ENSG00000156265

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000399947 ENSG00000156265 No_inf pgwt_inf MAP3K7CL protein_coding protein_coding 45.12678 108.339 6.617094 1.547242 0.5196872 -4.031166 0.3063986 0.0000 0.5115396 0.00000 0.1810320 5.704705 0.03416667 0.0000 0.08200 0.08200 0.007926782 0.007926782 FALSE TRUE
ENST00000470800 ENSG00000156265 No_inf pgwt_inf MAP3K7CL protein_coding protein_coding_CDS_not_defined 45.12678 108.339 6.617094 1.547242 0.5196872 -4.031166 43.2861337 106.6403 4.2094626 1.34278 0.9207621 -4.659685 0.85477500 0.9844 0.64865 -0.33575 0.038661724 0.007926782   FALSE
ENST00000545939 ENSG00000156265 No_inf pgwt_inf MAP3K7CL protein_coding protein_coding 45.12678 108.339 6.617094 1.547242 0.5196872 -4.031166 0.3623162 0.0000 1.0869487 0.00000 1.0869487 6.777352 0.05396667 0.0000 0.16190 0.16190 0.929715806 0.007926782 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000156265 E001 0.0000000       21 29077471 29077474 4 +      
ENSG00000156265 E002 0.0000000       21 29077475 29077495 21 +      
ENSG00000156265 E003 0.1311489 1.241969e-02 2.440441e-01   21 29077496 29077632 137 + 0.000 0.025 6.316
ENSG00000156265 E004 0.2461098 1.636906e-02 3.347837e-02   21 29077633 29077713 81 + 0.301 0.025 -4.056
ENSG00000156265 E005 0.2277562 1.579432e-02 7.386581e-04   21 29080552 29080708 157 + 0.477 0.000 -15.633
ENSG00000156265 E006 0.3423510 1.677755e-02 5.156607e-05   21 29085072 29085143 72 + 0.602 0.000 -16.179
ENSG00000156265 E007 0.4918535 1.042831e-01 1.224623e-02   21 29085813 29085860 48 + 0.477 0.049 -4.056
ENSG00000156265 E008 0.7026389 1.454557e-02 1.615891e-06 8.656021e-05 21 29085861 29085876 16 + 0.778 0.025 -6.378
ENSG00000156265 E009 0.9806337 1.390674e-02 5.205859e-04 1.084609e-02 21 29085877 29085917 41 + 0.698 0.093 -4.056
ENSG00000156265 E010 0.6048254 1.577437e-02 1.004439e-03   21 29091501 29091576 76 + 0.602 0.049 -4.641
ENSG00000156265 E011 1.0323861 1.335422e-02 4.397764e-01 7.405067e-01 21 29091668 29091761 94 + 0.301 0.152 -1.248
ENSG00000156265 E012 0.0000000       21 29092254 29092438 185 +      
ENSG00000156265 E013 0.8840965 5.004256e-02 5.583553e-02 2.639905e-01 21 29092439 29092581 143 + 0.477 0.114 -2.734
ENSG00000156265 E014 0.0000000       21 29102508 29102640 133 +      
ENSG00000156265 E015 0.3769858 1.677821e-02 8.093820e-02   21 29109040 29109131 92 + 0.301 0.049 -3.056
ENSG00000156265 E016 0.2453240 1.620329e-02 3.354365e-02   21 29109132 29109183 52 + 0.301 0.025 -4.056
ENSG00000156265 E017 0.6401626 1.531727e-02 2.133032e-01 5.352567e-01 21 29109184 29109791 608 + 0.301 0.093 -2.056
ENSG00000156265 E018 0.0000000       21 29122055 29122213 159 +      
ENSG00000156265 E019 0.0000000       21 29130638 29130643 6 +      
ENSG00000156265 E020 0.0000000       21 29130644 29130667 24 +      
ENSG00000156265 E021 0.0000000       21 29130668 29130794 127 +      
ENSG00000156265 E022 0.0000000       21 29130795 29130923 129 +      
ENSG00000156265 E023 0.3946917 3.409659e-02 1.000000e+00   21 29130961 29131050 90 + 0.000 0.072 9.241
ENSG00000156265 E024 0.1139502 1.128323e-02 8.764404e-03   21 29131257 29131491 235 + 0.301 0.000 -14.713
ENSG00000156265 E025 0.5246759 1.592658e-02 1.000000e+00   21 29133306 29133414 109 + 0.000 0.093 9.696
ENSG00000156265 E026 15.3281589 9.925072e-04 2.280734e-02 1.567315e-01 21 29145559 29145662 104 + 0.477 0.898 1.790
ENSG00000156265 E027 22.6278798 5.897495e-04 5.827332e-02 2.708815e-01 21 29145663 29145707 45 + 0.778 1.045 1.015
ENSG00000156265 E028 25.5679950 8.268200e-04 6.121060e-01 8.435135e-01 21 29149189 29149250 62 + 1.041 1.085 0.161
ENSG00000156265 E029 43.2416233 4.398216e-04 9.341977e-01 9.818267e-01 21 29159941 29160056 116 + 1.322 1.295 -0.092
ENSG00000156265 E030 88.1258769 1.802998e-04 4.698554e-01 7.610295e-01 21 29174712 29174908 197 + 1.568 1.596 0.096
ENSG00000156265 E031 116.8735574 1.546321e-04 8.605765e-01 9.551341e-01 21 29174909 29175158 250 + 1.724 1.714 -0.033
ENSG00000156265 E032 226.0070221 8.339865e-05 3.757848e-01 6.933447e-01 21 29175159 29175889 731 + 1.986 1.997 0.037

Help

Please Click HERE to learn more details about the results from DEXseq.