ENSG00000152760

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000282670 ENSG00000152760 No_inf pgwt_inf DYNLT5 protein_coding protein_coding 50.38516 90.98065 35.63748 4.447029 16.47454 -1.351918 5.660051 6.010495 3.4680397 1.1723122 0.8331481 -0.7916077 0.17973333 0.068125 0.165675 0.097550 0.9928472467 0.0001479678 FALSE TRUE
ENST00000448074 ENSG00000152760 No_inf pgwt_inf DYNLT5 protein_coding protein_coding_CDS_not_defined 50.38516 90.98065 35.63748 4.447029 16.47454 -1.351918 3.003947 9.011840 0.0000000 3.1350634 0.0000000 -9.8172779 0.03142500 0.094275 0.000000 -0.094275 0.3768809216 0.0001479678   FALSE
MSTRG.1137.10 ENSG00000152760 No_inf pgwt_inf DYNLT5 protein_coding   50.38516 90.98065 35.63748 4.447029 16.47454 -1.351918 3.744305 7.347930 0.7686916 3.5841437 0.7686916 -3.2401758 0.07936667 0.077725 0.038600 -0.039125 0.9684825056 0.0001479678   FALSE
MSTRG.1137.11 ENSG00000152760 No_inf pgwt_inf DYNLT5 protein_coding   50.38516 90.98065 35.63748 4.447029 16.47454 -1.351918 1.884804 2.301473 0.5708070 2.3014732 0.5708070 -1.9926819 0.05500833 0.024725 0.028675 0.003950 0.9953548163 0.0001479678   FALSE
MSTRG.1137.16 ENSG00000152760 No_inf pgwt_inf DYNLT5 protein_coding   50.38516 90.98065 35.63748 4.447029 16.47454 -1.351918 3.967346 11.024952 0.8770846 0.8531648 0.8770846 -3.6368649 0.05599167 0.122400 0.045575 -0.076825 0.4399754859 0.0001479678 TRUE FALSE
MSTRG.1137.19 ENSG00000152760 No_inf pgwt_inf DYNLT5 protein_coding   50.38516 90.98065 35.63748 4.447029 16.47454 -1.351918 5.544307 0.000000 16.6329204 0.0000000 16.6329204 10.7006929 0.06519167 0.000000 0.195575 0.195575 0.9928472467 0.0001479678   FALSE
MSTRG.1137.2 ENSG00000152760 No_inf pgwt_inf DYNLT5 protein_coding   50.38516 90.98065 35.63748 4.447029 16.47454 -1.351918 6.440614 11.666962 4.5474051 4.3478833 0.6360860 -1.3573804 0.14672500 0.133600 0.176750 0.043150 0.9928472467 0.0001479678   FALSE
MSTRG.1137.22 ENSG00000152760 No_inf pgwt_inf DYNLT5 protein_coding   50.38516 90.98065 35.63748 4.447029 16.47454 -1.351918 3.882041 11.047505 0.0000000 0.8432836 0.0000000 -10.1108102 0.04920833 0.122950 0.000000 -0.122950 0.0001479678 0.0001479678   FALSE
MSTRG.1137.3 ENSG00000152760 No_inf pgwt_inf DYNLT5 protein_coding   50.38516 90.98065 35.63748 4.447029 16.47454 -1.351918 3.832815 9.742894 1.1104993 2.2572937 0.9811455 -3.1216886 0.06489167 0.108375 0.057950 -0.050425 0.9276193791 0.0001479678   FALSE
MSTRG.1137.6 ENSG00000152760 No_inf pgwt_inf DYNLT5 protein_coding   50.38516 90.98065 35.63748 4.447029 16.47454 -1.351918 5.289473 7.635441 5.0342526 1.8769305 0.2898929 -0.5999592 0.14166667 0.083200 0.210300 0.127100 0.9716538398 0.0001479678 TRUE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000152760 E001 0.5076187 3.390974e-02 7.058746e-01   1 66751719 66751765 47 + 0.181 0.130 -0.570
ENSG00000152760 E002 0.1308632 1.227576e-02 1.000000e+00   1 66752150 66752188 39 + 0.000 0.048 9.272
ENSG00000152760 E003 0.2625250 1.612735e-02 1.000000e+00   1 66752189 66752190 2 + 0.000 0.091 10.214
ENSG00000152760 E004 0.3936739 1.597144e-02 1.000000e+00   1 66752191 66752192 2 + 0.000 0.130 10.792
ENSG00000152760 E005 1.6900217 8.609003e-03 2.835791e-01 0.611233824 1 66752193 66752244 52 + 0.181 0.379 1.430
ENSG00000152760 E006 2.6889425 1.058405e-02 9.344539e-01 0.981866677 1 66752245 66752260 16 + 0.487 0.473 -0.068
ENSG00000152760 E007 4.5904502 3.500013e-03 5.618591e-01 0.817017916 1 66752261 66752271 11 + 0.710 0.628 -0.348
ENSG00000152760 E008 27.1052445 2.023675e-03 4.254484e-05 0.001454305 1 66752272 66752458 187 + 1.539 1.265 -0.949
ENSG00000152760 E009 14.6768043 9.896545e-04 1.557345e-02 0.123271466 1 66752459 66752494 36 + 1.244 1.031 -0.763
ENSG00000152760 E010 15.9774389 8.574959e-04 3.100385e-02 0.188034976 1 66752495 66752531 37 + 1.257 1.071 -0.660
ENSG00000152760 E011 22.3513965 6.734658e-04 2.940933e-02 0.182088140 1 66752532 66752584 53 + 1.375 1.213 -0.570
ENSG00000152760 E012 48.7398714 4.204977e-03 1.108261e-04 0.003209663 1 66754656 66754777 122 + 1.742 1.525 -0.740
ENSG00000152760 E013 5.4544869 3.739240e-02 2.937630e-01 0.622038570 1 66755644 66755679 36 + 0.825 0.673 -0.615
ENSG00000152760 E014 8.5012622 4.136378e-02 2.273300e-01 0.552110826 1 66755680 66755773 94 + 0.991 0.832 -0.599
ENSG00000152760 E015 0.1139502 1.124379e-02 8.535563e-02   1 66760685 66760737 53 + 0.181 0.000 -12.820
ENSG00000152760 E016 1.0347763 9.199159e-02 7.197713e-01 0.897135643 1 66767296 66767395 100 + 0.181 0.258 0.653
ENSG00000152760 E017 1.0495791 1.156676e-02 1.857250e-01 0.499589412 1 66768659 66768760 102 + 0.000 0.285 12.216
ENSG00000152760 E018 48.6047486 3.471642e-04 4.562334e-04 0.009849373 1 66770387 66770478 92 + 1.713 1.532 -0.615
ENSG00000152760 E019 20.5838916 7.814329e-04 3.638667e-01 0.683181219 1 66770479 66770578 100 + 1.144 1.222 0.278
ENSG00000152760 E020 16.2405066 2.396551e-03 2.316257e-01 0.557289319 1 66770579 66770645 67 + 1.013 1.131 0.430
ENSG00000152760 E021 119.5154146 1.325624e-04 8.140152e-01 0.936646961 1 66770646 66771747 1102 + 1.959 1.950 -0.030
ENSG00000152760 E022 238.0712783 3.288188e-04 9.510437e-01 0.987793321 1 66771748 66773424 1677 + 2.250 2.248 -0.007
ENSG00000152760 E023 26.3873110 5.390575e-04 2.209706e-01 0.544710889 1 66773425 66773507 83 + 1.231 1.326 0.333
ENSG00000152760 E024 55.7649481 2.554132e-04 2.726667e-01 0.600887787 1 66773508 66773832 325 + 1.576 1.635 0.199
ENSG00000152760 E025 37.1701446 3.748241e-04 9.710945e-01 0.994526784 1 66773833 66773975 143 + 1.453 1.455 0.006
ENSG00000152760 E026 202.6698179 8.954311e-05 8.271061e-01 0.941640444 1 66773976 66775045 1070 + 2.174 2.179 0.017
ENSG00000152760 E027 96.0330354 1.555768e-03 3.513849e-01 0.671650421 1 66775046 66775340 295 + 1.824 1.864 0.135
ENSG00000152760 E028 56.0051437 3.998097e-03 6.636268e-02 0.291487053 1 66775341 66775513 173 + 1.532 1.644 0.380
ENSG00000152760 E029 41.9571190 3.354277e-04 8.901485e-05 0.002677305 1 66775514 66775576 63 + 1.269 1.540 0.937
ENSG00000152760 E030 209.4321225 9.294849e-05 3.487980e-02 0.201570754 1 66775577 66776154 578 + 2.145 2.201 0.190
ENSG00000152760 E031 77.5334164 1.851669e-04 1.374261e-02 0.114348029 1 66776155 66776278 124 + 1.667 1.783 0.391
ENSG00000152760 E032 104.0474647 3.045434e-04 4.267700e-01 0.731011602 1 66776279 66776403 125 + 1.917 1.886 -0.104
ENSG00000152760 E033 591.0837752 6.551366e-05 8.375740e-01 0.945891287 1 66777251 66779646 2396 + 2.640 2.642 0.007

Help

Please Click HERE to learn more details about the results from DEXseq.