ENSG00000160949

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000409379 ENSG00000160949 No_inf pgwt_inf TONSL protein_coding protein_coding 7.401597 7.530709 8.011287 0.173171 0.2723432 0.08913358 4.9241011 4.1962164 6.0939366 0.4111610 0.26471378 0.5372169 0.6668083 0.558975 0.764225 0.205250 0.96801093 0.02410263 FALSE TRUE
ENST00000497613 ENSG00000160949 No_inf pgwt_inf TONSL protein_coding retained_intron 7.401597 7.530709 8.011287 0.173171 0.2723432 0.08913358 1.2852319 1.6936883 1.2651549 0.1739794 0.05354141 -0.4179889 0.1732833 0.225925 0.157825 -0.068100 0.99284725 0.02410263 TRUE TRUE
MSTRG.28376.3 ENSG00000160949 No_inf pgwt_inf TONSL protein_coding   7.401597 7.530709 8.011287 0.173171 0.2723432 0.08913358 0.6045594 0.1687429 0.6521955 0.1687429 0.37884360 1.8893716 0.0800500 0.021000 0.077950 0.056950 0.99284725 0.02410263 TRUE TRUE
MSTRG.28376.4 ENSG00000160949 No_inf pgwt_inf TONSL protein_coding   7.401597 7.530709 8.011287 0.173171 0.2723432 0.08913358 0.5877050 1.4720613 0.0000000 0.3355231 0.00000000 -7.2114613 0.0798500 0.194125 0.000000 -0.194125 0.02410263 0.02410263 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000160949 E001 0.7370458 0.0136932440 0.9973506925 1.00000000 8 144428775 144428872 98 - 0.238 0.240 0.011
ENSG00000160949 E002 18.1977946 0.0048961334 0.3919079922 0.70553743 8 144428873 144429336 464 - 1.312 1.254 -0.202
ENSG00000160949 E003 1.1824056 0.0109736962 0.0009895777 0.01783135 8 144430334 144430403 70 - 0.000 0.507 12.202
ENSG00000160949 E004 12.6897827 0.0079555386 0.6290471995 0.85152998 8 144430404 144430537 134 - 1.112 1.155 0.151
ENSG00000160949 E005 7.6716186 0.0350301738 0.4644897026 0.75733568 8 144431078 144431151 74 - 0.979 0.897 -0.311
ENSG00000160949 E006 14.3323210 0.0231043861 0.8658077692 0.95728532 8 144432285 144432460 176 - 1.194 1.176 -0.062
ENSG00000160949 E007 10.3783076 0.0020745279 0.0107352447 0.09713872 8 144432461 144433587 1127 - 0.920 1.147 0.832
ENSG00000160949 E008 13.6461686 0.0009876278 0.7612994416 0.91534567 8 144433588 144433759 172 - 1.151 1.176 0.089
ENSG00000160949 E009 18.9140657 0.0008439830 0.8558341468 0.95334285 8 144433978 144434279 302 - 1.291 1.305 0.049
ENSG00000160949 E010 6.9543292 0.0422992667 0.3082375436 0.63462358 8 144434811 144434889 79 - 0.820 0.959 0.532
ENSG00000160949 E011 9.9787218 0.0017740050 0.2726469829 0.60088779 8 144435017 144435170 154 - 1.087 0.993 -0.342
ENSG00000160949 E012 7.3285740 0.0319809306 0.6826340532 0.87847638 8 144435474 144435550 77 - 0.945 0.897 -0.182
ENSG00000160949 E013 32.8738381 0.0066264952 0.9880526086 1.00000000 8 144435658 144436418 761 - 1.527 1.531 0.011
ENSG00000160949 E014 7.3811651 0.0021148348 0.7871421392 0.92627592 8 144436558 144436681 124 - 0.907 0.935 0.107
ENSG00000160949 E015 5.7974355 0.0123561224 0.6753782998 0.87479159 8 144436757 144436821 65 - 0.804 0.854 0.196
ENSG00000160949 E016 8.6460852 0.0302960694 0.5328122067 0.80050005 8 144436822 144436920 99 - 0.945 1.015 0.259
ENSG00000160949 E017 6.2356243 0.0163979197 0.7084704984 0.89140859 8 144437027 144437099 73 - 0.880 0.839 -0.159
ENSG00000160949 E018 3.5859348 0.0042780678 0.5745139443 0.82424275 8 144438471 144438560 90 - 0.620 0.693 0.311
ENSG00000160949 E019 0.7189579 0.0143461956 0.4165170362 0.72355600 8 144438653 144438735 83 - 0.296 0.174 -0.989
ENSG00000160949 E020 6.8733451 0.0023763186 0.9914868557 1.00000000 8 144440021 144440210 190 - 0.894 0.897 0.011
ENSG00000160949 E021 7.9763527 0.0022626743 0.0860883148 0.33581338 8 144440351 144440476 126 - 1.032 0.869 -0.610
ENSG00000160949 E022 9.0167295 0.0016882854 0.4043496618 0.71467642 8 144440718 144440870 153 - 0.957 1.035 0.289
ENSG00000160949 E023 2.3396592 0.0482632924 0.8176196954 0.93749534 8 144440871 144440965 95 - 0.504 0.539 0.163
ENSG00000160949 E024 7.5230854 0.0529526540 0.5807227025 0.82674831 8 144440966 144441111 146 - 0.894 0.960 0.249
ENSG00000160949 E025 5.9873903 0.0024143830 0.6760578544 0.87510231 8 144441112 144442036 925 - 0.866 0.823 -0.166
ENSG00000160949 E026 6.2539010 0.1027756785 0.1992287862 0.51715121 8 144442037 144442151 115 - 0.956 0.753 -0.785
ENSG00000160949 E027 0.8836693 0.1072459264 0.2969950914 0.62473860 8 144442152 144442240 89 - 0.173 0.348 1.333
ENSG00000160949 E028 9.6520868 0.0014901739 0.5802030241 0.82664105 8 144442241 144442412 172 - 1.051 1.004 -0.172
ENSG00000160949 E029 1.1467560 0.0131534369 0.0891195866 0.34260282 8 144442413 144442676 264 - 0.173 0.435 1.819
ENSG00000160949 E030 7.0026733 0.0049778172 0.0719551309 0.30465864 8 144442677 144442806 130 - 0.990 0.807 -0.699
ENSG00000160949 E031 1.2281980 0.0129155741 0.9984579826 1.00000000 8 144442807 144442856 50 - 0.346 0.348 0.011
ENSG00000160949 E032 5.9076612 0.0436491084 0.7666312279 0.91742014 8 144443138 144443321 184 - 0.820 0.854 0.131
ENSG00000160949 E033 3.0947618 0.0067971226 0.5479733898 0.80982476 8 144443882 144443959 78 - 0.566 0.647 0.359
ENSG00000160949 E034 1.6665540 0.0086332546 0.1084818473 0.38019854 8 144443960 144444024 65 - 0.536 0.297 -1.311
ENSG00000160949 E035 1.7019068 0.0744743401 0.6519724849 0.86380804 8 144444180 144444275 96 - 0.470 0.394 -0.404
ENSG00000160949 E036 0.6402162 0.0512159034 0.1811237115 0.49401006 8 144444390 144444440 51 - 0.095 0.297 2.011

Help

Please Click HERE to learn more details about the results from DEXseq.