ENSG00000153827

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000470302 ENSG00000153827 No_inf pgwt_inf TRIP12 protein_coding retained_intron 88.50054 78.92429 92.1155 3.951912 2.722976 0.2229484 17.921729 16.514789 20.806195 2.859170 1.850709 0.33307451 0.20100000 0.205425 0.225725 0.020300 1.000000e+00 7.986996e-05 FALSE FALSE
ENST00000675903 ENSG00000153827 No_inf pgwt_inf TRIP12 protein_coding protein_coding 88.50054 78.92429 92.1155 3.951912 2.722976 0.2229484 3.181610 5.674989 1.841760 3.291614 1.841760 -1.61826037 0.03837500 0.072775 0.020550 -0.052225 9.928472e-01 7.986996e-05 FALSE TRUE
ENST00000704580 ENSG00000153827 No_inf pgwt_inf TRIP12 protein_coding protein_coding 88.50054 78.92429 92.1155 3.951912 2.722976 0.2229484 6.574825 0.000000 9.211767 0.000000 2.092909 9.84889943 0.07088333 0.000000 0.100475 0.100475 7.986996e-05 7.986996e-05 FALSE TRUE
ENST00000704582 ENSG00000153827 No_inf pgwt_inf TRIP12 protein_coding protein_coding 88.50054 78.92429 92.1155 3.951912 2.722976 0.2229484 36.048943 34.808403 35.779840 1.426654 1.356754 0.03970004 0.41084167 0.445700 0.388375 -0.057325 9.928472e-01 7.986996e-05 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000153827 E001 0.0000000       2 229763837 229763837 1 -      
ENSG00000153827 E002 2.0155540 0.0126853976 6.912167e-02 2.978714e-01 2 229763838 229763908 71 - 0.327 0.595 1.386
ENSG00000153827 E003 141.4812167 0.0001303924 1.935373e-38 2.014533e-35 2 229763909 229766415 2507 - 1.958 2.292 1.116
ENSG00000153827 E004 42.6813304 0.0003260329 1.046910e-07 7.341650e-06 2 229766416 229767120 705 - 1.502 1.748 0.837
ENSG00000153827 E005 14.3645938 0.0009749535 3.095772e-04 7.271777e-03 2 229767121 229767218 98 - 1.028 1.306 0.992
ENSG00000153827 E006 10.4662051 0.0170950800 1.849936e-02 1.376187e-01 2 229767219 229767223 5 - 0.925 1.165 0.876
ENSG00000153827 E007 12.1045360 0.0038826645 2.180609e-03 3.240756e-02 2 229767224 229767228 5 - 0.969 1.231 0.946
ENSG00000153827 E008 12.5956061 0.0018646674 1.906506e-03 2.931887e-02 2 229767229 229767231 3 - 0.990 1.244 0.917
ENSG00000153827 E009 16.1616747 0.0008407902 2.158242e-03 3.213813e-02 2 229767232 229767245 14 - 1.111 1.333 0.787
ENSG00000153827 E010 15.7512072 0.0010009028 8.455684e-03 8.292906e-02 2 229767246 229767252 7 - 1.118 1.311 0.683
ENSG00000153827 E011 52.2750236 0.0028602369 3.148723e-02 1.896881e-01 2 229767253 229767384 132 - 1.675 1.774 0.336
ENSG00000153827 E012 41.4165477 0.0003494241 2.488785e-01 5.758170e-01 2 229767385 229767425 41 - 1.601 1.653 0.180
ENSG00000153827 E013 38.3234726 0.0004466010 8.107955e-02 3.255570e-01 2 229767426 229767440 15 - 1.551 1.635 0.285
ENSG00000153827 E014 85.4828185 0.0001901529 6.314058e-01 8.527006e-01 2 229767441 229767553 113 - 1.930 1.944 0.050
ENSG00000153827 E015 136.9120297 0.0016359910 8.175717e-01 9.374605e-01 2 229767554 229767750 197 - 2.136 2.143 0.021
ENSG00000153827 E016 79.3965169 0.0023793679 5.930448e-01 8.340970e-01 2 229768616 229768719 104 - 1.916 1.894 -0.072
ENSG00000153827 E017 68.2208281 0.0004100366 1.903988e-01 5.049838e-01 2 229769231 229769325 95 - 1.816 1.864 0.160
ENSG00000153827 E018 82.0620222 0.0007798523 4.959168e-02 2.463620e-01 2 229771519 229771632 114 - 1.885 1.952 0.227
ENSG00000153827 E019 4.2935395 0.0077714773 4.406210e-03 5.326989e-02 2 229773561 229774096 536 - 0.511 0.869 1.511
ENSG00000153827 E020 98.1391399 0.0001569810 4.227272e-01 7.282458e-01 2 229774097 229774261 165 - 1.984 2.008 0.079
ENSG00000153827 E021 0.1316618 0.0122859562 4.520469e-01   2 229774917 229775085 169 - 0.000 0.103 10.249
ENSG00000153827 E022 90.8657879 0.0007836169 5.907400e-01 8.330019e-01 2 229777315 229777479 165 - 1.972 1.954 -0.062
ENSG00000153827 E023 71.4845421 0.0081009795 6.487546e-01 8.618134e-01 2 229778433 229778587 155 - 1.849 1.871 0.075
ENSG00000153827 E024 60.2310763 0.0026508864 2.167259e-01 5.397152e-01 2 229778876 229778990 115 - 1.813 1.758 -0.186
ENSG00000153827 E025 47.3467359 0.0002859912 1.826460e-01 4.955255e-01 2 229785757 229785855 99 - 1.712 1.653 -0.199
ENSG00000153827 E026 46.5393066 0.0003021951 6.829246e-01 8.786088e-01 2 229787505 229787661 157 - 1.668 1.686 0.059
ENSG00000153827 E027 48.1941856 0.0002850320 1.800203e-01 4.925124e-01 2 229788798 229788940 143 - 1.720 1.661 -0.199
ENSG00000153827 E028 57.1834461 0.0009132920 4.392932e-01 7.403366e-01 2 229789611 229789762 152 - 1.780 1.748 -0.110
ENSG00000153827 E029 51.7793302 0.0002865220 3.052699e-01 6.323134e-01 2 229791124 229791251 128 - 1.743 1.700 -0.147
ENSG00000153827 E030 0.0000000       2 229791788 229791865 78 -      
ENSG00000153827 E031 45.7323500 0.0003234489 9.776740e-01 9.967697e-01 2 229791866 229791973 108 - 1.671 1.669 -0.006
ENSG00000153827 E032 42.7249931 0.0003874855 5.717264e-01 8.227298e-01 2 229791974 229792065 92 - 1.654 1.627 -0.090
ENSG00000153827 E033 36.5899150 0.0058147281 9.971424e-01 1.000000e+00 2 229792153 229792226 74 - 1.575 1.575 -0.002
ENSG00000153827 E034 42.0171651 0.0003555992 6.756500e-01 8.748822e-01 2 229792973 229793130 158 - 1.624 1.643 0.063
ENSG00000153827 E035 13.4696945 0.0444864951 1.629133e-01 4.671788e-01 2 229793131 229793145 15 - 1.079 1.231 0.540
ENSG00000153827 E036 0.4905571 0.0159713155 8.631867e-01   2 229793146 229793368 223 - 0.161 0.186 0.248
ENSG00000153827 E037 1.7521670 0.0080132328 1.671692e-01 4.735508e-01 2 229794861 229795178 318 - 0.327 0.532 1.096
ENSG00000153827 E038 37.0265814 0.0201790811 5.144503e-01 7.894067e-01 2 229795179 229795330 152 - 1.608 1.549 -0.200
ENSG00000153827 E039 43.1687846 0.0003703442 1.220440e-01 4.042888e-01 2 229796591 229796782 192 - 1.679 1.607 -0.243
ENSG00000153827 E040 38.5578867 0.0003636653 2.265229e-03 3.326765e-02 2 229797690 229797831 142 - 1.664 1.515 -0.508
ENSG00000153827 E041 42.4613065 0.0003479560 2.967575e-02 1.830360e-01 2 229798875 229799049 175 - 1.685 1.584 -0.344
ENSG00000153827 E042 20.1630905 0.0006943067 4.569656e-01 7.527376e-01 2 229799283 229799383 101 - 1.349 1.300 -0.172
ENSG00000153827 E043 0.0000000       2 229802251 229802251 1 -      
ENSG00000153827 E044 38.1525513 0.0003709525 7.319757e-02 3.071509e-01 2 229802252 229802459 208 - 1.634 1.546 -0.299
ENSG00000153827 E045 26.9746138 0.0140419865 1.960600e-01 5.128546e-01 2 229803571 229803689 119 - 1.493 1.393 -0.342
ENSG00000153827 E046 43.8797996 0.0003171619 1.413108e-03 2.338412e-02 2 229803999 229804227 229 - 1.718 1.572 -0.497
ENSG00000153827 E047 20.5047438 0.0011837659 3.477733e-01 6.685990e-01 2 229805730 229805802 73 - 1.362 1.300 -0.217
ENSG00000153827 E048 16.4485880 0.0078246784 2.117563e-01 5.331860e-01 2 229805803 229805883 81 - 1.288 1.188 -0.355
ENSG00000153827 E049 2.8836529 0.0052554252 6.306982e-02 2.830916e-01 2 229805884 229806149 266 - 0.447 0.699 1.155
ENSG00000153827 E050 2.7682135 0.0101935754 3.802845e-02 2.122126e-01 2 229807319 229807704 386 - 0.410 0.699 1.348
ENSG00000153827 E051 1.3056564 0.0264969196 2.253116e-01 5.495246e-01 2 229807705 229807707 3 - 0.447 0.255 -1.167
ENSG00000153827 E052 25.0189202 0.0108013544 4.961059e-01 7.778124e-01 2 229807708 229807864 157 - 1.439 1.389 -0.175
ENSG00000153827 E053 17.9260147 0.0009856963 9.815151e-01 9.981554e-01 2 229808252 229808369 118 - 1.278 1.276 -0.008
ENSG00000153827 E054 13.7922797 0.0248049599 5.745917e-02 2.682978e-01 2 229810880 229810956 77 - 1.257 1.057 -0.714
ENSG00000153827 E055 16.1355451 0.0055148492 4.935961e-02 2.455863e-01 2 229810957 229811045 89 - 1.303 1.148 -0.547
ENSG00000153827 E056 14.8403406 0.0011909894 2.715898e-03 3.792698e-02 2 229811136 229811204 69 - 1.298 1.067 -0.822
ENSG00000153827 E057 27.7601837 0.0008219542 1.295703e-03 2.191960e-02 2 229813870 229814031 162 - 1.540 1.354 -0.641
ENSG00000153827 E058 0.0000000       2 229814032 229814046 15 -      
ENSG00000153827 E059 17.6889992 0.0027385757 2.849884e-01 6.127290e-01 2 229814233 229814325 93 - 1.308 1.231 -0.271
ENSG00000153827 E060 0.0000000       2 229814326 229814493 168 -      
ENSG00000153827 E061 19.2413222 0.0006982711 1.070926e-02 9.706531e-02 2 229815099 229815194 96 - 1.383 1.210 -0.605
ENSG00000153827 E062 13.3910596 0.0010104726 9.892983e-02 3.626675e-01 2 229815273 229815308 36 - 1.218 1.087 -0.468
ENSG00000153827 E063 23.6149179 0.0005686201 1.499626e-01 4.480818e-01 2 229818364 229818512 149 - 1.432 1.344 -0.306
ENSG00000153827 E064 13.9458603 0.0027528785 2.917910e-02 1.809159e-01 2 229829193 229829288 96 - 1.252 1.077 -0.623
ENSG00000153827 E065 11.6229235 0.0065648422 1.777552e-02 1.345930e-01 2 229830756 229830821 66 - 1.193 0.979 -0.774
ENSG00000153827 E066 7.0645694 0.0162935091 5.940549e-02 2.738332e-01 2 229830822 229830839 18 - 0.999 0.783 -0.826
ENSG00000153827 E067 1.1130009 0.0116438494 5.573709e-01 8.150005e-01 2 229831032 229831146 115 - 0.278 0.368 0.570
ENSG00000153827 E068 1.6565044 0.0476868058 3.311954e-02 1.953365e-01 2 229836172 229836847 676 - 0.224 0.564 1.985
ENSG00000153827 E069 13.4123627 0.0050283421 1.664758e-01 4.725727e-01 2 229836848 229836984 137 - 1.212 1.096 -0.413
ENSG00000153827 E070 9.9470119 0.0102714978 4.922596e-01 7.755419e-01 2 229840822 229840927 106 - 1.071 1.003 -0.249
ENSG00000153827 E071 8.6941779 0.0021383203 3.610686e-03 4.638840e-02 2 229858772 229858831 60 - 1.103 0.820 -1.060
ENSG00000153827 E072 11.4469011 0.0011979875 3.250871e-06 1.584717e-04 2 229858832 229858918 87 - 1.252 0.837 -1.521
ENSG00000153827 E073 37.7888758 0.0047306026 1.683762e-05 6.655561e-04 2 229858919 229859210 292 - 1.693 1.446 -0.842
ENSG00000153827 E074 9.8191029 0.0029450091 2.221026e-02 1.539838e-01 2 229859211 229859225 15 - 1.126 0.914 -0.778
ENSG00000153827 E075 21.4763582 0.0006284215 1.791093e-03 2.799823e-02 2 229859226 229859375 150 - 1.439 1.237 -0.704
ENSG00000153827 E076 21.7099602 0.0007481349 3.436624e-02 1.997111e-01 2 229859376 229859574 199 - 1.418 1.282 -0.472
ENSG00000153827 E077 7.3078982 0.0504977121 8.781439e-01 9.613298e-01 2 229860406 229860531 126 - 0.925 0.914 -0.042
ENSG00000153827 E078 10.3401926 0.0013049164 6.106343e-04 1.229747e-02 2 229879982 229880128 147 - 1.180 0.869 -1.144
ENSG00000153827 E079 0.1316618 0.0122859562 4.520469e-01   2 229900737 229900858 122 - 0.000 0.103 10.249
ENSG00000153827 E080 0.1141751 0.0111963219 6.385520e-01   2 229908385 229908441 57 - 0.088 0.000 -10.827
ENSG00000153827 E081 0.5070473 0.0295079710 2.467831e-01   2 229908965 229909082 118 - 0.088 0.255 1.833
ENSG00000153827 E082 0.0000000       2 229909083 229909086 4 -      
ENSG00000153827 E083 0.0000000       2 229921271 229921563 293 -      
ENSG00000153827 E084 0.7197029 0.0135097017 5.426541e-01 8.067880e-01 2 229921564 229921742 179 - 0.278 0.186 -0.752
ENSG00000153827 E085 2.8326504 0.0051077317 5.378459e-01 8.036051e-01 2 229921880 229922009 130 - 0.540 0.623 0.374
ENSG00000153827 E086 0.1139502 0.0111945023 6.385372e-01   2 229923148 229923239 92 - 0.088 0.000 -10.827

Help

Please Click HERE to learn more details about the results from DEXseq.