ENSG00000161642

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000338010 ENSG00000161642 No_inf pgwt_inf ZNF385A protein_coding protein_coding 16.72321 10.18264 21.39713 0.3485669 1.712017 1.070563 0.9650961 2.1725207 0.7227675 1.4086638 0.7227675 -1.5745680 0.08610833 0.219075 0.039250 -0.179825 0.992847247 0.005676278 FALSE TRUE
ENST00000352268 ENSG00000161642 No_inf pgwt_inf ZNF385A protein_coding protein_coding 16.72321 10.18264 21.39713 0.3485669 1.712017 1.070563 2.4141381 2.4356844 0.0000000 1.4380938 0.0000000 -7.9340944 0.16340000 0.242100 0.000000 -0.242100 0.929918089 0.005676278 FALSE TRUE
ENST00000394313 ENSG00000161642 No_inf pgwt_inf ZNF385A protein_coding protein_coding 16.72321 10.18264 21.39713 0.3485669 1.712017 1.070563 10.9107945 2.1925046 17.3763997 0.4113466 1.4636132 2.9807423 0.58454167 0.219475 0.812675 0.593200 0.005676278 0.005676278 FALSE TRUE
ENST00000549937 ENSG00000161642 No_inf pgwt_inf ZNF385A protein_coding protein_coding 16.72321 10.18264 21.39713 0.3485669 1.712017 1.070563 0.4594384 0.8107006 0.4436802 0.4684642 0.3062032 -0.8551801 0.03451667 0.075200 0.022125 -0.053075 0.992847247 0.005676278 FALSE FALSE
ENST00000550779 ENSG00000161642 No_inf pgwt_inf ZNF385A protein_coding nonsense_mediated_decay 16.72321 10.18264 21.39713 0.3485669 1.712017 1.070563 0.4532217 1.3596652 0.0000000 1.3596652 0.0000000 -7.0976795 0.04160000 0.124800 0.000000 -0.124800 0.992847247 0.005676278 TRUE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000161642 E001 0.1139502 0.0111403732 1.000000000   12 54369133 54369134 2 - 0.063 0.000 -9.278
ENSG00000161642 E002 0.2285450 0.0154140538 0.771109832   12 54369135 54369135 1 - 0.119 0.000 -12.282
ENSG00000161642 E003 0.3427201 0.0157139954 0.430365532   12 54369136 54369139 4 - 0.168 0.000 -12.792
ENSG00000161642 E004 0.9140659 0.0129435316 0.046968155 0.23898701 12 54369140 54369152 13 - 0.353 0.000 -13.944
ENSG00000161642 E005 75.9810119 0.0002475498 0.004777535 0.05637258 12 54369153 54369877 725 - 1.829 1.912 0.279
ENSG00000161642 E006 15.7669061 0.0047409443 0.065004220 0.28783168 12 54369878 54370161 284 - 1.147 1.286 0.493
ENSG00000161642 E007 25.9101277 0.0012290833 0.522102622 0.79405070 12 54370162 54370486 325 - 1.390 1.425 0.120
ENSG00000161642 E008 12.9233133 0.0011252620 0.438918614 0.73999398 12 54370626 54370721 96 - 1.137 1.068 -0.250
ENSG00000161642 E009 11.2115148 0.0013449566 0.860421107 0.95507865 12 54370927 54371005 79 - 1.055 1.068 0.045
ENSG00000161642 E010 5.7860007 0.0045447032 0.209987465 0.53101596 12 54371006 54371023 18 - 0.757 0.896 0.546
ENSG00000161642 E011 8.8553844 0.0114162111 0.539728492 0.80486152 12 54371024 54371096 73 - 0.947 1.007 0.224
ENSG00000161642 E012 4.9302417 0.0049504426 0.143616958 0.43835919 12 54371473 54371490 18 - 0.802 0.608 -0.805
ENSG00000161642 E013 8.7877743 0.0016678947 0.710477147 0.89246326 12 54371491 54371582 92 - 0.977 0.936 -0.150
ENSG00000161642 E014 8.4619537 0.0023656614 0.906542374 0.97241288 12 54371583 54371641 59 - 0.947 0.955 0.031
ENSG00000161642 E015 4.5885623 0.0032042747 0.229800764 0.55531698 12 54371642 54371642 1 - 0.768 0.608 -0.672
ENSG00000161642 E016 6.6959601 0.0021960200 0.093892938 0.35237350 12 54371643 54371683 41 - 0.915 0.716 -0.782
ENSG00000161642 E017 4.6683154 0.0043499350 0.039460865 0.21696963 12 54371684 54371715 32 - 0.802 0.517 -1.220
ENSG00000161642 E018 0.2285450 0.0154140538 0.771109832   12 54372894 54372913 20 - 0.119 0.000 -12.282
ENSG00000161642 E019 0.8337999 0.0135870346 0.982607122 0.99861552 12 54372914 54373031 118 - 0.252 0.246 -0.039
ENSG00000161642 E020 13.6425081 0.0014364994 0.488565534 0.77351973 12 54373973 54374135 163 - 1.157 1.095 -0.220
ENSG00000161642 E021 11.0678732 0.0437775415 0.280944878 0.60900074 12 54375844 54375954 111 - 1.011 1.134 0.444
ENSG00000161642 E022 0.1138060 0.0113350037 1.000000000   12 54379066 54379189 124 - 0.063 0.000 -11.384
ENSG00000161642 E023 0.0000000       12 54381298 54381447 150 -      
ENSG00000161642 E024 11.3819544 0.0135811945 0.029046065 0.18038599 12 54384428 54384560 133 - 1.127 0.896 -0.851
ENSG00000161642 E025 3.7533191 0.0041289414 0.185717533 0.49958941 12 54384561 54384564 4 - 0.706 0.517 -0.833
ENSG00000161642 E026 6.9652485 0.0023197193 0.001271254 0.02155407 12 54384565 54384699 135 - 0.969 0.565 -1.638
ENSG00000161642 E027 1.5175156 0.0091017724 0.255492768 0.58262907 12 54384700 54384789 90 - 0.436 0.246 -1.177
ENSG00000161642 E028 0.9639425 0.0124676525 0.606868662 0.84105153 12 54384859 54385002 144 - 0.252 0.332 0.546
ENSG00000161642 E029 0.2456901 0.0163664014 0.482155870   12 54385235 54385264 30 - 0.063 0.140 1.283
ENSG00000161642 E030 0.0000000       12 54385673 54385768 96 -      
ENSG00000161642 E031 0.2453240 0.0162556529 0.482429207   12 54391235 54391298 64 - 0.063 0.140 1.283

Help

Please Click HERE to learn more details about the results from DEXseq.