ENSG00000154122

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000284268 ENSG00000154122 No_inf pgwt_inf ANKH protein_coding protein_coding 63.47279 33.34618 75.26237 1.841447 2.901825 1.174166 13.073407 9.049654 14.50326 0.2750666 0.3462211 0.6798441 0.2206333 0.273150 0.19415 -0.079000 0.992847247 0.000740367 FALSE TRUE
ENST00000502585 ENSG00000154122 No_inf pgwt_inf ANKH protein_coding retained_intron 63.47279 33.34618 75.26237 1.841447 2.901825 1.174166 16.735938 8.800675 20.06151 1.5375560 1.8913761 1.1878251 0.2629667 0.260600 0.26490 0.004300 1.000000000 0.000740367 FALSE TRUE
ENST00000503939 ENSG00000154122 No_inf pgwt_inf ANKH protein_coding protein_coding_CDS_not_defined 63.47279 33.34618 75.26237 1.841447 2.901825 1.174166 27.865621 14.975667 33.80108 1.2284477 1.5571824 1.1739127 0.4400167 0.448875 0.44950 0.000625 1.000000000 0.000740367 FALSE TRUE
ENST00000513115 ENSG00000154122 No_inf pgwt_inf ANKH protein_coding retained_intron 63.47279 33.34618 75.26237 1.841447 2.901825 1.174166 4.849416 0.000000 6.06759 0.0000000 0.8186397 9.2473555 0.0610500 0.000000 0.08040 0.080400 0.000740367 0.000740367 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000154122 E001 317.6199024 0.0005858483 2.319154e-06 0.0001183794 5 14704800 14711087 6288 - 2.464 2.536 0.240
ENSG00000154122 E002 71.7747007 0.0002176497 5.387497e-01 0.8041839125 5 14711088 14711310 223 - 1.861 1.841 -0.065
ENSG00000154122 E003 32.2512837 0.0004442044 8.674838e-01 0.9579839518 5 14712874 14712973 100 - 1.516 1.509 -0.022
ENSG00000154122 E004 36.6728034 0.0005357263 6.772946e-01 0.8758046525 5 14713544 14713667 124 - 1.558 1.581 0.079
ENSG00000154122 E005 33.2650662 0.0025949503 5.087006e-01 0.7857628121 5 14716706 14716835 130 - 1.540 1.505 -0.119
ENSG00000154122 E006 0.1141751 0.0111853654 1.000000e+00   5 14716836 14717088 253 - 0.074 0.000 -10.749
ENSG00000154122 E007 0.3589051 0.0166073879 1.000000e+00   5 14741292 14741378 87 - 0.137 0.121 -0.204
ENSG00000154122 E008 0.4908428 0.1218154361 6.141079e-01   5 14741457 14741826 370 - 0.137 0.216 0.795
ENSG00000154122 E009 34.6012799 0.0004411910 5.656119e-01 0.8188126228 5 14741827 14741922 96 - 1.553 1.526 -0.093
ENSG00000154122 E010 34.3539553 0.0070503605 6.009087e-01 0.8380800140 5 14745870 14745962 93 - 1.551 1.522 -0.100
ENSG00000154122 E011 36.9708587 0.0009585325 9.421400e-01 0.9853692523 5 14749172 14749306 135 - 1.571 1.570 -0.004
ENSG00000154122 E012 45.8209660 0.0003397818 2.269125e-01 0.5515275019 5 14751069 14751239 171 - 1.681 1.630 -0.176
ENSG00000154122 E013 29.4006020 0.0004884872 4.318990e-01 0.7346185778 5 14755861 14755944 84 - 1.490 1.449 -0.143
ENSG00000154122 E014 28.8115836 0.0078802676 3.085782e-02 0.1875350053 5 14758480 14758598 119 - 1.518 1.373 -0.501
ENSG00000154122 E015 0.2283502 0.2506179583 5.593282e-01   5 14768162 14768541 380 - 0.137 0.000 -9.947
ENSG00000154122 E016 0.7998908 0.0131759376 2.769760e-02 0.1759218232 5 14768616 14768974 359 - 0.362 0.000 -13.479
ENSG00000154122 E017 15.7171975 0.0008569131 5.603179e-02 0.2646120081 5 14768975 14769006 32 - 1.266 1.122 -0.511
ENSG00000154122 E018 27.6172537 0.0012033629 4.441084e-04 0.0096196898 5 14769007 14769191 185 - 1.520 1.309 -0.732
ENSG00000154122 E019 0.2623781 0.0161333735 1.049086e-01   5 14788116 14788217 102 - 0.000 0.216 12.166
ENSG00000154122 E020 0.5071915 0.0344009476 1.279030e-01   5 14868415 14868708 294 - 0.074 0.294 2.381
ENSG00000154122 E021 0.3936739 0.0159511214 3.373232e-02   5 14868709 14869030 322 - 0.000 0.294 12.743
ENSG00000154122 E022 0.8670295 0.0166806588 2.788256e-01 0.6069519854 5 14869031 14870182 1152 - 0.192 0.360 1.211
ENSG00000154122 E023 0.3594960 0.0165813713 1.000000e+00   5 14870183 14871351 1169 - 0.137 0.121 -0.204
ENSG00000154122 E024 39.6710496 0.0045201502 2.935550e-01 0.6219283655 5 14871352 14871778 427 - 1.622 1.566 -0.191

Help

Please Click HERE to learn more details about the results from DEXseq.