ENSG00000161904

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000293760 ENSG00000161904 No_inf pgwt_inf LEMD2 protein_coding protein_coding 49.02273 58.18844 47.13715 1.662465 0.6353114 -0.30381 20.497063 11.685557 24.777782 0.7494857 1.8791204 1.0836686 0.44345000 0.200500 0.525925 0.325425 1.709017e-01 9.551375e-07 FALSE TRUE
ENST00000421671 ENSG00000161904 No_inf pgwt_inf LEMD2 protein_coding nonsense_mediated_decay 49.02273 58.18844 47.13715 1.662465 0.6353114 -0.30381 8.469488 7.908586 10.606340 1.3331465 1.6093529 0.4229717 0.17485833 0.137275 0.225650 0.088375 9.928472e-01 9.551375e-07 FALSE TRUE
ENST00000506578 ENSG00000161904 No_inf pgwt_inf LEMD2 protein_coding protein_coding 49.02273 58.18844 47.13715 1.662465 0.6353114 -0.30381 3.601131 10.803394 0.000000 1.1899281 0.0000000 -10.0786036 0.06150833 0.184525 0.000000 -0.184525 9.551375e-07 9.551375e-07   FALSE
ENST00000508327 ENSG00000161904 No_inf pgwt_inf LEMD2 protein_coding protein_coding 49.02273 58.18844 47.13715 1.662465 0.6353114 -0.30381 6.443213 11.141312 3.736746 0.3477230 1.3628262 -1.5735034 0.12553333 0.191800 0.078250 -0.113550 9.749545e-01 9.551375e-07 FALSE TRUE
ENST00000512368 ENSG00000161904 No_inf pgwt_inf LEMD2 protein_coding retained_intron 49.02273 58.18844 47.13715 1.662465 0.6353114 -0.30381 3.068713 5.864546 2.053756 1.9598569 0.7543171 -1.5092051 0.05862500 0.101900 0.043025 -0.058875 9.928472e-01 9.551375e-07 FALSE FALSE
MSTRG.24558.2 ENSG00000161904 No_inf pgwt_inf LEMD2 protein_coding   49.02273 58.18844 47.13715 1.662465 0.6353114 -0.30381 3.184924 3.192403 4.323413 0.3681420 0.6804132 0.4363487 0.06595833 0.054825 0.092175 0.037350 9.928472e-01 9.551375e-07 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000161904 E001 0.1315150 0.0122612231 5.407515e-01   6 33771202 33771212 11 - 0.000 0.095 9.387
ENSG00000161904 E002 1.2431574 0.0126402602 5.387787e-01 8.041839e-01 6 33771213 33771221 9 - 0.296 0.393 0.585
ENSG00000161904 E003 25.0868670 0.0062662825 1.688739e-01 4.758615e-01 6 33771222 33771431 210 - 1.461 1.372 -0.309
ENSG00000161904 E004 63.3609321 0.0011095959 3.205119e-01 6.452841e-01 6 33771432 33771658 227 - 1.827 1.790 -0.122
ENSG00000161904 E005 25.4947479 0.0007015328 4.690095e-01 7.603335e-01 6 33771659 33771696 38 - 1.398 1.442 0.154
ENSG00000161904 E006 142.0063708 0.0001368512 2.458499e-02 1.637128e-01 6 33771697 33772324 628 - 2.181 2.129 -0.174
ENSG00000161904 E007 122.5361463 0.0003877959 7.573118e-01 9.138238e-01 6 33772325 33772766 442 - 2.094 2.088 -0.020
ENSG00000161904 E008 23.2548482 0.0006043964 6.364895e-01 8.553663e-01 6 33772767 33772775 9 - 1.367 1.398 0.107
ENSG00000161904 E009 21.1307274 0.0007231751 2.073670e-01 5.278450e-01 6 33772776 33772778 3 - 1.298 1.381 0.288
ENSG00000161904 E010 2.4086459 0.0057343603 3.838592e-02 2.134445e-01 6 33776614 33776953 340 - 0.347 0.646 1.486
ENSG00000161904 E011 38.9971323 0.0003559605 5.655393e-01 8.187803e-01 6 33776954 33777011 58 - 1.585 1.614 0.100
ENSG00000161904 E012 30.5603107 0.0004614823 3.545262e-01 6.744446e-01 6 33777012 33777034 23 - 1.523 1.476 -0.161
ENSG00000161904 E013 28.6498583 0.0029571900 5.968951e-01 8.359512e-01 6 33777035 33777056 22 - 1.486 1.457 -0.098
ENSG00000161904 E014 30.5981648 0.0067883786 5.740428e-01 8.241166e-01 6 33777138 33777153 16 - 1.516 1.483 -0.115
ENSG00000161904 E015 47.3557804 0.0003240291 8.782138e-01 9.613298e-01 6 33777154 33777239 86 - 1.686 1.681 -0.015
ENSG00000161904 E016 41.0253612 0.0026942268 6.193415e-01 8.470093e-01 6 33778242 33778318 77 - 1.635 1.612 -0.077
ENSG00000161904 E017 21.2043697 0.0008317656 1.803888e-02 1.356775e-01 6 33778319 33778330 12 - 1.419 1.270 -0.516
ENSG00000161904 E018 29.4734660 0.0047904760 2.237595e-02 1.548028e-01 6 33778331 33778387 57 - 1.550 1.415 -0.467
ENSG00000161904 E019 6.1087047 0.0023355090 1.226431e-01 4.054954e-01 6 33778388 33780001 1614 - 0.752 0.921 0.659
ENSG00000161904 E020 0.4915678 0.0793412672 9.998063e-01   6 33780002 33780099 98 - 0.173 0.173 0.000
ENSG00000161904 E021 36.8966080 0.0003897055 5.155089e-02 2.523636e-01 6 33780100 33780179 80 - 1.625 1.532 -0.315
ENSG00000161904 E022 0.0000000       6 33780180 33780299 120 -      
ENSG00000161904 E023 35.7487094 0.0005187327 5.307911e-01 7.992278e-01 6 33781077 33781153 77 - 1.579 1.551 -0.099
ENSG00000161904 E024 2.4877300 0.0061704454 3.828229e-01 6.988110e-01 6 33781154 33781356 203 - 0.471 0.595 0.585
ENSG00000161904 E025 8.2076693 0.0017039993 8.165270e-04 1.536008e-02 6 33781357 33782246 890 - 0.752 1.089 1.276
ENSG00000161904 E026 30.4916171 0.0004627998 6.275824e-01 8.507920e-01 6 33784352 33784427 76 - 1.510 1.486 -0.081
ENSG00000161904 E027 118.0470160 0.0001546286 3.195764e-16 7.641907e-14 6 33784428 33786733 2306 - 1.939 2.166 0.759
ENSG00000161904 E028 23.2623663 0.0006901820 1.300976e-02 1.099914e-01 6 33786734 33786774 41 - 1.457 1.308 -0.516
ENSG00000161904 E029 10.1709599 0.0016651828 2.969540e-03 4.045189e-02 6 33786775 33786873 99 - 0.881 1.153 1.000
ENSG00000161904 E030 89.3547431 0.0030944984 2.235642e-09 2.161772e-07 6 33786874 33788380 1507 - 1.815 2.048 0.782
ENSG00000161904 E031 45.3809808 0.0003223867 5.903138e-08 4.364540e-06 6 33788381 33788774 394 - 1.776 1.538 -0.809
ENSG00000161904 E032 43.6914510 0.0012737226 4.158323e-09 3.806013e-07 6 33788775 33789203 429 - 1.775 1.500 -0.935

Help

Please Click HERE to learn more details about the results from DEXseq.