ENSG00000153561

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000283632 ENSG00000153561 No_inf pgwt_inf RMND5A protein_coding protein_coding 17.84764 26.81283 11.18335 0.6793957 0.5809388 -1.260819 14.028168 15.35440 11.18335 0.6990471 0.5809388 -0.4569492 0.857525 0.572575 1 0.427425 3.493286e-06 3.493286e-06 FALSE TRUE
ENST00000472843 ENSG00000153561 No_inf pgwt_inf RMND5A protein_coding protein_coding_CDS_not_defined 17.84764 26.81283 11.18335 0.6793957 0.5809388 -1.260819 3.819475 11.45843 0.00000 0.6140187 0.0000000 -10.1634517 0.142475 0.427425 0 -0.427425 3.493286e-06 3.493286e-06 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000153561 E001 13.95570 0.0091671864 1.808055e-05 0.0007073133 2 86720291 86720809 519 + 1.360 0.995 -1.304
ENSG00000153561 E002 12.89155 0.0015374266 2.318071e-01 0.5574680812 2 86740927 86741069 143 + 1.169 1.066 -0.368
ENSG00000153561 E003 0.00000       2 86748228 86748490 263 +      
ENSG00000153561 E004 16.93506 0.0009731017 3.551463e-01 0.6752371944 2 86751896 86752030 135 + 1.257 1.186 -0.251
ENSG00000153561 E005 15.99777 0.0010425390 1.251833e-01 0.4100883719 2 86753458 86753558 101 + 1.266 1.148 -0.417
ENSG00000153561 E006 23.80756 0.0056563600 2.341851e-02 0.1589769484 2 86765027 86765193 167 + 1.455 1.298 -0.542
ENSG00000153561 E007 0.00000       2 86765513 86765602 90 +      
ENSG00000153561 E008 22.88376 0.0007168732 5.491740e-01 0.8105213029 2 86765859 86766024 166 + 1.360 1.319 -0.143
ENSG00000153561 E009 19.44809 0.0009881576 7.554717e-01 0.9129290161 2 86770023 86770125 103 + 1.248 1.269 0.074
ENSG00000153561 E010 0.00000       2 86771301 86771450 150 +      
ENSG00000153561 E011 25.36241 0.0055622687 4.200562e-01 0.7261024709 2 86771558 86771712 155 + 1.413 1.358 -0.192
ENSG00000153561 E012 514.53837 0.0000715118 2.960471e-06 0.0001464820 2 86773348 86778041 4694 + 2.639 2.671 0.108

Help

Please Click HERE to learn more details about the results from DEXseq.