ENSG00000157540

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000398960 ENSG00000157540 No_inf pgwt_inf DYRK1A protein_coding protein_coding 12.29632 11.49145 12.63717 0.5561239 0.2347057 0.1369986 1.1305110 1.668986 0.5074990 1.6689860 0.5074990 -1.6979621 0.09114167 0.138175 0.04080 -0.097375 1.0000000000 0.0002595307 FALSE TRUE
ENST00000643624 ENSG00000157540 No_inf pgwt_inf DYRK1A protein_coding protein_coding 12.29632 11.49145 12.63717 0.5561239 0.2347057 0.1369986 2.3665052 3.326143 0.5666777 1.2909425 0.5666777 -2.5323441 0.19513333 0.292475 0.04695 -0.245525 0.7378514339 0.0002595307 FALSE TRUE
ENST00000643854 ENSG00000157540 No_inf pgwt_inf DYRK1A protein_coding protein_coding 12.29632 11.49145 12.63717 0.5561239 0.2347057 0.1369986 0.4659617 0.000000 1.3978850 0.0000000 0.8124538 7.1373857 0.03580000 0.000000 0.10740 0.107400 0.9716538398 0.0002595307 FALSE TRUE
ENST00000644942 ENSG00000157540 No_inf pgwt_inf DYRK1A protein_coding protein_coding 12.29632 11.49145 12.63717 0.5561239 0.2347057 0.1369986 1.4545281 1.231763 1.0714262 0.8217844 0.6192110 -0.1994541 0.12125833 0.106200 0.08750 -0.018700 1.0000000000 0.0002595307 FALSE TRUE
ENST00000646224 ENSG00000157540 No_inf pgwt_inf DYRK1A protein_coding protein_coding_CDS_not_defined 12.29632 11.49145 12.63717 0.5561239 0.2347057 0.1369986 2.2159682 0.000000 4.3151592 0.0000000 0.9171419 8.7566094 0.17258333 0.000000 0.33850 0.338500 0.0002595307 0.0002595307 FALSE TRUE
ENST00000647188 ENSG00000157540 No_inf pgwt_inf DYRK1A protein_coding protein_coding 12.29632 11.49145 12.63717 0.5561239 0.2347057 0.1369986 2.6822750 3.206266 2.6108642 0.1952453 0.6830454 -0.2953442 0.22041667 0.283575 0.20515 -0.078425 0.9928472467 0.0002595307 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000157540 E001 0.0000000       21 37365573 37365789 217 +      
ENSG00000157540 E002 0.0000000       21 37365790 37365834 45 +      
ENSG00000157540 E003 1.0159803 0.0182359939 0.228484530 0.55369898 21 37365835 37366185 351 + 0.184 0.374 1.377
ENSG00000157540 E004 0.0000000       21 37366773 37366855 83 +      
ENSG00000157540 E005 1.5067569 0.0087926841 0.378701922 0.69586739 21 37366856 37366933 78 + 0.312 0.451 0.792
ENSG00000157540 E006 6.2653716 0.0024888256 0.666964476 0.87082946 21 37366934 37367100 167 + 0.880 0.840 -0.152
ENSG00000157540 E007 18.1609245 0.0008190629 0.325438030 0.64984355 21 37367101 37367556 456 + 1.311 1.252 -0.208
ENSG00000157540 E008 2.4229806 0.1408046866 0.307449810 0.63388537 21 37367557 37367580 24 + 0.619 0.451 -0.793
ENSG00000157540 E009 3.5010178 0.0042106169 0.085564219 0.33490099 21 37367581 37367628 48 + 0.759 0.545 -0.919
ENSG00000157540 E010 0.0000000       21 37368016 37368058 43 +      
ENSG00000157540 E011 0.0000000       21 37368059 37368132 74 +      
ENSG00000157540 E012 0.4739622 0.0240515376 0.249915040   21 37375094 37375117 24 + 0.253 0.089 -1.793
ENSG00000157540 E013 0.3766141 0.0168756360 0.687803192   21 37410570 37410670 101 + 0.101 0.163 0.792
ENSG00000157540 E014 0.0000000       21 37415490 37415565 76 +      
ENSG00000157540 E015 1.0171325 0.0129287893 0.226186363 0.55069387 21 37418905 37420298 1394 + 0.184 0.374 1.377
ENSG00000157540 E016 2.0611418 0.0073901087 0.295446225 0.62349482 21 37420299 37420311 13 + 0.560 0.414 -0.723
ENSG00000157540 E017 2.0789977 0.0077116964 0.571314622 0.82256538 21 37420312 37420327 16 + 0.527 0.451 -0.378
ENSG00000157540 E018 2.5064777 0.0058672073 0.325176747 0.64964371 21 37420328 37420374 47 + 0.454 0.598 0.685
ENSG00000157540 E019 1.0328129 0.0114560957 0.044612382 0.23203839 21 37420375 37420384 10 + 0.101 0.414 2.599
ENSG00000157540 E020 0.2453240 0.0161975914 0.900741341   21 37421774 37421812 39 + 0.101 0.089 -0.208
ENSG00000157540 E021 0.6044509 0.0160082878 0.534056113   21 37421813 37421866 54 + 0.253 0.163 -0.793
ENSG00000157540 E022 1.1467773 0.0177650721 0.145790868 0.44154804 21 37425690 37425781 92 + 0.184 0.414 1.599
ENSG00000157540 E023 0.2446691 0.0161371830 0.900430464   21 37428867 37428908 42 + 0.101 0.089 -0.208
ENSG00000157540 E024 0.9821449 0.0124138489 0.821991827 0.93944039 21 37430269 37430400 132 + 0.312 0.281 -0.208
ENSG00000157540 E025 0.1316618 0.0122514801 0.630753963   21 37456130 37456308 179 + 0.000 0.089 9.942
ENSG00000157540 E026 7.2631256 0.0020751363 0.821472319 0.93917428 21 37472684 37472779 96 + 0.923 0.906 -0.062
ENSG00000157540 E027 7.9505513 0.0293364260 0.490307332 0.77445504 21 37472780 37472880 101 + 0.894 0.985 0.339
ENSG00000157540 E028 0.4905643 0.0732392570 0.880626098   21 37478181 37478207 27 + 0.184 0.163 -0.208
ENSG00000157540 E029 5.8714300 0.0026202634 0.401555263 0.71264671 21 37478208 37478284 77 + 0.880 0.795 -0.329
ENSG00000157540 E030 3.6649211 0.0044743486 0.425647002 0.73010103 21 37478285 37478300 16 + 0.717 0.622 -0.401
ENSG00000157540 E031 14.7642785 0.0009506356 0.384491098 0.69992328 21 37480638 37480826 189 + 1.151 1.223 0.256
ENSG00000157540 E032 0.3762480 0.2108967446 0.728515216   21 37480827 37481649 823 + 0.101 0.163 0.792
ENSG00000157540 E033 0.1139502 0.0111323215 0.457605663   21 37482259 37482279 21 + 0.101 0.000 -11.003
ENSG00000157540 E034 0.1138060 0.0111090644 0.457633979   21 37486148 37486466 319 + 0.101 0.000 -11.003
ENSG00000157540 E035 15.0674454 0.0009363021 0.161485788 0.46476739 21 37486467 37486614 148 + 1.135 1.246 0.396
ENSG00000157540 E036 0.0000000       21 37486615 37486639 25 +      
ENSG00000157540 E037 0.0000000       21 37486640 37486667 28 +      
ENSG00000157540 E038 0.6852960 0.0137238143 0.005456263 0.06167946 21 37486668 37488127 1460 + 0.411 0.000 -13.354
ENSG00000157540 E039 0.0000000       21 37488785 37488863 79 +      
ENSG00000157540 E040 19.0138969 0.0008507612 0.276743709 0.60482571 21 37490175 37490461 287 + 1.333 1.268 -0.227
ENSG00000157540 E041 11.4448123 0.0041282811 0.079308904 0.32148690 21 37493017 37493163 147 + 1.167 1.024 -0.517
ENSG00000157540 E042 0.0000000       21 37496091 37496117 27 +      
ENSG00000157540 E043 8.3951945 0.0019642831 0.949823842 0.98727969 21 37496118 37496258 141 + 0.962 0.974 0.047
ENSG00000157540 E044 0.9827359 0.0124509608 0.821853088 0.93942752 21 37501326 37505282 3957 + 0.312 0.281 -0.208
ENSG00000157540 E045 22.7160074 0.0048689899 0.933309725 0.98143129 21 37505283 37505589 307 + 1.364 1.376 0.043
ENSG00000157540 E046 13.9071372 0.0015777337 0.074401432 0.30991843 21 37506099 37506223 125 + 1.238 1.109 -0.462
ENSG00000157540 E047 0.0000000       21 37506224 37506270 47 +      
ENSG00000157540 E048 0.0000000       21 37506271 37506354 84 +      
ENSG00000157540 E049 69.6175412 0.0002345971 0.577933637 0.82555165 21 37511911 37513010 1100 + 1.851 1.839 -0.040
ENSG00000157540 E050 276.5083764 0.0037391916 0.143407538 0.43806770 21 37513011 37526358 13348 + 2.420 2.453 0.110

Help

Please Click HERE to learn more details about the results from DEXseq.