ENSG00000153944

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000284073 ENSG00000153944 No_inf pgwt_inf MSI2 protein_coding protein_coding 12.17449 13.92842 10.32031 1.07678 1.171526 -0.4321845 1.6866175 0.0000000 2.8087529 0.0000000 0.4624539 8.1389132 0.17140833 0.000000 0.301225 0.301225 0.001172418 0.001172418 FALSE TRUE
ENST00000416426 ENSG00000153944 No_inf pgwt_inf MSI2 protein_coding protein_coding 12.17449 13.92842 10.32031 1.07678 1.171526 -0.4321845 2.0812410 3.7822858 0.7897006 0.9600009 0.5834037 -2.2455358 0.15850833 0.273650 0.071200 -0.202450 0.693427855 0.001172418 FALSE TRUE
ENST00000579505 ENSG00000153944 No_inf pgwt_inf MSI2 protein_coding protein_coding_CDS_not_defined 12.17449 13.92842 10.32031 1.07678 1.171526 -0.4321845 0.4310748 0.0000000 1.2932245 0.0000000 1.2932245 7.0259418 0.03470000 0.000000 0.104100 0.104100 0.992847247 0.001172418 FALSE FALSE
ENST00000579590 ENSG00000153944 No_inf pgwt_inf MSI2 protein_coding protein_coding 12.17449 13.92842 10.32031 1.07678 1.171526 -0.4321845 0.4737665 1.4212995 0.0000000 1.4212995 0.0000000 -7.1611818 0.02893333 0.086800 0.000000 -0.086800 0.993236612 0.001172418 FALSE FALSE
ENST00000581523 ENSG00000153944 No_inf pgwt_inf MSI2 protein_coding protein_coding_CDS_not_defined 12.17449 13.92842 10.32031 1.07678 1.171526 -0.4321845 1.9901424 2.0607195 1.0531538 1.2976003 0.3624173 -0.9617819 0.16406667 0.141100 0.112600 -0.028500 1.000000000 0.001172418 FALSE FALSE
ENST00000582453 ENSG00000153944 No_inf pgwt_inf MSI2 protein_coding protein_coding_CDS_not_defined 12.17449 13.92842 10.32031 1.07678 1.171526 -0.4321845 0.9460123 0.0000000 1.2469332 0.0000000 0.7504087 6.9737641 0.07075833 0.000000 0.114725 0.114725 0.931139636 0.001172418 FALSE FALSE
ENST00000674522 ENSG00000153944 No_inf pgwt_inf MSI2 protein_coding protein_coding 12.17449 13.92842 10.32031 1.07678 1.171526 -0.4321845 0.7474376 1.1403634 0.5660674 1.1403634 0.3543276 -0.9977801 0.06795833 0.097025 0.048225 -0.048800 0.992847247 0.001172418   FALSE
ENST00000675379 ENSG00000153944 No_inf pgwt_inf MSI2 protein_coding protein_coding 12.17449 13.92842 10.32031 1.07678 1.171526 -0.4321845 0.4889911 1.4669733 0.0000000 0.8657838 0.0000000 -7.2064999 0.03374167 0.101225 0.000000 -0.101225 0.983547122 0.001172418   FALSE
MSTRG.12981.2 ENSG00000153944 No_inf pgwt_inf MSI2 protein_coding   12.17449 13.92842 10.32031 1.07678 1.171526 -0.4321845 0.1209983 0.0000000 0.3629950 0.0000000 0.3629950 5.2210845 0.01732500 0.000000 0.051975 0.051975 0.992847247 0.001172418 FALSE TRUE
MSTRG.12981.7 ENSG00000153944 No_inf pgwt_inf MSI2 protein_coding   12.17449 13.92842 10.32031 1.07678 1.171526 -0.4321845 1.0713297 0.5942977 1.0377911 0.3802376 0.3554817 0.7940198 0.08575833 0.039975 0.090875 0.050900 0.992847247 0.001172418 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000153944 E001 0.1138060 0.0111526788 3.793203e-01   17 57255851 57255981 131 + 0.111 0.000 -11.188
ENSG00000153944 E002 0.1145948 0.0113426085 3.791395e-01   17 57256113 57256152 40 + 0.111 0.000 -13.338
ENSG00000153944 E003 0.0000000       17 57256523 57256542 20 +      
ENSG00000153944 E004 0.1141751 0.0111905872 3.792884e-01   17 57256543 57256739 197 + 0.111 0.000 -13.338
ENSG00000153944 E005 0.1141751 0.0111905872 3.792884e-01   17 57256740 57256742 3 + 0.111 0.000 -13.338
ENSG00000153944 E006 0.2453240 0.0162566817 7.917163e-01   17 57256743 57256747 5 + 0.111 0.081 -0.506
ENSG00000153944 E007 0.9992869 0.0127563249 8.166561e-01 9.373327e-01 17 57256748 57256758 11 + 0.273 0.307 0.231
ENSG00000153944 E008 1.3587860 0.0207742997 7.998412e-01 9.311828e-01 17 57256759 57256773 15 + 0.391 0.349 -0.243
ENSG00000153944 E009 1.4725919 0.0128076363 5.631412e-01 8.176434e-01 17 57256774 57256781 8 + 0.439 0.349 -0.506
ENSG00000153944 E010 2.0776068 0.0098287322 3.533114e-01 6.734753e-01 17 57256782 57256804 23 + 0.559 0.422 -0.676
ENSG00000153944 E011 0.0000000       17 57257013 57257017 5 +      
ENSG00000153944 E012 0.1145948 0.0113426085 3.791395e-01   17 57257018 57257041 24 + 0.111 0.000 -13.338
ENSG00000153944 E013 0.3774055 0.0169470477 8.171589e-01   17 57257042 57257097 56 + 0.111 0.149 0.494
ENSG00000153944 E014 3.6305060 0.0045987617 4.456707e-02 2.320211e-01 17 57257098 57257123 26 + 0.796 0.540 -1.091
ENSG00000153944 E015 2.8589727 0.0055673440 4.157198e-03 5.110909e-02 17 57257124 57257138 15 + 0.775 0.387 -1.786
ENSG00000153944 E016 2.3848788 0.0122651521 1.232479e-02 1.063514e-01 17 57257466 57257469 4 + 0.706 0.349 -1.728
ENSG00000153944 E017 4.3003406 0.0377618107 4.844327e-01 7.709274e-01 17 57257470 57257547 78 + 0.775 0.672 -0.423
ENSG00000153944 E018 7.0549356 0.0163223076 7.482812e-01 9.097055e-01 17 57258270 57258354 85 + 0.919 0.879 -0.150
ENSG00000153944 E019 0.0000000       17 57259977 57260054 78 +      
ENSG00000153944 E020 0.0000000       17 57262115 57262150 36 +      
ENSG00000153944 E021 6.4107323 0.0049970295 6.939056e-03 7.295835e-02 17 57262151 57262192 42 + 1.014 0.725 -1.114
ENSG00000153944 E022 0.1315150 0.0122422673 7.580382e-01   17 57262193 57262433 241 + 0.000 0.081 11.441
ENSG00000153944 E023 0.1138060 0.0111526788 3.793203e-01   17 57263488 57263569 82 + 0.111 0.000 -13.338
ENSG00000153944 E024 0.7702879 0.0135671830 1.977846e-01 5.151862e-01 17 57263570 57268550 4981 + 0.111 0.307 1.816
ENSG00000153944 E025 1.1298407 0.0867796277 6.559305e-01 8.657761e-01 17 57274268 57274489 222 + 0.273 0.349 0.494
ENSG00000153944 E026 0.0000000       17 57285844 57286012 169 +      
ENSG00000153944 E027 0.0000000       17 57294685 57294789 105 +      
ENSG00000153944 E028 0.2453209 0.0161990723 7.912070e-01   17 57310131 57310326 196 + 0.111 0.081 -0.506
ENSG00000153944 E029 0.0000000       17 57364922 57365021 100 +      
ENSG00000153944 E030 0.0000000       17 57370949 57370991 43 +      
ENSG00000153944 E031 6.0166718 0.0245825629 4.771698e-03 5.633380e-02 17 57401379 57401471 93 + 1.014 0.672 -1.336
ENSG00000153944 E032 0.1138060 0.0111526788 3.793203e-01   17 57406812 57407039 228 + 0.111 0.000 -13.338
ENSG00000153944 E033 0.0000000       17 57432586 57432614 29 +      
ENSG00000153944 E034 0.0000000       17 57440690 57440739 50 +      
ENSG00000153944 E035 0.0000000       17 57444487 57444752 266 +      
ENSG00000153944 E036 0.0000000       17 57487061 57487289 229 +      
ENSG00000153944 E037 0.0000000       17 57524309 57524378 70 +      
ENSG00000153944 E038 3.0418034 0.0048599888 1.508287e-01 4.493810e-01 17 57529676 57529724 49 + 0.706 0.513 -0.854
ENSG00000153944 E039 0.1308632 0.0122706719 7.579181e-01   17 57556990 57557131 142 + 0.000 0.081 11.441
ENSG00000153944 E040 0.0000000       17 57565923 57565995 73 +      
ENSG00000153944 E041 2.7948511 0.0054758946 1.544588e-01 4.549520e-01 17 57596868 57596902 35 + 0.681 0.485 -0.884
ENSG00000153944 E042 4.3977220 0.0041727656 1.807767e-01 4.935234e-01 17 57596903 57596950 48 + 0.816 0.653 -0.666
ENSG00000153944 E043 8.2581632 0.0017356784 8.799787e-03 8.535456e-02 17 57615970 57616084 115 + 1.093 0.842 -0.933
ENSG00000153944 E044 0.1308632 0.0122706719 7.579181e-01   17 57616085 57616631 547 + 0.000 0.081 11.441
ENSG00000153944 E045 0.9648759 0.1688556428 3.181806e-01 6.436474e-01 17 57625572 57626914 1343 + 0.391 0.209 -1.244
ENSG00000153944 E046 0.2620121 0.0161545845 3.824737e-01   17 57626915 57627228 314 + 0.000 0.149 12.356
ENSG00000153944 E047 4.8415949 0.0034109882 2.002860e-02 1.442657e-01 17 57627229 57627303 75 + 0.903 0.632 -1.091
ENSG00000153944 E048 4.4518686 0.0038595650 7.305917e-01 9.017246e-01 17 57627304 57631790 4487 + 0.753 0.708 -0.184
ENSG00000153944 E049 9.8523783 0.0017450854 2.838355e-01 6.115134e-01 17 57631791 57633183 1393 + 1.082 0.984 -0.362
ENSG00000153944 E050 0.0000000       17 57650650 57650673 24 +      
ENSG00000153944 E051 4.3836960 0.0033647045 9.370429e-02 3.519945e-01 17 57652099 57652161 63 + 0.835 0.632 -0.828
ENSG00000153944 E052 0.0000000       17 57655695 57655744 50 +      
ENSG00000153944 E053 0.0000000       17 57671474 57671574 101 +      
ENSG00000153944 E054 1.8478993 0.0078914230 6.946284e-01 8.840083e-01 17 57674918 57674971 54 + 0.483 0.422 -0.313
ENSG00000153944 E055 7.7062107 0.0134166638 1.090649e-01 3.811530e-01 17 57674972 57675126 155 + 1.026 0.855 -0.643
ENSG00000153944 E056 5.0406562 0.0027719082 3.541495e-01 6.741386e-01 17 57676987 57677059 73 + 0.835 0.725 -0.436
ENSG00000153944 E057 5.0143026 0.0031023773 3.585453e-04 8.127657e-03 17 57679549 57679606 58 + 0.976 0.565 -1.663
ENSG00000153944 E058 170.2433132 0.0001730189 9.597522e-22 3.691986e-19 17 57679607 57684689 5083 + 2.125 2.270 0.485

Help

Please Click HERE to learn more details about the results from DEXseq.