ENSG00000162222

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000316461 ENSG00000162222 No_inf pgwt_inf TTC9C protein_coding protein_coding 23.9228 23.87039 24.11029 2.476586 1.814302 0.01442138 5.2417291 3.720367 5.661289 0.2093315 0.7930209 0.6043591 0.22915833 0.162975 0.245475 0.082500 0.9928472467 0.0002840782 FALSE TRUE
ENST00000530625 ENSG00000162222 No_inf pgwt_inf TTC9C protein_coding protein_coding 23.9228 23.87039 24.11029 2.476586 1.814302 0.01442138 10.1364141 10.659775 9.206090 2.2013149 1.7024238 -0.2113029 0.42540833 0.449500 0.387625 -0.061875 0.9932366119 0.0002840782 FALSE FALSE
ENST00000532276 ENSG00000162222 No_inf pgwt_inf TTC9C protein_coding nonsense_mediated_decay 23.9228 23.87039 24.11029 2.476586 1.814302 0.01442138 2.7494407 0.000000 5.553236 0.0000000 1.9454139 9.1197805 0.10710833 0.000000 0.221325 0.221325 0.0002840782 0.0002840782   FALSE
ENST00000601045 ENSG00000162222 No_inf pgwt_inf TTC9C protein_coding retained_intron 23.9228 23.87039 24.11029 2.476586 1.814302 0.01442138 0.8337579 2.501274 0.000000 2.5012736 0.0000000 -7.9722754 0.02806667 0.084200 0.000000 -0.084200 0.9928472467 0.0002840782   FALSE
MSTRG.4855.5 ENSG00000162222 No_inf pgwt_inf TTC9C protein_coding   23.9228 23.87039 24.11029 2.476586 1.814302 0.01442138 3.2467216 5.025859 2.085156 1.0563005 0.7314207 -1.2651804 0.14310833 0.228400 0.085500 -0.142900 0.9657576836 0.0002840782   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000162222 E001 0.0000000       11 62728069 62728111 43 +      
ENSG00000162222 E002 0.2449549 0.0162340690 0.985837768   11 62728112 62728227 116 + 0.096 0.094 -0.034
ENSG00000162222 E003 0.3592742 0.0165448988 0.568356096   11 62728228 62728485 258 + 0.175 0.094 -1.034
ENSG00000162222 E004 4.0420532 0.0039951156 0.808112869 0.93465176 11 62728486 62728641 156 + 0.717 0.688 -0.122
ENSG00000162222 E005 4.1641164 0.0061587145 0.008897512 0.08601955 11 62728642 62728736 95 + 0.857 0.534 -1.356
ENSG00000162222 E006 3.5943173 0.0340745971 0.088482299 0.34136420 11 62728737 62728822 86 + 0.775 0.534 -1.034
ENSG00000162222 E007 6.9552193 0.0053248888 0.457051778 0.75280952 11 62728823 62728865 43 + 0.939 0.863 -0.288
ENSG00000162222 E008 33.8569027 0.0044004953 0.718936797 0.89685554 11 62728866 62729086 221 + 1.549 1.533 -0.055
ENSG00000162222 E009 2.9509146 0.1053781813 0.012962803 0.10969924 11 62733118 62733199 82 + 0.299 0.748 2.214
ENSG00000162222 E010 14.9481111 0.0033044225 0.390065915 0.70369874 11 62735382 62735449 68 + 1.165 1.230 0.229
ENSG00000162222 E011 21.2921369 0.0007004046 0.110336649 0.38355251 11 62735450 62735564 115 + 1.292 1.389 0.337
ENSG00000162222 E012 1.7150754 0.0688138652 0.989735248 1.00000000 11 62735565 62736243 679 + 0.437 0.430 -0.034
ENSG00000162222 E013 27.3322936 0.0065126099 0.727910310 0.90057305 11 62738288 62738490 203 + 1.462 1.441 -0.073
ENSG00000162222 E014 45.6746616 0.0003925851 0.972837238 0.99523628 11 62738491 62739947 1457 + 1.668 1.667 -0.003
ENSG00000162222 E015 2.9801049 0.0136173431 0.454376227 0.75098606 11 62739948 62739975 28 + 0.541 0.642 0.451
ENSG00000162222 E016 9.9279840 0.0015724041 0.825887834 0.94119776 11 62739976 62740293 318 + 1.048 1.028 -0.070

Help

Please Click HERE to learn more details about the results from DEXseq.