ENSG00000163960

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000296328 ENSG00000163960 No_inf pgwt_inf UBXN7 protein_coding protein_coding 10.63769 6.698854 11.95956 0.1612157 3.024883 0.8352323 5.8079363 6.477242 5.039356 0.09536220 0.09409333 -0.3615058 0.64083333 0.967625 0.483175 -0.48445 0.010559986 0.008362688 FALSE TRUE
ENST00000381887 ENSG00000163960 No_inf pgwt_inf UBXN7 protein_coding protein_coding 10.63769 6.698854 11.95956 0.1612157 3.024883 0.8352323 1.9983995 0.000000 3.050070 0.00000000 3.05007031 8.2574210 0.10913333 0.000000 0.145150 0.14515 0.993236612 0.008362688 FALSE FALSE
ENST00000429160 ENSG00000163960 No_inf pgwt_inf UBXN7 protein_coding nonsense_mediated_decay 10.63769 6.698854 11.95956 0.1612157 3.024883 0.8352323 2.2186045 0.000000 2.806097 0.00000000 0.25883100 8.1375534 0.19060833 0.000000 0.271200 0.27120 0.008362688 0.008362688 FALSE TRUE
ENST00000493566 ENSG00000163960 No_inf pgwt_inf UBXN7 protein_coding retained_intron 10.63769 6.698854 11.95956 0.1612157 3.024883 0.8352323 0.6127485 0.221612 1.064040 0.07411508 0.15210553 2.2132659 0.05941667 0.032375 0.100475 0.06810 0.979152588 0.008362688 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000163960 E001 237.863815 9.152337e-05 1.056063e-26 5.496290e-24 3 196347662 196354876 7215 - 2.299 2.428 0.431
ENSG00000163960 E002 67.261466 2.150361e-04 2.689777e-05 9.854349e-04 3 196354877 196356617 1741 - 1.906 1.762 -0.485
ENSG00000163960 E003 9.498370 3.657035e-02 3.284698e-01 6.525481e-01 3 196356618 196356846 229 - 1.079 0.964 -0.421
ENSG00000163960 E004 5.040867 8.735996e-03 9.357562e-01 9.823172e-01 3 196361844 196361923 80 - 0.786 0.773 -0.053
ENSG00000163960 E005 16.844957 8.639551e-04 9.215070e-03 8.814256e-02 3 196362294 196362687 394 - 1.342 1.157 -0.648
ENSG00000163960 E006 5.621418 2.803362e-03 6.015584e-03 6.600729e-02 3 196368028 196368155 128 - 0.963 0.655 -1.217
ENSG00000163960 E007 3.988249 3.891151e-03 1.525025e-01 4.520183e-01 3 196369421 196369511 91 - 0.786 0.607 -0.745
ENSG00000163960 E008 6.159187 2.272455e-03 8.154636e-05 2.499460e-03 3 196371896 196372042 147 - 1.040 0.607 -1.708
ENSG00000163960 E009 2.693000 5.166013e-03 6.613375e-04 1.305121e-02 3 196391813 196391837 25 - 0.768 0.287 -2.371
ENSG00000163960 E010 5.244845 2.776318e-03 2.832345e-03 3.918631e-02 3 196391838 196391925 88 - 0.950 0.607 -1.377
ENSG00000163960 E011 3.464670 4.469694e-03 2.439300e-02 1.629454e-01 3 196393554 196393580 27 - 0.786 0.493 -1.275
ENSG00000163960 E012 3.841880 3.740650e-03 4.753952e-02 2.404195e-01 3 196393581 196393619 39 - 0.804 0.554 -1.056
ENSG00000163960 E013 1.649575 8.369265e-03 2.035956e-02 1.457399e-01 3 196400129 196400732 604 - 0.581 0.231 -1.998
ENSG00000163960 E014 4.182272 3.271897e-03 1.505872e-02 1.208518e-01 3 196402952 196403019 68 - 0.853 0.554 -1.249
ENSG00000163960 E015 4.996792 7.707573e-02 2.910086e-02 1.805679e-01 3 196407246 196407393 148 - 0.938 0.581 -1.445
ENSG00000163960 E016 0.000000       3 196414645 196414684 40 -      
ENSG00000163960 E017 0.000000       3 196416157 196416235 79 -      
ENSG00000163960 E018 0.000000       3 196432327 196432430 104 -      

Help

Please Click HERE to learn more details about the results from DEXseq.