ENSG00000164465

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000338728 ENSG00000164465 No_inf pgwt_inf DCBLD1 protein_coding protein_coding 16.42034 12.75674 18.95572 1.766256 1.450002 0.5710043 5.7819875 1.1359913 8.3317195 0.6801376 1.1249211 2.8637487 0.34756667 0.10745 0.454925 0.347475 6.147444e-01 7.098961e-06 FALSE TRUE
ENST00000424717 ENSG00000164465 No_inf pgwt_inf DCBLD1 protein_coding nonsense_mediated_decay 16.42034 12.75674 18.95572 1.766256 1.450002 0.5710043 0.9175046 0.8697397 0.0000000 0.8697397 0.0000000 -6.4590047 0.05977500 0.07385 0.000000 -0.073850 9.928472e-01 7.098961e-06 FALSE TRUE
ENST00000478345 ENSG00000164465 No_inf pgwt_inf DCBLD1 protein_coding protein_coding_CDS_not_defined 16.42034 12.75674 18.95572 1.766256 1.450002 0.5710043 1.5092870 0.0000000 3.6400675 0.0000000 1.4372968 8.5117793 0.07654167 0.00000 0.186075 0.186075 3.085351e-01 7.098961e-06 FALSE TRUE
ENST00000487076 ENSG00000164465 No_inf pgwt_inf DCBLD1 protein_coding protein_coding_CDS_not_defined 16.42034 12.75674 18.95572 1.766256 1.450002 0.5710043 2.6002200 3.1958130 2.7243459 1.6560840 0.5419318 -0.2294945 0.15478333 0.22160 0.142300 -0.079300 1.000000e+00 7.098961e-06   FALSE
ENST00000528162 ENSG00000164465 No_inf pgwt_inf DCBLD1 protein_coding protein_coding_CDS_not_defined 16.42034 12.75674 18.95572 1.766256 1.450002 0.5710043 0.8210084 0.8626340 0.1809056 0.4982659 0.1809056 -2.1925173 0.05217500 0.06385 0.009925 -0.053925 9.928472e-01 7.098961e-06 FALSE FALSE
ENST00000534777 ENSG00000164465 No_inf pgwt_inf DCBLD1 protein_coding protein_coding_CDS_not_defined 16.42034 12.75674 18.95572 1.766256 1.450002 0.5710043 0.9850300 0.6123171 2.3427728 0.6123171 1.4254897 1.9186401 0.05213333 0.03405 0.122350 0.088300 9.928472e-01 7.098961e-06 FALSE TRUE
MSTRG.25219.7 ENSG00000164465 No_inf pgwt_inf DCBLD1 protein_coding   16.42034 12.75674 18.95572 1.766256 1.450002 0.5710043 2.5792209 5.1237036 0.0000000 0.5949462 0.0000000 -9.0038562 0.18414167 0.42420 0.000000 -0.424200 7.098961e-06 7.098961e-06 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000164465 E001 0.0000000       6 117453817 117453833 17 +      
ENSG00000164465 E002 0.0000000       6 117453834 117453897 64 +      
ENSG00000164465 E003 0.0000000       6 117464056 117464165 110 +      
ENSG00000164465 E004 0.0000000       6 117480346 117480470 125 +      
ENSG00000164465 E005 0.0000000       6 117480862 117480999 138 +      
ENSG00000164465 E006 0.2622978 0.2431238027 0.169339881   6 117482640 117482656 17 + 0.000 0.206 11.040
ENSG00000164465 E007 0.5073361 0.0288687922 0.160115368   6 117482657 117482673 17 + 0.078 0.281 2.200
ENSG00000164465 E008 4.1660143 0.0034817991 0.173635984 0.4831555 6 117482674 117482893 220 + 0.774 0.605 -0.707
ENSG00000164465 E009 0.2449549 0.0161944993 0.743180454   6 117484950 117484968 19 + 0.078 0.115 0.615
ENSG00000164465 E010 0.2453209 0.0161626104 0.743622778   6 117484969 117485040 72 + 0.078 0.115 0.615
ENSG00000164465 E011 0.0000000       6 117485041 117485042 2 +      
ENSG00000164465 E012 0.0000000       6 117494756 117494866 111 +      
ENSG00000164465 E013 0.0000000       6 117503559 117503766 208 +      
ENSG00000164465 E014 2.2712313 0.0078273596 0.469489289 0.7606970 6 117503767 117503783 17 + 0.553 0.450 -0.501
ENSG00000164465 E015 9.9884701 0.0194732110 0.553600764 0.8129585 6 117503784 117503979 196 + 1.060 1.004 -0.207
ENSG00000164465 E016 0.0000000       6 117508015 117508115 101 +      
ENSG00000164465 E017 9.2383942 0.0063212416 0.305567884 0.6325015 6 117519816 117519950 135 + 1.045 0.948 -0.357
ENSG00000164465 E018 4.6907682 0.0041074081 0.637347468 0.8558170 6 117521525 117521576 52 + 0.774 0.719 -0.222
ENSG00000164465 E019 5.0336903 0.0029537760 0.401167599 0.7123361 6 117525362 117525434 73 + 0.816 0.719 -0.385
ENSG00000164465 E020 9.7889209 0.0013511306 0.082819965 0.3288884 6 117532260 117532393 134 + 1.089 0.933 -0.574
ENSG00000164465 E021 6.6753389 0.0024609211 0.741643671 0.9067665 6 117537185 117537225 41 + 0.865 0.901 0.138
ENSG00000164465 E022 10.4662522 0.0035471186 0.394274628 0.7073492 6 117538620 117538774 155 + 1.021 1.097 0.278
ENSG00000164465 E023 7.4729717 0.0082233774 0.145939718 0.4417720 6 117538775 117538835 61 + 0.853 1.004 0.567
ENSG00000164465 E024 0.5872522 0.0152157435 0.361606246   6 117538836 117539254 419 + 0.253 0.115 -1.385
ENSG00000164465 E025 6.8259224 0.0022015336 0.005583228 0.0625430 6 117539255 117539308 54 + 0.744 1.029 1.091
ENSG00000164465 E026 7.0570106 0.0020302104 0.011930331 0.1041838 6 117539309 117539379 71 + 0.774 1.029 0.971
ENSG00000164465 E027 2.0926252 0.0075231720 0.273071082 0.6013296 6 117539380 117540667 1288 + 0.412 0.571 0.785
ENSG00000164465 E028 11.5832440 0.0015680975 0.263815153 0.5919727 6 117540668 117540815 148 + 1.053 1.147 0.340
ENSG00000164465 E029 8.3958340 0.0092495567 0.537509975 0.8034661 6 117540918 117541025 108 + 0.940 1.004 0.236
ENSG00000164465 E030 6.0525823 0.0025520667 0.957180209 0.9894582 6 117543124 117543211 88 + 0.841 0.849 0.030
ENSG00000164465 E031 2.9428989 0.1044483904 0.463770110 0.7567608 6 117544270 117544527 258 + 0.528 0.666 0.615
ENSG00000164465 E032 3.3997245 0.0043694947 0.730839008 0.9018438 6 117544528 117544531 4 + 0.620 0.666 0.200
ENSG00000164465 E033 5.3619928 0.0032985169 0.435888217 0.7378641 6 117544532 117544577 46 + 0.760 0.849 0.352
ENSG00000164465 E034 8.7303299 0.0564900216 0.827992738 0.9420438 6 117545478 117545597 120 + 0.969 1.004 0.128
ENSG00000164465 E035 116.7083216 0.0001630273 0.012479512 0.1073898 6 117547907 117549797 1891 + 2.087 2.037 -0.169
ENSG00000164465 E036 1.2464641 0.0972686226 0.244225856 0.5704310 6 117569620 117569858 239 + 0.253 0.450 1.199

Help

Please Click HERE to learn more details about the results from DEXseq.