ENSG00000163558

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000295797 ENSG00000163558 No_inf pgwt_inf PRKCI protein_coding protein_coding 6.888619 5.680538 8.099311 0.1163474 3.624103 0.5110143 3.9884478 2.838715 4.189683 0.1537782 0.3120945 0.559969 0.66803333 0.500075 0.748625 0.248550 9.638317e-01 7.986996e-05 FALSE TRUE
ENST00000483697 ENSG00000163558 No_inf pgwt_inf PRKCI protein_coding retained_intron 6.888619 5.680538 8.099311 0.1163474 3.624103 0.5110143 0.9407663 0.000000 1.603239 0.0000000 1.6032393 7.333817 0.06733333 0.000000 0.084550 0.084550 9.928472e-01 7.986996e-05   FALSE
ENST00000485837 ENSG00000163558 No_inf pgwt_inf PRKCI protein_coding retained_intron 6.888619 5.680538 8.099311 0.1163474 3.624103 0.5110143 1.1275625 2.652683 0.000000 0.2648119 0.0000000 -8.056737 0.19748333 0.465300 0.000000 -0.465300 7.986996e-05 7.986996e-05 FALSE TRUE
ENST00000488541 ENSG00000163558 No_inf pgwt_inf PRKCI protein_coding retained_intron 6.888619 5.680538 8.099311 0.1163474 3.624103 0.5110143 0.6821879 0.000000 2.046564 0.0000000 2.0465636 7.684092 0.03597500 0.000000 0.107925 0.107925 9.928472e-01 7.986996e-05   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000163558 E001 2.4029088 0.0369467305 2.023602e-01 5.214914e-01 3 170222424 170222770 347 + 0.624 0.431 -0.917
ENSG00000163558 E002 2.2735471 0.0089937816 1.036687e-01 3.709228e-01 3 170235230 170235351 122 + 0.624 0.390 -1.139
ENSG00000163558 E003 2.0281455 0.0073735397 8.395926e-02 3.313545e-01 3 170259969 170260058 90 + 0.598 0.345 -1.286
ENSG00000163558 E004 2.0428189 0.0136271961 2.223678e-01 5.465354e-01 3 170263379 170263429 51 + 0.570 0.390 -0.898
ENSG00000163558 E005 2.9439092 0.0051807297 9.787897e-01 9.972297e-01 3 170267915 170268000 86 + 0.598 0.593 -0.023
ENSG00000163558 E006 3.5497584 0.0225903821 8.414252e-01 9.475929e-01 3 170270421 170270561 141 + 0.672 0.643 -0.123
ENSG00000163558 E007 1.5537919 0.2419448988 3.761965e-01 6.936944e-01 3 170273286 170273340 55 + 0.508 0.295 -1.195
ENSG00000163558 E008 1.6211156 0.2376441436 4.916345e-01 7.752304e-01 3 170275229 170275287 59 + 0.349 0.469 0.653
ENSG00000163558 E009 0.0000000       3 170280145 170280226 82 +      
ENSG00000163558 E010 1.2277274 0.2958227899 9.365888e-01 9.827787e-01 3 170280227 170280239 13 + 0.349 0.345 -0.025
ENSG00000163558 E011 5.1370732 0.0069051361 7.440953e-01 9.080908e-01 3 170280240 170280403 164 + 0.808 0.768 -0.161
ENSG00000163558 E012 5.3488256 0.0235072691 4.091357e-01 7.181062e-01 3 170281166 170281263 98 + 0.856 0.749 -0.419
ENSG00000163558 E013 0.0000000       3 170281264 170281537 274 +      
ENSG00000163558 E014 0.0000000       3 170281610 170281881 272 +      
ENSG00000163558 E015 2.5835555 0.0061753265 8.489336e-01 9.503674e-01 3 170281882 170281968 87 + 0.540 0.565 0.114
ENSG00000163558 E016 3.3840497 0.0046692730 2.437634e-01 5.700879e-01 3 170284461 170284596 136 + 0.716 0.565 -0.651
ENSG00000163558 E017 0.2450383 0.0162002316 9.939853e-01   3 170291642 170291853 212 + 0.096 0.094 -0.023
ENSG00000163558 E018 4.0861978 0.0044393273 7.937102e-02 3.216583e-01 3 170291854 170291941 88 + 0.808 0.593 -0.898
ENSG00000163558 E019 0.1311489 0.0122780825 5.452664e-01   3 170293332 170293346 15 + 0.000 0.094 9.199
ENSG00000163558 E020 0.2628107 0.0162025800 2.466303e-01   3 170293347 170293382 36 + 0.000 0.172 10.122
ENSG00000163558 E021 6.8515054 0.0032541902 2.065950e-02 1.469951e-01 3 170293383 170293508 126 + 1.006 0.768 -0.911
ENSG00000163558 E022 4.6101756 0.0287413984 1.950583e-03 2.984111e-02 3 170295911 170295990 80 + 0.925 0.503 -1.760
ENSG00000163558 E023 6.2182126 0.0026402908 4.601671e-01 7.543830e-01 3 170297304 170297393 90 + 0.898 0.819 -0.307
ENSG00000163558 E024 5.9243273 0.0024705406 5.862618e-01 8.303538e-01 3 170298995 170299110 116 + 0.808 0.864 0.218
ENSG00000163558 E025 77.7418483 0.0002390529 1.466811e-07 9.881618e-06 3 170303040 170305981 2942 + 1.825 1.947 0.408

Help

Please Click HERE to learn more details about the results from DEXseq.