ENSG00000153531

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000375418 ENSG00000153531 No_inf pgwt_inf ADPRHL1 protein_coding protein_coding 4.206371 0.3261105 8.050844 0.05368568 0.3240849 4.583923 0.10259868 0.05787324 0.05132837 0.05787324 0.05132837 -0.1462883 0.0581000 0.121575 0.006625 -0.114950 0.68000892 0.00144413 FALSE TRUE
ENST00000612156 ENSG00000153531 No_inf pgwt_inf ADPRHL1 protein_coding protein_coding 4.206371 0.3261105 8.050844 0.05368568 0.3240849 4.583923 0.09878524 0.26823727 0.00000000 0.02112232 0.00000000 -4.7982438 0.2951500 0.878425 0.000000 -0.878425 0.00144413 0.00144413 FALSE TRUE
ENST00000682618 ENSG00000153531 No_inf pgwt_inf ADPRHL1 protein_coding protein_coding 4.206371 0.3261105 8.050844 0.05368568 0.3240849 4.583923 3.42887135 0.00000000 7.31733607 0.00000000 0.78034474 9.5171450 0.5373833 0.000000 0.902400 0.902400 0.04765654 0.00144413 FALSE TRUE
MSTRG.8088.3 ENSG00000153531 No_inf pgwt_inf ADPRHL1 protein_coding   4.206371 0.3261105 8.050844 0.05368568 0.3240849 4.583923 0.53371122 0.00000000 0.55496598 0.00000000 0.55496598 5.8200921 0.1044250 0.000000 0.076150 0.076150 0.99284725 0.00144413 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000153531 E001 0.6833492 0.018176260 1.0000000000 1.00000000 13 113399611 113399615 5 - 0.152 0.000 -29.412
ENSG00000153531 E002 169.4893246 0.245478098 0.0001614648 0.00431163 13 113399616 113408220 8605 - 2.007 1.558 -1.519
ENSG00000153531 E003 0.3422067 0.026745328 0.4822666418   13 113409355 113409375 21 - 0.083 0.000 -28.411
ENSG00000153531 E004 2.2186983 0.006527199 0.0278045165 0.17641097 13 113410856 113410975 120 - 0.326 0.553 1.198
ENSG00000153531 E005 0.1138060 0.011544423 0.1234572242   13 113421940 113421944 5 - 0.029 0.000 -26.826
ENSG00000153531 E006 0.9461542 0.365803520 0.0419795041 0.22474021 13 113421945 113422825 881 - 0.152 0.433 2.030
ENSG00000153531 E007 0.1315150 0.012530950 0.0026925678   13 113422826 113422979 154 - 0.000 0.269 33.850
ENSG00000153531 E008 0.1315150 0.012530950 0.0026925678   13 113424217 113424349 133 - 0.000 0.269 33.850
ENSG00000153531 E009 0.1308632 0.012589103 0.0026900649   13 113425052 113425179 128 - 0.000 0.269 33.850
ENSG00000153531 E010 0.2449549 0.016936878 0.0113596144   13 113428952 113429092 141 - 0.029 0.269 3.613
ENSG00000153531 E011 0.0000000       13 113433742 113433867 126 -      
ENSG00000153531 E012 0.3772587 0.017774605 0.0007545896   13 113444425 113444589 165 - 0.029 0.433 4.613
ENSG00000153531 E013 0.0000000       13 113448999 113449277 279 -      
ENSG00000153531 E014 0.1315150 0.012530950 0.0026925678   13 113453224 113453488 265 - 0.000 0.269 33.850

Help

Please Click HERE to learn more details about the results from DEXseq.