ENSG00000164168

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000296582 ENSG00000164168 No_inf pgwt_inf TMEM184C protein_coding protein_coding 84.88517 105.5063 59.76225 1.095273 0.7063461 -0.8199181 72.202312 74.81104 57.593575 1.722706 0.7428994 -0.3772856 0.87195833 0.709425 0.963775 0.254350 4.279489e-03 1.62097e-06 FALSE TRUE
ENST00000505999 ENSG00000164168 No_inf pgwt_inf TMEM184C protein_coding nonsense_mediated_decay 84.88517 105.5063 59.76225 1.095273 0.7063461 -0.8199181 5.090901 15.27270 0.000000 1.740199 0.0000000 -10.5776840 0.04815000 0.144450 0.000000 -0.144450 1.620970e-06 1.62097e-06 FALSE TRUE
ENST00000506826 ENSG00000164168 No_inf pgwt_inf TMEM184C protein_coding retained_intron 84.88517 105.5063 59.76225 1.095273 0.7063461 -0.8199181 4.896364 10.78887 1.410843 0.710114 0.2608927 -2.9260617 0.05135833 0.102400 0.023725 -0.078675 2.416545e-01 1.62097e-06 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000164168 E001 0.4909329 1.600623e-02 6.168183e-01   4 147617379 147617385 7 + 0.212 0.140 -0.726
ENSG00000164168 E002 0.9979802 1.554859e-02 9.948712e-01 1.000000e+00 4 147617386 147617396 11 + 0.289 0.290 0.011
ENSG00000164168 E003 19.0075628 8.574747e-03 5.209095e-03 5.976442e-02 4 147617397 147617507 111 + 1.408 1.195 -0.744
ENSG00000164168 E004 211.7554655 8.057456e-05 1.409449e-15 3.157047e-13 4 147617508 147618079 572 + 2.405 2.243 -0.541
ENSG00000164168 E005 76.7864842 2.074838e-04 2.023866e-02 1.452074e-01 4 147623834 147623964 131 + 1.920 1.840 -0.270
ENSG00000164168 E006 39.4885251 3.506630e-04 1.561859e-01 4.575008e-01 4 147624062 147624098 37 + 1.629 1.561 -0.231
ENSG00000164168 E007 111.3208854 1.543470e-04 2.723446e-02 1.742387e-01 4 147624804 147625009 206 + 2.069 2.006 -0.212
ENSG00000164168 E008 58.2731786 1.435004e-03 3.868350e-02 2.144926e-01 4 147628361 147628435 75 + 1.806 1.719 -0.293
ENSG00000164168 E009 36.3281536 1.453213e-03 1.425907e-02 1.168324e-01 4 147629599 147629611 13 + 1.629 1.503 -0.430
ENSG00000164168 E010 62.9806895 2.271609e-04 2.859512e-04 6.850182e-03 4 147629612 147629692 81 + 1.869 1.732 -0.465
ENSG00000164168 E011 80.7180458 2.860715e-04 1.511641e-01 4.498654e-01 4 147631393 147631505 113 + 1.922 1.873 -0.163
ENSG00000164168 E012 9.3112069 1.497832e-03 4.341798e-03 5.277643e-02 4 147632547 147632902 356 + 0.781 1.074 1.107
ENSG00000164168 E013 58.4571741 2.336639e-04 5.947625e-01 8.350144e-01 4 147632903 147632954 52 + 1.766 1.745 -0.069
ENSG00000164168 E014 76.1528732 1.871770e-04 2.175496e-01 5.406644e-01 4 147632955 147633002 48 + 1.893 1.850 -0.143
ENSG00000164168 E015 91.1760148 1.696584e-04 6.987850e-01 8.859944e-01 4 147633765 147633843 79 + 1.950 1.939 -0.038
ENSG00000164168 E016 109.4898623 1.749447e-03 1.786259e-01 4.907612e-01 4 147633844 147633936 93 + 2.050 2.006 -0.148
ENSG00000164168 E017 1586.0829834 5.345046e-05 8.646872e-28 4.781540e-25 4 147634169 147637649 3481 + 3.139 3.198 0.197
ENSG00000164168 E018 0.5076218 5.058969e-01 8.806929e-01   4 147671867 147672044 178 + 0.119 0.196 0.858

Help

Please Click HERE to learn more details about the results from DEXseq.