ENSG00000157593

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000393810 ENSG00000157593 No_inf pgwt_inf SLC35B2 protein_coding protein_coding 32.44206 43.07334 27.33472 2.349676 0.7725055 -0.6558678 2.2915396 4.003789 0.4947248 2.820531 0.4947248 -2.9913961 0.06412500 0.084975 0.017325 -0.067650 9.696996e-01 1.878059e-06 FALSE TRUE
ENST00000393812 ENSG00000157593 No_inf pgwt_inf SLC35B2 protein_coding protein_coding 32.44206 43.07334 27.33472 2.349676 0.7725055 -0.6558678 12.5104958 15.070000 11.2648304 3.722680 1.0795435 -0.4195307 0.39697500 0.359600 0.415525 0.055925 9.932366e-01 1.878059e-06 FALSE TRUE
ENST00000495706 ENSG00000157593 No_inf pgwt_inf SLC35B2 protein_coding protein_coding_CDS_not_defined 32.44206 43.07334 27.33472 2.349676 0.7725055 -0.6558678 3.5595191 7.235356 1.7895762 5.356237 1.7895762 -2.0093994 0.09548333 0.159950 0.062600 -0.097350 9.928472e-01 1.878059e-06 FALSE TRUE
ENST00000537814 ENSG00000157593 No_inf pgwt_inf SLC35B2 protein_coding protein_coding 32.44206 43.07334 27.33472 2.349676 0.7725055 -0.6558678 4.1229331 8.873465 2.3357684 4.170663 1.3487820 -1.9210620 0.11221667 0.207250 0.089525 -0.117725 9.928472e-01 1.878059e-06 FALSE TRUE
ENST00000538577 ENSG00000157593 No_inf pgwt_inf SLC35B2 protein_coding protein_coding 32.44206 43.07334 27.33472 2.349676 0.7725055 -0.6558678 0.6996626 2.098988 0.0000000 2.098988 0.0000000 -7.7204068 0.01897500 0.056925 0.000000 -0.056925 1.000000e+00 1.878059e-06 FALSE TRUE
ENST00000615337 ENSG00000157593 No_inf pgwt_inf SLC35B2 protein_coding protein_coding 32.44206 43.07334 27.33472 2.349676 0.7725055 -0.6558678 4.3824923 2.635700 3.0992976 1.865911 1.8946467 0.2329394 0.14964167 0.060825 0.112300 0.051475 9.928472e-01 1.878059e-06 FALSE TRUE
MSTRG.24746.10 ENSG00000157593 No_inf pgwt_inf SLC35B2 protein_coding   32.44206 43.07334 27.33472 2.349676 0.7725055 -0.6558678 3.2307526 0.000000 7.0348549 0.000000 1.3579196 9.4604262 0.11704167 0.000000 0.253750 0.253750 1.878059e-06 1.878059e-06 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000157593 E001 0.000000       6 44254096 44254100 5 -      
ENSG00000157593 E002 0.000000       6 44254101 44254101 1 -      
ENSG00000157593 E003 12.876070 0.0013818541 4.007857e-02 0.218867525 6 44254102 44254205 104 - 1.004 1.183 0.649
ENSG00000157593 E004 240.461308 0.0017873620 3.697899e-04 0.008311036 6 44254206 44255368 1163 - 2.325 2.387 0.206
ENSG00000157593 E005 56.804971 0.0002999373 2.434387e-02 0.162678607 6 44255369 44255568 200 - 1.794 1.715 -0.267
ENSG00000157593 E006 24.076860 0.0007399432 4.551657e-01 0.751475205 6 44255569 44255644 76 - 1.407 1.368 -0.134
ENSG00000157593 E007 16.955696 0.0008567984 2.651874e-01 0.593256563 6 44256342 44256406 65 - 1.283 1.211 -0.254
ENSG00000157593 E008 17.709320 0.0008020421 3.024549e-01 0.629478963 6 44256407 44256492 86 - 1.296 1.231 -0.229
ENSG00000157593 E009 7.361818 0.0075706781 1.040054e-01 0.371573734 6 44256493 44256496 4 - 1.004 0.841 -0.614
ENSG00000157593 E010 24.858137 0.0008147202 1.349270e-01 0.425821044 6 44256685 44256878 194 - 1.447 1.365 -0.283
ENSG00000157593 E011 1.142242 0.0107779140 3.874749e-05 0.001343533 6 44256879 44256891 13 - 0.605 0.000 -12.351
ENSG00000157593 E012 1.228200 0.0677577798 5.254564e-01 0.795868054 6 44257182 44257399 218 - 0.400 0.299 -0.614
ENSG00000157593 E013 8.315590 0.0266719997 7.121472e-01 0.892952238 6 44257400 44257571 172 - 0.977 0.940 -0.136
ENSG00000157593 E014 1.833703 0.0104196858 2.748160e-01 0.602776159 6 44257769 44257890 122 - 0.534 0.378 -0.807

Help

Please Click HERE to learn more details about the results from DEXseq.