ENSG00000160310

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000355680 ENSG00000160310 No_inf pgwt_inf PRMT2 protein_coding protein_coding 45.19944 31.86679 54.74652 1.537652 0.4162377 0.7805244 4.7965390 1.8441110 5.585204 1.1188034 1.9066263 1.5934630 0.1002917 0.053700 0.101725 0.048025 0.9928472467 0.0003583189 FALSE  
ENST00000397628 ENSG00000160310 No_inf pgwt_inf PRMT2 protein_coding protein_coding 45.19944 31.86679 54.74652 1.537652 0.4162377 0.7805244 12.9710995 6.5384754 19.568102 1.0178100 2.2849660 1.5800099 0.2728583 0.202025 0.357025 0.155000 0.9584732080 0.0003583189 FALSE  
ENST00000397638 ENSG00000160310 No_inf pgwt_inf PRMT2 protein_coding protein_coding 45.19944 31.86679 54.74652 1.537652 0.4162377 0.7805244 2.9486284 2.2881202 3.776646 1.3382185 2.7776481 0.7204663 0.0694500 0.078425 0.069150 -0.009275 1.0000000000 0.0003583189 FALSE  
ENST00000455177 ENSG00000160310 No_inf pgwt_inf PRMT2 protein_coding protein_coding 45.19944 31.86679 54.74652 1.537652 0.4162377 0.7805244 4.3571373 0.7243646 4.816245 0.7243646 2.9996010 2.7163327 0.0834750 0.020725 0.088250 0.067525 0.9928472467 0.0003583189 FALSE  
ENST00000458387 ENSG00000160310 No_inf pgwt_inf PRMT2 protein_coding protein_coding 45.19944 31.86679 54.74652 1.537652 0.4162377 0.7805244 0.7507413 2.1139010 0.000000 0.2929266 0.0000000 -7.7305727 0.0231500 0.066500 0.000000 -0.066500 0.0003583189 0.0003583189 FALSE  
ENST00000481861 ENSG00000160310 No_inf pgwt_inf PRMT2 protein_coding retained_intron 45.19944 31.86679 54.74652 1.537652 0.4162377 0.7805244 13.0467574 12.2796469 13.935827 0.4699051 0.5691072 0.1823900 0.3037000 0.386150 0.254675 -0.131475 0.9742964425 0.0003583189 FALSE  
ENST00000486520 ENSG00000160310 No_inf pgwt_inf PRMT2 protein_coding retained_intron 45.19944 31.86679 54.74652 1.537652 0.4162377 0.7805244 2.1206039 2.7482018 2.099245 0.2406624 0.2058074 -0.3870014 0.0518750 0.086200 0.038425 -0.047775 0.9295208195 0.0003583189 TRUE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000160310 E001 0.3599157 0.0166118732 7.983483e-01   21 46635595 46635614 20 + 0.152 0.110 -0.542
ENSG00000160310 E002 0.6212832 0.0143962453 4.256939e-01   21 46635615 46635641 27 + 0.152 0.270 1.043
ENSG00000160310 E003 0.9636373 0.0123745299 7.925351e-01 0.9285586415 21 46635642 46635649 8 + 0.311 0.270 -0.279
ENSG00000160310 E004 1.0945004 0.0118579492 8.889111e-01 0.9656920437 21 46635650 46635652 3 + 0.311 0.332 0.136
ENSG00000160310 E005 1.8312677 0.0076925324 7.257891e-01 0.8995675312 21 46635653 46635671 19 + 0.427 0.478 0.265
ENSG00000160310 E006 1.8312677 0.0076925324 7.257891e-01 0.8995675312 21 46635672 46635673 2 + 0.427 0.478 0.265
ENSG00000160310 E007 3.4193090 0.0042242560 6.503756e-01 0.8628392053 21 46635674 46635680 7 + 0.616 0.675 0.252
ENSG00000160310 E008 12.8289081 0.0011804586 7.272929e-02 0.3063482767 21 46635681 46635763 83 + 1.200 1.054 -0.522
ENSG00000160310 E009 4.2846879 0.0033912271 4.477939e-01 0.7461982272 21 46635764 46636438 675 + 0.678 0.769 0.376
ENSG00000160310 E010 1.7001212 0.1379707109 9.151364e-01 0.9749137758 21 46636439 46636443 5 + 0.427 0.435 0.044
ENSG00000160310 E011 4.8757988 0.0094136609 7.288320e-01 0.9010847633 21 46636444 46636547 104 + 0.748 0.790 0.169
ENSG00000160310 E012 18.0542399 0.0079389087 1.864555e-02 0.1381984215 21 46636896 46636990 95 + 1.352 1.169 -0.643
ENSG00000160310 E013 1.4883864 0.0273181371 2.796691e-01 0.6078331324 21 46643286 46643534 249 + 0.311 0.478 0.943
ENSG00000160310 E014 24.8705761 0.0005580867 1.829828e-03 0.0283615291 21 46643535 46643639 105 + 1.487 1.300 -0.647
ENSG00000160310 E015 12.3244806 0.0015814300 5.524168e-01 0.8122294234 21 46644306 46644310 5 + 1.145 1.096 -0.174
ENSG00000160310 E016 15.2121411 0.0010097959 3.634963e-02 0.2070891481 21 46644311 46644342 32 + 1.273 1.116 -0.559
ENSG00000160310 E017 42.7044386 0.0003332057 1.222227e-03 0.0208859433 21 46644343 46644488 146 + 1.700 1.553 -0.500
ENSG00000160310 E018 0.1141751 0.0112333471 7.378364e-01   21 46648318 46648457 140 + 0.082 0.000 -9.779
ENSG00000160310 E019 30.2676189 0.0005080199 1.757896e-02 0.1337357847 21 46648458 46648507 50 + 1.547 1.419 -0.440
ENSG00000160310 E020 38.9964953 0.0004012617 5.882662e-01 0.8317008117 21 46648508 46648619 112 + 1.612 1.586 -0.086
ENSG00000160310 E021 0.1311489 0.0123010499 3.894133e-01   21 46649513 46649574 62 + 0.000 0.110 9.475
ENSG00000160310 E022 44.1571526 0.0003214988 9.555333e-02 0.3556934212 21 46649575 46649739 165 + 1.685 1.612 -0.250
ENSG00000160310 E023 4.6899188 0.0031077552 4.322539e-01 0.7349036984 21 46649740 46649920 181 + 0.794 0.700 -0.378
ENSG00000160310 E024 2.9609935 0.0048498760 2.415526e-01 0.5675840286 21 46651806 46652318 513 + 0.518 0.675 0.699
ENSG00000160310 E025 1.7184679 0.0085074274 5.599920e-01 0.8160682226 21 46652845 46652952 108 + 0.391 0.478 0.458
ENSG00000160310 E026 30.7138415 0.0019727108 1.091722e-05 0.0004592327 21 46656823 46658744 1922 + 1.372 1.615 0.832
ENSG00000160310 E027 39.9356040 0.0003733321 3.737566e-01 0.6913685045 21 46658745 46658920 176 + 1.591 1.632 0.140
ENSG00000160310 E028 121.3728594 0.0002495668 5.828168e-05 0.0018880720 21 46658921 46660656 1736 + 2.037 2.138 0.336
ENSG00000160310 E029 22.6448947 0.0120326901 7.565331e-01 0.9135046353 21 46660833 46660962 130 + 1.384 1.358 -0.088
ENSG00000160310 E030 12.2606239 0.0011448902 4.050331e-03 0.0501864626 21 46660963 46661799 837 + 0.999 1.232 0.839
ENSG00000160310 E031 10.1013845 0.0014392866 2.311044e-01 0.5568369994 21 46661800 46661936 137 + 1.089 0.983 -0.390
ENSG00000160310 E032 14.1948301 0.0011251252 9.534631e-01 0.9886103482 21 46663383 46663554 172 + 1.182 1.178 -0.015
ENSG00000160310 E033 40.8555627 0.0003299272 1.809396e-01 0.4937472616 21 46664295 46665124 830 + 1.591 1.652 0.208

Help

Please Click HERE to learn more details about the results from DEXseq.