ENSG00000156471

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000517309 ENSG00000156471 No_inf pgwt_inf PTDSS1 protein_coding protein_coding 153.9375 48.22172 201.4236 0.2426076 5.519179 2.06225 109.07378 46.96235 141.68597 0.1472577 0.3854203 1.592915 0.7778000 0.973925 0.705075 -0.268850 9.472983e-05 2.359601e-07 FALSE TRUE
ENST00000517557 ENSG00000156471 No_inf pgwt_inf PTDSS1 protein_coding retained_intron 153.9375 48.22172 201.4236 0.2426076 5.519179 2.06225 12.80359 0.00000 12.21723 0.0000000 4.4652513 10.255882 0.0610000 0.000000 0.060025 0.060025 4.167372e-01 2.359601e-07 FALSE TRUE
ENST00000518776 ENSG00000156471 No_inf pgwt_inf PTDSS1 protein_coding protein_coding_CDS_not_defined 153.9375 48.22172 201.4236 0.2426076 5.519179 2.06225 30.72635 0.00000 45.82641 0.0000000 5.3385600 12.162278 0.1480917 0.000000 0.226625 0.226625 2.359601e-07 2.359601e-07 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000156471 E001 0.6391319 1.509225e-02 9.963573e-03   8 96261902 96261911 10 + 0.057 0.434 3.621
ENSG00000156471 E002 1.1295573 3.719790e-02 1.036850e-02 9.485658e-02 8 96261912 96261912 1 + 0.152 0.553 2.621
ENSG00000156471 E003 18.8257709 7.549226e-04 1.962246e-01 5.130407e-01 8 96261913 96261966 54 + 1.221 1.317 0.337
ENSG00000156471 E004 169.8083039 3.003986e-04 2.011447e-03 3.055213e-02 8 96261967 96262219 253 + 2.204 2.119 -0.284
ENSG00000156471 E005 121.8088428 7.878318e-04 1.764129e-01 4.875339e-01 8 96273299 96273390 92 + 2.051 2.006 -0.149
ENSG00000156471 E006 0.0000000       8 96283597 96283763 167 +      
ENSG00000156471 E007 86.5236878 1.914521e-03 1.112130e-01 3.853343e-01 8 96284109 96284153 45 + 1.909 1.843 -0.222
ENSG00000156471 E008 146.2622235 1.042277e-04 1.870866e-02 1.384613e-01 8 96287022 96287146 125 + 2.135 2.068 -0.226
ENSG00000156471 E009 0.3600600 1.660755e-02 6.885320e-01   8 96287147 96287388 242 + 0.107 0.155 0.621
ENSG00000156471 E010 122.9365488 1.350756e-04 1.647095e-03 2.621995e-02 8 96295098 96295191 94 + 2.068 1.968 -0.336
ENSG00000156471 E011 91.0268201 3.685323e-04 2.985446e-02 1.836299e-01 8 96295192 96295256 65 + 1.935 1.854 -0.272
ENSG00000156471 E012 185.0556673 8.441426e-05 2.836496e-02 1.783263e-01 8 96299694 96299845 152 + 2.234 2.179 -0.185
ENSG00000156471 E013 258.3441780 6.930852e-05 3.802830e-03 4.797458e-02 8 96304040 96304181 142 + 2.379 2.318 -0.205
ENSG00000156471 E014 251.2062069 9.384867e-05 1.273382e-01 4.134482e-01 8 96306444 96306556 113 + 2.360 2.328 -0.108
ENSG00000156471 E015 184.9882819 1.338322e-04 4.598439e-01 7.542320e-01 8 96309557 96309622 66 + 2.224 2.206 -0.060
ENSG00000156471 E016 167.0026942 1.356981e-04 7.149868e-01 8.942135e-01 8 96320246 96320345 100 + 2.178 2.169 -0.030
ENSG00000156471 E017 133.0033039 1.065583e-04 9.385100e-01 9.837450e-01 8 96330213 96330281 69 + 2.077 2.076 -0.006
ENSG00000156471 E018 11.8315064 8.553350e-03 3.310889e-08 2.592357e-06 8 96330317 96331025 709 + 0.862 1.360 1.801
ENSG00000156471 E019 132.6227572 1.426825e-04 7.636016e-02 3.144609e-01 8 96331026 96331095 70 + 2.061 2.113 0.175
ENSG00000156471 E020 116.6659103 3.364443e-04 1.565259e-01 4.579785e-01 8 96333457 96333486 30 + 2.008 2.053 0.153
ENSG00000156471 E021 256.1573421 7.080862e-05 3.605479e-01 6.800514e-01 8 96333487 96333677 191 + 2.354 2.374 0.066
ENSG00000156471 E022 1082.4809220 5.171531e-05 8.712630e-11 1.039368e-08 8 96333678 96336995 3318 + 2.968 3.026 0.193

Help

Please Click HERE to learn more details about the results from DEXseq.