ENSG00000163162

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000295317 ENSG00000163162 No_inf pgwt_inf RNF149 protein_coding protein_coding 97.26178 111.7213 79.5237 2.911716 1.393447 -0.4903948 36.857058 30.86600 32.397993 1.1253855 1.3501513 0.06986371 0.38507500 0.277425 0.406950 0.129525 9.791526e-01 1.199135e-06 FALSE TRUE
ENST00000424632 ENSG00000163162 No_inf pgwt_inf RNF149 protein_coding nonsense_mediated_decay 97.26178 111.7213 79.5237 2.911716 1.393447 -0.4903948 5.341387 0.00000 8.096804 0.0000000 1.1917072 9.66298953 0.05998333 0.000000 0.101425 0.101425 1.199135e-06 1.199135e-06 TRUE TRUE
ENST00000463726 ENSG00000163162 No_inf pgwt_inf RNF149 protein_coding retained_intron 97.26178 111.7213 79.5237 2.911716 1.393447 -0.4903948 9.622199 15.22753 6.013414 1.5150691 1.2199168 -1.33897548 0.09567500 0.135725 0.075175 -0.060550 9.808533e-01 1.199135e-06   FALSE
MSTRG.16743.1 ENSG00000163162 No_inf pgwt_inf RNF149 protein_coding   97.26178 111.7213 79.5237 2.911716 1.393447 -0.4903948 7.917436 13.85086 3.792381 0.8954987 1.4313708 -1.86604191 0.07715833 0.123775 0.047000 -0.076775 6.996491e-01 1.199135e-06   FALSE
MSTRG.16743.2 ENSG00000163162 No_inf pgwt_inf RNF149 protein_coding   97.26178 111.7213 79.5237 2.911716 1.393447 -0.4903948 10.765112 16.95756 7.496653 0.3543753 0.7004572 -1.17653754 0.10823333 0.151925 0.094500 -0.057425 9.928472e-01 1.199135e-06 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000163162 E001 0.3936739 1.592972e-02 1.739074e-01   2 101271219 101271221 3 - 0.000 0.212 10.960
ENSG00000163162 E002 63.4365489 2.265681e-04 8.007946e-06 3.504615e-04 2 101271222 101271744 523 - 1.687 1.858 0.577
ENSG00000163162 E003 1.0172824 1.237658e-02 3.030948e-01 6.299217e-01 2 101272830 101272841 12 - 0.196 0.354 1.145
ENSG00000163162 E004 9.5302319 1.085046e-02 1.666987e-01 4.728236e-01 2 101272842 101272935 94 - 0.925 1.061 0.503
ENSG00000163162 E005 12.0204263 1.138163e-03 1.508424e-01 4.493822e-01 2 101272936 101273095 160 - 1.029 1.147 0.426
ENSG00000163162 E006 36.7406389 1.831904e-03 6.234166e-03 6.780310e-02 2 101273127 101273341 215 - 1.474 1.617 0.486
ENSG00000163162 E007 42.1181572 3.324082e-04 3.093530e-13 5.297521e-11 2 101273342 101274030 689 - 1.366 1.734 1.257
ENSG00000163162 E008 87.6438512 1.841016e-04 6.579243e-06 2.939947e-04 2 101274031 101274738 708 - 1.843 1.988 0.486
ENSG00000163162 E009 46.5798056 4.566572e-04 2.772122e-04 6.689131e-03 2 101274739 101275600 862 - 1.561 1.724 0.554
ENSG00000163162 E010 0.2456120 1.618564e-02 8.189310e-01   2 101275601 101275684 84 - 0.109 0.083 -0.440
ENSG00000163162 E011 0.3940400 1.591649e-02 1.739651e-01   2 101275685 101275706 22 - 0.000 0.212 12.904
ENSG00000163162 E012 0.6389948 1.424306e-02 2.960849e-01   2 101275707 101275708 2 - 0.109 0.265 1.560
ENSG00000163162 E013 21.7849123 6.327681e-04 2.061674e-03 3.108809e-02 2 101275709 101276247 539 - 1.215 1.415 0.700
ENSG00000163162 E014 368.0634119 7.732031e-05 6.092788e-02 2.780607e-01 2 101276248 101277281 1034 - 2.575 2.544 -0.100
ENSG00000163162 E015 4.6679764 3.102985e-03 1.090408e-01 3.811086e-01 2 101281493 101281858 366 - 0.617 0.811 0.801
ENSG00000163162 E016 145.4527109 1.193500e-04 2.913057e-03 3.992023e-02 2 101281859 101282057 199 - 2.200 2.124 -0.254
ENSG00000163162 E017 75.4720185 2.215799e-04 2.279355e-03 3.342592e-02 2 101286081 101286177 97 - 1.936 1.827 -0.365
ENSG00000163162 E018 14.7924313 2.564575e-03 1.668806e-03 2.649454e-02 2 101286178 101286503 326 - 1.018 1.271 0.908
ENSG00000163162 E019 19.1204228 8.892568e-04 8.939434e-03 8.629911e-02 2 101286870 101287482 613 - 1.175 1.355 0.631
ENSG00000163162 E020 5.1434717 1.462529e-02 2.934722e-01 6.219284e-01 2 101287483 101287563 81 - 0.698 0.824 0.507
ENSG00000163162 E021 7.1439523 2.125188e-02 3.044016e-01 6.311550e-01 2 101287564 101287716 153 - 0.826 0.943 0.447
ENSG00000163162 E022 6.3866960 2.264955e-03 2.881679e-01 6.158608e-01 2 101288708 101288972 265 - 0.788 0.900 0.434
ENSG00000163162 E023 70.1683759 2.180550e-04 6.908910e-02 2.978692e-01 2 101288973 101289055 83 - 1.882 1.814 -0.232
ENSG00000163162 E024 55.8140519 2.551607e-04 5.963157e-02 2.745154e-01 2 101294014 101294082 69 - 1.791 1.711 -0.268
ENSG00000163162 E025 4.2398354 3.385985e-03 6.040769e-01 8.392513e-01 2 101294083 101294662 580 - 0.673 0.733 0.252
ENSG00000163162 E026 106.6527154 1.202459e-03 6.733330e-05 2.131458e-03 2 101294931 101295181 251 - 2.095 1.967 -0.430
ENSG00000163162 E027 2.2779295 6.077696e-03 1.963085e-01 5.131089e-01 2 101307841 101308128 288 - 0.385 0.572 0.938
ENSG00000163162 E028 112.4525318 3.721191e-03 7.702211e-06 3.387569e-04 2 101308129 101308716 588 - 2.138 1.972 -0.557

Help

Please Click HERE to learn more details about the results from DEXseq.