ENSG00000159685

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000290913 ENSG00000159685 No_inf pgwt_inf CHCHD6 protein_coding protein_coding 10.39535 6.603737 13.0395 0.5348479 1.714714 0.9804572 5.8804413 2.7932746 6.5753677 1.0858118 0.4548920 1.2321509 0.56551667 0.418650 0.517775 0.099125 0.992847247 0.002804064 FALSE TRUE
ENST00000510044 ENSG00000159685 No_inf pgwt_inf CHCHD6 protein_coding protein_coding_CDS_not_defined 10.39535 6.603737 13.0395 0.5348479 1.714714 0.9804572 1.4968096 0.0000000 3.4581961 0.0000000 0.6688618 8.4380417 0.11950833 0.000000 0.258775 0.258775 0.002804064 0.002804064   FALSE
ENST00000514908 ENSG00000159685 No_inf pgwt_inf CHCHD6 protein_coding protein_coding_CDS_not_defined 10.39535 6.603737 13.0395 0.5348479 1.714714 0.9804572 0.1542794 0.0000000 0.4628382 0.0000000 0.4628382 5.5632747 0.01700000 0.000000 0.051000 0.051000 1.000000000 0.002804064 FALSE TRUE
MSTRG.20666.10 ENSG00000159685 No_inf pgwt_inf CHCHD6 protein_coding   10.39535 6.603737 13.0395 0.5348479 1.714714 0.9804572 0.6759343 0.9480429 1.0797601 0.4299470 0.8107086 0.1858485 0.07651667 0.150200 0.079350 -0.070850 0.992847247 0.002804064 TRUE FALSE
MSTRG.20666.3 ENSG00000159685 No_inf pgwt_inf CHCHD6 protein_coding   10.39535 6.603737 13.0395 0.5348479 1.714714 0.9804572 0.5022049 1.1112926 0.3953222 1.1112926 0.3953222 -1.4680219 0.06196667 0.163250 0.022650 -0.140600 1.000000000 0.002804064 FALSE TRUE
MSTRG.20666.9 ENSG00000159685 No_inf pgwt_inf CHCHD6 protein_coding   10.39535 6.603737 13.0395 0.5348479 1.714714 0.9804572 1.0327734 1.3118154 0.0000000 0.7703979 0.0000000 -7.0463769 0.10405000 0.204925 0.000000 -0.204925 0.913639338 0.002804064   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000159685 E001 0.0000000       3 126704240 126704240 1 +      
ENSG00000159685 E002 0.0000000       3 126704241 126704242 2 +      
ENSG00000159685 E003 3.2897426 0.083473490 0.331683217 0.65536604 3 126704243 126704399 157 + 0.559 0.709 0.650
ENSG00000159685 E004 3.9535615 0.005509838 0.975314201 0.99574026 3 126727078 126727186 109 + 0.685 0.679 -0.028
ENSG00000159685 E005 1.2895274 0.010508135 0.270024950 0.59804516 3 126730561 126730563 3 + 0.411 0.227 -1.198
ENSG00000159685 E006 2.3676986 0.006661888 0.429919977 0.73327274 3 126730564 126730630 67 + 0.559 0.434 -0.613
ENSG00000159685 E007 5.9801949 0.002467860 0.880684743 0.96229274 3 126733078 126733222 145 + 0.842 0.812 -0.116
ENSG00000159685 E008 0.2450383 0.016369004 0.573320731   3 126780340 126780430 91 + 0.070 0.128 0.972
ENSG00000159685 E009 0.2450383 0.016369004 0.573320731   3 126852644 126852646 3 + 0.070 0.128 0.972
ENSG00000159685 E010 5.3585345 0.002718353 0.543731413 0.80742191 3 126852647 126852730 84 + 0.819 0.737 -0.328
ENSG00000159685 E011 0.0000000       3 126854864 126854948 85 +      
ENSG00000159685 E012 4.9532542 0.028156274 0.430977848 0.73398786 3 126914680 126914750 71 + 0.730 0.812 0.328
ENSG00000159685 E013 0.1139502 0.012323752 1.000000000   3 126935096 126935123 28 + 0.070 0.000 -8.555
ENSG00000159685 E014 0.0000000       3 126935124 126935186 63 +      
ENSG00000159685 E015 0.6064635 0.221446391 0.805494155   3 126949258 126949879 622 + 0.183 0.227 0.387
ENSG00000159685 E016 0.4907820 0.016010116 0.479748375   3 126953025 126953184 160 + 0.130 0.227 0.972
ENSG00000159685 E017 0.7543346 0.109519561 0.106188711 0.37623533 3 126953346 126953398 53 + 0.130 0.375 1.972
ENSG00000159685 E018 0.6215081 0.015468668 0.216055385   3 126956945 126957009 65 + 0.130 0.307 1.557
ENSG00000159685 E019 2.2362661 0.006734909 0.248139711 0.57512857 3 126957010 126957196 187 + 0.559 0.375 -0.935
ENSG00000159685 E020 1.7126039 0.008527684 0.001209258 0.02072132 3 126957197 126957332 136 + 0.559 0.000 -12.462
ENSG00000159685 E021 3.9898085 0.003802941 0.424276719 0.72925377 3 126957416 126957424 9 + 0.653 0.737 0.350
ENSG00000159685 E022 8.6151806 0.002365559 0.851136546 0.95127026 3 126957425 126957551 127 + 0.981 0.949 -0.119
ENSG00000159685 E023 0.0000000       3 126957552 126957933 382 +      
ENSG00000159685 E024 6.2409742 0.006841776 0.806918179 0.93400036 3 126960196 126960420 225 + 0.842 0.856 0.054

Help

Please Click HERE to learn more details about the results from DEXseq.