143 -1.3652380 0.10888333 0.191475 0.084150 -0.107325 0.99284725 0.03953192 TRUE TRUE
ENST00000571269 ENSG00000149926 No_inf pgwt_inf TLCD3B protein_coding protein_coding 2.219747 2.7504 2.172615 0.7158336 0.564731 -0.3388199 0.5445897 0.7311995 0.58264795 0.5589213 0.23713183 -0.3226866 0.20741667 0.219600 0.235850 0.016250 0.99284725 0.03953192   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000149926 E001 0.0000000       16 30024427 30024451 25 -      
ENSG00000149926 E002 3.7150693 0.007492133 0.444972817 0.74412590 16 30024452 30025467 1016 - 0.693 0.641 -0.221
ENSG00000149926 E003 0.1145948 0.012460205 0.300632781   16 30025468 30025725 258 - 0.115 0.000 -11.545
ENSG00000149926 E004 0.9992797 0.012720374 0.996191830 1.00000000 16 30025726 30025821 96 - 0.280 0.299 0.129
ENSG00000149926 E005 0.0000000       16 30026603 30026608 6 -      
ENSG00000149926 E006 0.1138060 0.012401986 0.300628210   16 30026609 30026613 5 - 0.115 0.000 -11.545
ENSG00000149926 E007 1.6026195 0.207757336 0.557891447 0.81515538 16 30026614 30026843 230 - 0.449 0.378 -0.386
ENSG00000149926 E008 0.8679090 0.013456236 0.762097601 0.91555882 16 30029432 30029515 84 - 0.280 0.254 -0.193
ENSG00000149926 E009 0.1311489 0.013359389 1.000000000   16 30029516 30029536 21 - 0.000 0.079 9.962
ENSG00000149926 E010 0.2454580 0.018152839 0.675846315   16 30030060 30030084 25 - 0.115 0.079 -0.608
ENSG00000149926 E011 1.4445645 0.010524522 0.002559589 0.03633794 16 30030403 30031271 869 - 0.000 0.503 13.336
ENSG00000149926 E012 1.7889671 0.011014007 0.183655134 0.49686660 16 30032665 30033766 1102 - 0.280 0.503 1.267
ENSG00000149926 E013 0.2456120 0.017962738 0.671347246   16 30035161 30035306 146 - 0.115 0.079 -0.608
ENSG00000149926 E014 0.0000000       16 30035307 30035350 44 -      
ENSG00000149926 E015 0.6055552 0.370659942 0.518682777   16 30035351 30035422 72 - 0.280 0.145 -1.192
ENSG00000149926 E016 0.9824022 0.018056603 0.478980444 0.76688540 16 30035423 30035481 59 - 0.344 0.254 -0.608
ENSG00000149926 E017 0.0000000       16 30036155 30036214 60 -      
ENSG00000149926 E018 0.0000000       16 30036215 30036530 316 -      
ENSG00000149926 E019 1.1310378 0.013643721 0.785108377 0.92551485 16 30040995 30041156 162 - 0.280 0.340 0.392
ENSG00000149926 E020 0.8854866 0.014495057 0.615008272 0.84504540 16 30046323 30046387 65 - 0.205 0.299 0.714
ENSG00000149926 E021 0.0000000       16 30046566 30046631 66 -      
ENSG00000149926 E022 1.4913804 0.010520181 0.748528940 0.90981535 16 30052774 30052978 205 - 0.400 0.378 -0.122

Help

Please Click HERE to learn more details about the results from DEXseq.