ENSG00000162695

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000357650 ENSG00000162695 No_inf pgwt_inf SLC30A7 protein_coding protein_coding 15.63853 11.8095 17.22091 0.2896176 0.6628399 0.5438295 6.816179 2.745300 8.572823 0.6111828 1.365069 1.6392431 0.4135250 0.231750 0.496525 0.264775 0.8107810754 1.81082e-05 FALSE TRUE
ENST00000370112 ENSG00000162695 No_inf pgwt_inf SLC30A7 protein_coding protein_coding 15.63853 11.8095 17.22091 0.2896176 0.6628399 0.5438295 6.925419 4.416036 7.962836 1.3186920 1.628853 0.8490776 0.4377583 0.378775 0.465850 0.087075 0.9928472467 1.81082e-05 FALSE TRUE
MSTRG.1408.4 ENSG00000162695 No_inf pgwt_inf SLC30A7 protein_coding   15.63853 11.8095 17.22091 0.2896176 0.6628399 0.5438295 1.500480 4.501440 0.000000 0.8647029 0.000000 -8.8174442 0.1259333 0.377800 0.000000 -0.377800 0.0000181082 1.81082e-05 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000162695 E001 0.3603385 1.539116e-01 9.196559e-01   1 100896076 100896089 14 + 0.145 0.115 -0.382
ENSG00000162695 E002 15.6384904 8.590423e-04 3.683696e-02 2.085673e-01 1 100896090 100896342 253 + 1.278 1.118 -0.568
ENSG00000162695 E003 11.7522080 1.156187e-03 2.508933e-01 5.779531e-01 1 100896570 100896671 102 + 1.141 1.042 -0.360
ENSG00000162695 E004 12.3335895 5.658623e-02 3.456988e-01 6.669749e-01 1 100906852 100906965 114 + 1.165 1.053 -0.404
ENSG00000162695 E005 9.9620414 5.221628e-03 1.512911e-02 1.210743e-01 1 100911063 100911150 88 + 1.122 0.885 -0.877
ENSG00000162695 E006 10.6051365 1.027810e-02 6.889827e-02 2.975281e-01 1 100912112 100912238 127 + 1.129 0.949 -0.659
ENSG00000162695 E007 10.8345884 5.176436e-03 4.090517e-02 2.214678e-01 1 100913663 100913806 144 + 1.141 0.949 -0.704
ENSG00000162695 E008 6.7032638 8.470286e-03 2.930356e-01 6.213709e-01 1 100918077 100918127 51 + 0.930 0.810 -0.460
ENSG00000162695 E009 10.7231630 1.275602e-02 7.250944e-01 8.992725e-01 1 100921706 100921841 136 + 1.082 1.042 -0.145
ENSG00000162695 E010 9.1605829 1.002947e-02 6.656621e-02 2.919937e-01 1 100961828 100961918 91 + 1.074 0.885 -0.704
ENSG00000162695 E011 15.5740274 1.434219e-02 4.761165e-04 1.019158e-02 1 100965769 100965918 150 + 1.325 1.004 -1.148
ENSG00000162695 E012 0.5882690 1.890300e-01 4.420664e-01   1 100972277 100972658 382 + 0.253 0.115 -1.382
ENSG00000162695 E013 0.2622978 2.400247e-01 1.660319e-01   1 100973207 100973274 68 + 0.000 0.206 10.628
ENSG00000162695 E014 11.6661748 1.167783e-02 5.678579e-01 8.198566e-01 1 100974810 100974902 93 + 1.122 1.065 -0.207
ENSG00000162695 E015 12.4338743 1.080473e-02 4.417653e-03 5.331110e-02 1 100974903 100975218 316 + 1.220 0.949 -0.985
ENSG00000162695 E016 500.4879692 8.341583e-05 1.930264e-13 3.348693e-11 1 100975219 100981793 6575 + 2.676 2.721 0.147

Help

Please Click HERE to learn more details about the results from DEXseq.