ENSG00000163738

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000325278 ENSG00000163738 No_inf pgwt_inf MTHFD2L protein_coding protein_coding 9.377294 5.038478 10.72076 1.659543 0.9075054 1.087832 1.0671783 1.2579975 1.0644587 0.48364887 0.42451829 -0.2389419 0.17880833 0.368775 0.098475 -0.270300 9.928472e-01 6.359711e-05 FALSE TRUE
ENST00000461101 ENSG00000163738 No_inf pgwt_inf MTHFD2L protein_coding protein_coding_CDS_not_defined 9.377294 5.038478 10.72076 1.659543 0.9075054 1.087832 1.0196627 1.1503181 0.8882690 0.17393640 0.30618049 -0.3693009 0.14732500 0.271225 0.089000 -0.182225 9.322479e-01 6.359711e-05   FALSE
ENST00000492183 ENSG00000163738 No_inf pgwt_inf MTHFD2L protein_coding retained_intron 9.377294 5.038478 10.72076 1.659543 0.9075054 1.087832 0.1687628 0.3503616 0.1352206 0.08231228 0.08292554 -1.3111987 0.03091667 0.076375 0.014725 -0.061650 8.714742e-01 6.359711e-05 FALSE TRUE
MSTRG.21899.12 ENSG00000163738 No_inf pgwt_inf MTHFD2L protein_coding   9.377294 5.038478 10.72076 1.659543 0.9075054 1.087832 0.4444403 1.3333210 0.0000000 1.33332096 0.00000000 -7.0696602 0.04444167 0.133325 0.000000 -0.133325 9.928472e-01 6.359711e-05 FALSE FALSE
MSTRG.21899.15 ENSG00000163738 No_inf pgwt_inf MTHFD2L protein_coding   9.377294 5.038478 10.72076 1.659543 0.9075054 1.087832 0.8207655 0.0000000 0.3829737 0.00000000 0.38297367 5.2963607 0.07715833 0.000000 0.043975 0.043975 1.000000e+00 6.359711e-05   FALSE
MSTRG.21899.16 ENSG00000163738 No_inf pgwt_inf MTHFD2L protein_coding   9.377294 5.038478 10.72076 1.659543 0.9075054 1.087832 4.1458132 0.0000000 5.9635685 0.00000000 0.60014756 9.2224492 0.35568333 0.000000 0.557000 0.557000 6.359711e-05 6.359711e-05   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000163738 E001 0.0000000       4 74114174 74114383 210 +      
ENSG00000163738 E002 0.0000000       4 74114488 74114657 170 +      
ENSG00000163738 E003 0.0000000       4 74123273 74123338 66 +      
ENSG00000163738 E004 0.0000000       4 74123339 74123343 5 +      
ENSG00000163738 E005 0.0000000       4 74123344 74123423 80 +      
ENSG00000163738 E006 0.0000000       4 74125438 74125439 2 +      
ENSG00000163738 E007 0.0000000       4 74125440 74125517 78 +      
ENSG00000163738 E008 0.0000000       4 74143393 74143467 75 +      
ENSG00000163738 E009 0.0000000       4 74158108 74158111 4 +      
ENSG00000163738 E010 0.0000000       4 74158112 74158117 6 +      
ENSG00000163738 E011 0.0000000       4 74158118 74158174 57 +      
ENSG00000163738 E012 0.0000000       4 74158175 74158281 107 +      
ENSG00000163738 E013 0.3771270 0.0169750618 2.334655e-01   4 74160055 74160088 34 + 0.067 0.234 2.086
ENSG00000163738 E014 10.3403963 0.0266747136 9.424915e-04 1.716402e-02 4 74160089 74161779 1691 + 0.888 1.223 1.223
ENSG00000163738 E015 2.2256031 0.0072066675 4.575566e-02 2.351389e-01 4 74161780 74162253 474 + 0.370 0.660 1.408
ENSG00000163738 E016 1.7003738 0.0127861109 4.234335e-01 7.286414e-01 4 74174506 74174690 185 + 0.370 0.497 0.671
ENSG00000163738 E017 1.1932356 0.0122426942 8.597115e-01 9.547781e-01 4 74175281 74175403 123 + 0.338 0.316 -0.137
ENSG00000163738 E018 0.0000000       4 74180687 74180866 180 +      
ENSG00000163738 E019 0.3420755 0.0182823803 3.375393e-01   4 74181686 74181791 106 + 0.177 0.000 -12.027
ENSG00000163738 E020 1.1305698 0.0120920988 3.833690e-02 2.132837e-01 4 74182727 74183931 1205 + 0.177 0.497 2.086
ENSG00000163738 E021 0.1316618 0.0124502268 2.466076e-01   4 74193514 74193570 57 + 0.000 0.132 11.864
ENSG00000163738 E022 2.5416657 0.0078199313 1.085769e-04 3.158307e-03 4 74194040 74195838 1799 + 0.265 0.803 2.671
ENSG00000163738 E023 1.8846076 0.0085389344 7.241530e-03 7.527391e-02 4 74199794 74199946 153 + 0.265 0.660 2.086
ENSG00000163738 E024 2.0493441 0.0994332113 6.953276e-04 1.359063e-02 4 74201263 74201370 108 + 0.177 0.751 3.201
ENSG00000163738 E025 0.0000000       4 74224068 74224147 80 +      
ENSG00000163738 E026 1.1128061 0.0486171592 1.728247e-01 4.819844e-01 4 74225302 74225394 93 + 0.223 0.445 1.407
ENSG00000163738 E027 1.6833427 0.0086223918 8.141578e-01 9.366470e-01 4 74241567 74242210 644 + 0.400 0.445 0.238
ENSG00000163738 E028 0.1145948 0.0118575301 1.000000e+00   4 74261197 74261209 13 + 0.067 0.000 -10.730
ENSG00000163738 E029 0.1139502 0.0113036662 1.000000e+00   4 74265277 74265288 12 + 0.067 0.000 -10.731
ENSG00000163738 E030 1.1409526 0.0109828946 1.132315e-02 1.007665e-01 4 74265289 74265395 107 + 0.428 0.000 -13.236
ENSG00000163738 E031 0.1308632 0.0125591296 2.463972e-01   4 74280241 74280443 203 + 0.000 0.132 11.864
ENSG00000163738 E032 4.5349754 0.0036934073 3.567460e-03 4.596655e-02 4 74281425 74281550 126 + 0.827 0.445 -1.680
ENSG00000163738 E033 0.1141751 0.0112696475 1.000000e+00   4 74288301 74288465 165 + 0.067 0.000 -10.731
ENSG00000163738 E034 0.4911578 0.0165933922 4.751210e-01   4 74293489 74293562 74 + 0.126 0.234 1.086
ENSG00000163738 E035 0.2456120 0.0163824266 5.714369e-01   4 74293563 74293675 113 + 0.067 0.132 1.086
ENSG00000163738 E036 35.6087163 0.0005473639 4.143491e-12 5.881320e-10 4 74301697 74303099 1403 + 1.622 1.350 -0.932

Help

Please Click HERE to learn more details about the results from DEXseq.