ENSG00000151327

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000280987 ENSG00000151327 No_inf pgwt_inf FAM177A1 protein_coding protein_coding 23.91939 15.50133 27.54895 1.002653 2.657454 0.8291987 3.2694183 1.7994261 3.985998 0.6325123 0.3555181 1.1430238 0.13817500 0.123325 0.148625 0.025300 0.99284725 0.03267251 FALSE  
ENST00000382406 ENSG00000151327 No_inf pgwt_inf FAM177A1 protein_coding protein_coding 23.91939 15.50133 27.54895 1.002653 2.657454 0.8291987 9.5766516 4.0497560 12.472789 1.3500120 1.9301947 1.6204754 0.37262500 0.253500 0.449625 0.196125 0.99284725 0.03267251 FALSE  
ENST00000554052 ENSG00000151327 No_inf pgwt_inf FAM177A1 protein_coding protein_coding 23.91939 15.50133 27.54895 1.002653 2.657454 0.8291987 2.1214025 1.2391814 4.225688 0.7159690 1.5107777 1.7616132 0.09138333 0.083825 0.163975 0.080150 0.99284725 0.03267251    
ENST00000554794 ENSG00000151327 No_inf pgwt_inf FAM177A1 protein_coding protein_coding 23.91939 15.50133 27.54895 1.002653 2.657454 0.8291987 1.3247453 0.9032296 0.000000 0.9032296 0.0000000 -6.5129058 0.06275000 0.066425 0.000000 -0.066425 0.99284725 0.03267251 FALSE  
ENST00000556858 ENSG00000151327 No_inf pgwt_inf FAM177A1 protein_coding nonsense_mediated_decay 23.91939 15.50133 27.54895 1.002653 2.657454 0.8291987 1.1795538 1.2578114 1.097820 0.7332599 0.3770067 -0.1946170 0.05169167 0.075025 0.042125 -0.032900 0.99284725 0.03267251    
ENST00000699517 ENSG00000151327 No_inf pgwt_inf FAM177A1 protein_coding protein_coding_CDS_not_defined 23.91939 15.50133 27.54895 1.002653 2.657454 0.8291987 0.3500471 0.8208187 0.000000 0.1747588 0.0000000 -6.3764618 0.01979167 0.051700 0.000000 -0.051700 0.03267251 0.03267251    
MSTRG.8400.2 ENSG00000151327 No_inf pgwt_inf FAM177A1 protein_coding   23.91939 15.50133 27.54895 1.002653 2.657454 0.8291987 2.8700800 2.1564861 1.935965 0.7690706 1.9359655 -0.1548709 0.11569167 0.134450 0.058000 -0.076450 0.83746330 0.03267251    
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000151327 E001 0.5249031 0.0162623116 1.213305e-02   14 35045117 35045194 78 + 0.000 0.358 12.950
ENSG00000151327 E002 0.2450383 0.0161492199 6.887037e-01   14 35045988 35046130 143 + 0.074 0.121 0.778
ENSG00000151327 E003 0.0000000       14 35046233 35046243 11 +      
ENSG00000151327 E004 0.2283502 0.1603261495 5.163207e-01   14 35046244 35046271 28 + 0.138 0.000 -13.689
ENSG00000151327 E005 0.5708454 0.0157214204 7.466240e-02   14 35046272 35046285 14 + 0.287 0.000 -14.907
ENSG00000151327 E006 2.1393050 0.0069441458 3.884053e-01 7.022266e-01 14 35046286 35046377 92 + 0.535 0.415 -0.601
ENSG00000151327 E007 1.8311137 0.0082852250 4.735647e-01 7.634271e-01 14 35046378 35046406 29 + 0.397 0.511 0.585
ENSG00000151327 E008 1.5683184 0.0086835992 9.421083e-01 9.853693e-01 14 35046407 35046452 46 + 0.397 0.415 0.100
ENSG00000151327 E009 3.6910368 0.0043077168 3.224452e-01 6.470842e-01 14 35046453 35046504 52 + 0.709 0.589 -0.512
ENSG00000151327 E010 11.0301193 0.0012775021 4.402600e-01 7.408250e-01 14 35046505 35046592 88 + 1.094 1.039 -0.199
ENSG00000151327 E011 8.2505018 0.0017885855 3.278487e-01 6.520616e-01 14 35046593 35046603 11 + 0.991 0.906 -0.317
ENSG00000151327 E012 8.9357117 0.0015606684 1.331623e-01 4.228157e-01 14 35046604 35046628 25 + 1.038 0.906 -0.491
ENSG00000151327 E013 0.2283502 0.1603261495 5.163207e-01   14 35046629 35046680 52 + 0.138 0.000 -13.689
ENSG00000151327 E014 0.9293178 0.0509699811 1.335740e-01 4.234896e-01 14 35046681 35046954 274 + 0.363 0.121 -2.029
ENSG00000151327 E015 0.3589051 0.0168021992 1.000000e+00   14 35046955 35047084 130 + 0.138 0.121 -0.222
ENSG00000151327 E016 5.7859555 0.0025049663 9.948605e-01 1.000000e+00 14 35050033 35050396 364 + 0.820 0.831 0.041
ENSG00000151327 E017 0.1316618 0.0124128472 3.148726e-01   14 35050784 35050868 85 + 0.000 0.121 13.536
ENSG00000151327 E018 0.5069669 0.0193719317 1.341290e-01   14 35051141 35051262 122 + 0.074 0.293 2.363
ENSG00000151327 E019 0.0000000       14 35053200 35053277 78 +      
ENSG00000151327 E020 20.1894798 0.0007371375 2.567664e-03 3.639706e-02 14 35053278 35053451 174 + 1.384 1.197 -0.653
ENSG00000151327 E021 0.0000000       14 35054659 35054991 333 +      
ENSG00000151327 E022 11.9667364 0.0012312970 6.900694e-01 8.818332e-01 14 35077150 35077216 67 + 1.087 1.130 0.156
ENSG00000151327 E023 12.6193620 0.0012419273 6.238218e-01 8.493948e-01 14 35078927 35079024 98 + 1.137 1.109 -0.100
ENSG00000151327 E024 9.0401989 0.0015165992 9.804406e-01 9.976598e-01 14 35081022 35081080 59 + 0.991 0.999 0.031
ENSG00000151327 E025 26.7876169 0.0005525175 4.065828e-01 7.160250e-01 14 35081081 35081559 479 + 1.449 1.415 -0.117
ENSG00000151327 E026 29.0652410 0.0005780483 3.824073e-02 2.129272e-01 14 35081560 35083381 1822 + 1.419 1.536 0.402
ENSG00000151327 E027 0.0000000       14 35083438 35083510 73 +      
ENSG00000151327 E028 0.2458369 0.0162340390 6.884675e-01   14 35092094 35092211 118 + 0.074 0.121 0.778
ENSG00000151327 E029 0.0000000       14 35099652 35099675 24 +      
ENSG00000151327 E030 0.1145948 0.0115510830 1.000000e+00   14 35099676 35099695 20 + 0.074 0.000 -12.960
ENSG00000151327 E031 5.4509834 0.1394612065 7.642500e-02 3.145768e-01 14 35099696 35102680 2985 + 0.658 0.955 1.174
ENSG00000151327 E032 0.4557372 0.0159608824 1.334547e-01   14 35102681 35102729 49 + 0.243 0.000 -14.657
ENSG00000151327 E033 0.1138060 0.0112233732 1.000000e+00   14 35106363 35106366 4 + 0.074 0.000 -12.960
ENSG00000151327 E034 0.2279811 0.0152988286 4.737793e-01   14 35106367 35106415 49 + 0.138 0.000 -13.835
ENSG00000151327 E035 0.3769858 0.0166783174 3.150618e-01   14 35106416 35106484 69 + 0.074 0.215 1.778
ENSG00000151327 E036 0.0000000       14 35109895 35109960 66 +      
ENSG00000151327 E037 0.0000000       14 35110570 35110642 73 +      
ENSG00000151327 E038 0.0000000       14 35110643 35110726 84 +      
ENSG00000151327 E039 3.8524435 0.0060338810 3.163094e-07 1.987171e-05 14 35112864 35114363 1500 + 0.287 0.955 3.100
ENSG00000151327 E040 0.1138060 0.0112233732 1.000000e+00   14 35115188 35115305 118 + 0.074 0.000 -12.960
ENSG00000151327 E041 1.3130415 0.0099193068 2.344049e-05 8.775472e-04 14 35116277 35116630 354 + 0.000 0.624 16.335

Help

Please Click HERE to learn more details about the results from DEXseq.