ENSG00000161791

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000335154 ENSG00000161791 No_inf pgwt_inf FMNL3 protein_coding protein_coding 27.99898 17.30197 34.2502 1.472235 0.9847768 0.9847641 6.664136 1.1491939 9.710142 1.1491939 1.022050 3.0678555 0.21041667 0.066025 0.283000 0.216975 2.769516e-01 5.090355e-05 FALSE TRUE
ENST00000352151 ENSG00000161791 No_inf pgwt_inf FMNL3 protein_coding protein_coding 27.99898 17.30197 34.2502 1.472235 0.9847768 0.9847641 7.800993 1.9825330 11.637259 1.2302723 1.915157 2.5473149 0.25262500 0.109925 0.344075 0.234150 8.346784e-01 5.090355e-05 FALSE TRUE
ENST00000549137 ENSG00000161791 No_inf pgwt_inf FMNL3 protein_coding retained_intron 27.99898 17.30197 34.2502 1.472235 0.9847768 0.9847641 3.476488 2.4567084 3.264151 1.0885305 1.910275 0.4085336 0.12077500 0.129825 0.091100 -0.038725 9.928472e-01 5.090355e-05 FALSE TRUE
MSTRG.6475.1 ENSG00000161791 No_inf pgwt_inf FMNL3 protein_coding   27.99898 17.30197 34.2502 1.472235 0.9847768 0.9847641 1.733301 5.1999036 0.000000 1.1748558 0.000000 -9.0251129 0.10372500 0.311175 0.000000 -0.311175 5.090355e-05 5.090355e-05 FALSE TRUE
MSTRG.6475.11 ENSG00000161791 No_inf pgwt_inf FMNL3 protein_coding   27.99898 17.30197 34.2502 1.472235 0.9847768 0.9847641 2.002697 1.0051410 2.543479 1.0051410 1.540658 1.3307843 0.06958333 0.051750 0.078075 0.026325 9.928472e-01 5.090355e-05 FALSE TRUE
MSTRG.6475.12 ENSG00000161791 No_inf pgwt_inf FMNL3 protein_coding   27.99898 17.30197 34.2502 1.472235 0.9847768 0.9847641 1.915376 0.7098777 4.302880 0.7098777 1.264115 2.5828278 0.06107500 0.036550 0.123975 0.087425 6.122694e-01 5.090355e-05 FALSE TRUE
MSTRG.6475.6 ENSG00000161791 No_inf pgwt_inf FMNL3 protein_coding   27.99898 17.30197 34.2502 1.472235 0.9847768 0.9847641 2.758800 3.3492618 0.000000 1.2921934 0.000000 -8.3920004 0.11625833 0.198625 0.000000 -0.198625 1.406562e-01 5.090355e-05 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000161791 E001 0.4740403 0.5063178856 1.000000000   12 49636499 49636518 20 - 0.186 0.126 -0.670
ENSG00000161791 E002 44.9023555 0.0003001085 0.023564214 0.15952724 12 49636519 49637941 1423 - 1.608 1.708 0.340
ENSG00000161791 E003 32.3431788 0.0004395086 0.033212548 0.19561981 12 49637942 49638520 579 - 1.465 1.576 0.379
ENSG00000161791 E004 27.4214480 0.0034637041 0.030167066 0.18513595 12 49638521 49639002 482 - 1.387 1.518 0.451
ENSG00000161791 E005 152.4948682 0.0008983769 0.004325007 0.05267273 12 49639003 49644739 5737 - 2.145 2.216 0.238
ENSG00000161791 E006 10.7887311 0.0013457874 0.807743605 0.93451706 12 49644740 49644919 180 - 1.068 1.045 -0.085
ENSG00000161791 E007 1.6829666 0.0092715505 0.928749514 0.98015705 12 49644920 49644930 11 - 0.416 0.428 0.067
ENSG00000161791 E008 2.1732380 0.0095322148 0.707704936 0.89104723 12 49644931 49644952 22 - 0.472 0.525 0.263
ENSG00000161791 E009 2.4020687 0.1152288774 0.947700062 0.98673583 12 49644953 49644959 7 - 0.521 0.525 0.021
ENSG00000161791 E010 10.5090178 0.0257152511 0.476559451 0.76556222 12 49644960 49645093 134 - 1.019 1.094 0.274
ENSG00000161791 E011 88.7459141 0.0001677616 0.224650947 0.54896028 12 49645094 49645697 604 - 1.926 1.963 0.124
ENSG00000161791 E012 42.6999229 0.0047612481 0.834668611 0.94471916 12 49645698 49645903 206 - 1.632 1.620 -0.043
ENSG00000161791 E013 9.4360266 0.0015548979 0.345103582 0.66652728 12 49646639 49646753 115 - 0.972 1.058 0.314
ENSG00000161791 E014 39.2744550 0.0005974584 0.458473459 0.75340464 12 49646886 49647009 124 - 1.606 1.568 -0.132
ENSG00000161791 E015 32.6337673 0.0020076493 0.808810258 0.93498762 12 49647276 49647368 93 - 1.520 1.504 -0.054
ENSG00000161791 E016 30.8486280 0.0004594795 0.343093390 0.66440943 12 49647703 49647801 99 - 1.510 1.456 -0.187
ENSG00000161791 E017 10.8944166 0.0051881116 0.755752676 0.91311701 12 49647802 49647804 3 - 1.075 1.045 -0.109
ENSG00000161791 E018 38.1700344 0.0024687759 0.992404181 1.00000000 12 49648193 49648353 161 - 1.581 1.580 -0.004
ENSG00000161791 E019 32.0186381 0.0009472974 0.018033737 0.13566412 12 49649029 49649158 130 - 1.454 1.580 0.429
ENSG00000161791 E020 22.6921047 0.0006056682 0.286790190 0.61453718 12 49649259 49649339 81 - 1.336 1.401 0.227
ENSG00000161791 E021 14.6057123 0.0009666931 0.679685390 0.87681414 12 49649470 49649538 69 - 1.194 1.160 -0.121
ENSG00000161791 E022 31.7086884 0.0017364360 0.404896258 0.71497598 12 49649691 49649925 235 - 1.520 1.471 -0.168
ENSG00000161791 E023 26.6878619 0.0010678392 0.079983141 0.32298030 12 49650676 49650878 203 - 1.468 1.359 -0.376
ENSG00000161791 E024 21.9111778 0.0090347218 0.141124621 0.43451853 12 49651168 49651292 125 - 1.387 1.275 -0.391
ENSG00000161791 E025 13.0609630 0.0011151019 0.736187791 0.90416991 12 49651382 49651450 69 - 1.147 1.117 -0.105
ENSG00000161791 E026 47.1656616 0.0042909051 0.173553535 0.48304452 12 49651933 49652209 277 - 1.696 1.623 -0.247
ENSG00000161791 E027 14.8661134 0.0009751693 0.118874327 0.39889310 12 49652210 49652212 3 - 1.232 1.106 -0.448
ENSG00000161791 E028 0.3596403 0.0167172926 1.000000000   12 49652213 49652242 30 - 0.132 0.126 -0.085
ENSG00000161791 E029 29.7387724 0.0021043411 0.242990813 0.56922367 12 49653226 49653327 102 - 1.501 1.429 -0.245
ENSG00000161791 E030 31.0377012 0.0004843424 0.643649755 0.85946554 12 49653725 49653871 147 - 1.503 1.476 -0.094
ENSG00000161791 E031 9.9390044 0.0265826914 0.763611854 0.91606800 12 49653872 49653874 3 - 1.041 1.003 -0.138
ENSG00000161791 E032 17.9390170 0.0181507340 0.111108616 0.38525855 12 49654192 49654302 111 - 1.314 1.170 -0.509
ENSG00000161791 E033 13.3477547 0.0800154183 0.454610134 0.75111838 12 49654910 49654984 75 - 1.179 1.082 -0.346
ENSG00000161791 E034 16.0569278 0.0118884281 0.413008293 0.72093115 12 49656404 49656497 94 - 1.194 1.259 0.230
ENSG00000161791 E035 17.7459975 0.0086499773 0.412386638 0.72046196 12 49656823 49656899 77 - 1.236 1.297 0.214
ENSG00000161791 E036 20.4872274 0.0040939576 0.641490310 0.85814380 12 49657082 49657190 109 - 1.333 1.297 -0.123
ENSG00000161791 E037 8.7235640 0.0672261310 0.001469497 0.02401777 12 49658442 49658594 153 - 1.106 0.605 -1.960
ENSG00000161791 E038 1.1493711 0.0656936747 0.013626437 0.11361285 12 49661735 49661965 231 - 0.132 0.526 2.722
ENSG00000161791 E039 18.3840465 0.0007921198 0.288651077 0.61612282 12 49661966 49662049 84 - 1.303 1.225 -0.272
ENSG00000161791 E040 1.0453080 0.0182877740 0.112834947 0.38831178 12 49662050 49662191 142 - 0.385 0.126 -2.085
ENSG00000161791 E041 14.9537166 0.0009238379 0.546342569 0.80889040 12 49665832 49665908 77 - 1.208 1.160 -0.173
ENSG00000161791 E042 8.3493852 0.0053217614 0.432069639 0.73473308 12 49666127 49666158 32 - 0.988 0.906 -0.308
ENSG00000161791 E043 12.4661516 0.0012637014 0.084644393 0.33293220 12 49666159 49666207 49 - 1.168 1.018 -0.545
ENSG00000161791 E044 11.8778031 0.0016073452 0.108650895 0.38049471 12 49668471 49668554 84 - 1.147 1.003 -0.520
ENSG00000161791 E045 0.3429956 0.0281302307 0.301437392   12 49688445 49688626 182 - 0.186 0.000 -9.114
ENSG00000161791 E046 16.6674801 0.0008029061 0.131738739 0.42072920 12 49707055 49707463 409 - 1.275 1.160 -0.407
ENSG00000161791 E047 0.0000000       12 49707934 49708165 232 -      

Help

Please Click HERE to learn more details about the results from DEXseq.