ENSG00000154380

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000358675 ENSG00000154380 No_inf pgwt_inf ENAH protein_coding retained_intron 37.53869 77.64519 16.69141 3.465294 1.002605 -2.217113 7.646963 18.7908087 2.08620473 1.7191095 0.44833702 -3.164943 0.15891667 0.242975 0.124375 -0.118600 0.959494988 0.009933971 FALSE TRUE
ENST00000366843 ENSG00000154380 No_inf pgwt_inf ENAH protein_coding protein_coding 37.53869 77.64519 16.69141 3.465294 1.002605 -2.217113 3.270915 8.8253777 0.04707806 1.0078174 0.04707806 -7.274212 0.05687500 0.114175 0.003200 -0.110975 0.009933971 0.009933971 FALSE TRUE
ENST00000483952 ENSG00000154380 No_inf pgwt_inf ENAH protein_coding protein_coding_CDS_not_defined 37.53869 77.64519 16.69141 3.465294 1.002605 -2.217113 6.014295 13.5827365 3.36167557 1.7538926 1.31132097 -2.011298 0.13918333 0.173400 0.192450 0.019050 1.000000000 0.009933971   FALSE
ENST00000497899 ENSG00000154380 No_inf pgwt_inf ENAH protein_coding protein_coding 37.53869 77.64519 16.69141 3.465294 1.002605 -2.217113 2.626926 6.5759836 1.15869186 1.4396660 0.71061990 -2.494504 0.05436667 0.082950 0.071875 -0.011075 0.992847247 0.009933971 FALSE TRUE
ENST00000635051 ENSG00000154380 No_inf pgwt_inf ENAH protein_coding protein_coding 37.53869 77.64519 16.69141 3.465294 1.002605 -2.217113 1.652925 2.8248568 1.00232754 0.5452552 0.29051658 -1.485600 0.05280833 0.035825 0.059300 0.023475 0.992847247 0.009933971 FALSE TRUE
MSTRG.2757.6 ENSG00000154380 No_inf pgwt_inf ENAH protein_coding   37.53869 77.64519 16.69141 3.465294 1.002605 -2.217113 1.113079 0.5721679 1.34242298 0.5721679 0.10729933 1.216039 0.05480000 0.006650 0.081100 0.074450 0.149175484 0.009933971 FALSE TRUE
MSTRG.2757.7 ENSG00000154380 No_inf pgwt_inf ENAH protein_coding   37.53869 77.64519 16.69141 3.465294 1.002605 -2.217113 14.788653 25.1984501 7.69300716 1.7840965 0.26206456 -1.710414 0.47724167 0.326575 0.467700 0.141125 0.992847247 0.009933971 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000154380 E001 0.1308632 1.223211e-02 7.571598e-01   1 225486743 225486764 22 - 0.000 0.044 7.942
ENSG00000154380 E002 0.1308632 1.223211e-02 7.571598e-01   1 225486765 225486828 64 - 0.000 0.044 9.792
ENSG00000154380 E003 0.1311489 1.225783e-02 7.572638e-01   1 225486829 225486834 6 - 0.000 0.044 9.791
ENSG00000154380 E004 9.7204165 2.036111e-02 2.953950e-06 1.464177e-04 1 225486835 225487239 405 - 0.000 0.951 15.415
ENSG00000154380 E005 260.7825144 9.426685e-05 4.128420e-18 1.178286e-15 1 225487240 225495479 8240 - 2.048 2.291 0.814
ENSG00000154380 E006 344.2883465 6.852917e-05 9.111310e-01 9.737054e-01 1 225495480 225496884 1405 - 2.379 2.385 0.021
ENSG00000154380 E007 172.8402404 1.083100e-04 7.459405e-01 9.089393e-01 1 225496885 225497422 538 - 2.091 2.086 -0.019
ENSG00000154380 E008 71.9382491 1.894383e-04 3.674537e-02 2.082042e-01 1 225497423 225497633 211 - 1.788 1.696 -0.310
ENSG00000154380 E009 50.0557435 2.833379e-04 8.774107e-02 3.399374e-01 1 225497634 225497812 179 - 1.633 1.543 -0.307
ENSG00000154380 E010 24.8401604 9.048624e-04 2.518756e-01 5.787839e-01 1 225498347 225498404 58 - 1.336 1.251 -0.296
ENSG00000154380 E011 35.2841462 1.374820e-03 5.128392e-01 7.884467e-01 1 225500992 225501070 79 - 1.444 1.404 -0.140
ENSG00000154380 E012 0.2631768 1.609969e-02 1.000000e+00   1 225501071 225501256 186 - 0.000 0.084 10.739
ENSG00000154380 E013 0.5257018 1.583221e-02 8.583361e-01   1 225504991 225505053 63 - 0.000 0.155 11.711
ENSG00000154380 E014 29.8422829 1.102266e-03 8.500065e-01 9.508187e-01 1 225507951 225508017 67 - 1.325 1.343 0.063
ENSG00000154380 E015 0.3932413 2.605458e-02 1.000000e+00   1 225508389 225508583 195 - 0.000 0.121 11.235
ENSG00000154380 E016 25.8248414 5.312660e-04 8.643134e-01 9.566868e-01 1 225511811 225511859 49 - 1.289 1.279 -0.034
ENSG00000154380 E017 30.4594148 2.092849e-03 1.784052e-01 4.904422e-01 1 225512657 225512714 58 - 1.427 1.334 -0.320
ENSG00000154380 E018 34.0790998 4.166680e-04 2.063149e-02 1.468782e-01 1 225512871 225513016 146 - 1.517 1.371 -0.500
ENSG00000154380 E019 40.5159825 3.657542e-04 4.561259e-02 2.347673e-01 1 225514596 225514900 305 - 1.565 1.449 -0.399
ENSG00000154380 E020 5.3142331 2.600859e-03 2.492956e-01 5.762227e-01 1 225514901 225515397 497 - 0.510 0.696 0.828
ENSG00000154380 E021 20.0676336 6.876404e-04 1.450287e-01 4.406514e-01 1 225517196 225517306 111 - 1.276 1.159 -0.416
ENSG00000154380 E022 12.3262389 9.914974e-03 8.613289e-01 9.554017e-01 1 225517307 225517990 684 - 0.997 0.981 -0.060
ENSG00000154380 E023 3.2743800 5.977442e-02 9.974771e-02 3.642572e-01 1 225519044 225519197 154 - 0.738 0.467 -1.211
ENSG00000154380 E024 62.1156177 3.600282e-04 9.667178e-02 3.581024e-01 1 225519198 225519417 220 - 1.715 1.636 -0.267
ENSG00000154380 E025 34.4771893 4.653075e-04 2.593881e-02 1.696843e-01 1 225519418 225519565 148 - 1.517 1.377 -0.480
ENSG00000154380 E026 0.1311489 1.225783e-02 7.572638e-01   1 225524599 225524689 91 - 0.000 0.044 9.791
ENSG00000154380 E027 18.5734717 7.638100e-04 3.949512e-01 7.078397e-01 1 225530554 225530638 85 - 1.207 1.135 -0.254
ENSG00000154380 E028 0.0000000       1 225531046 225531057 12 -      
ENSG00000154380 E029 0.2450383 1.623808e-02 1.933566e-01   1 225535507 225535563 57 - 0.193 0.044 -2.382
ENSG00000154380 E030 29.0174461 4.922549e-04 7.320497e-01 9.023152e-01 1 225554906 225555083 178 - 1.347 1.326 -0.075
ENSG00000154380 E031 23.7827401 9.955024e-04 1.586591e-01 4.610805e-01 1 225567249 225567414 166 - 1.336 1.230 -0.372
ENSG00000154380 E032 0.1316618 1.230239e-02 7.572016e-01   1 225580167 225580257 91 - 0.000 0.044 9.791
ENSG00000154380 E033 27.2202860 2.418553e-03 1.119911e-01 3.869759e-01 1 225652686 225653235 550 - 1.398 1.284 -0.398

Help

Please Click HERE to learn more details about the results from DEXseq.