ENSG00000165025

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000375746 ENSG00000165025 No_inf pgwt_inf SYK protein_coding protein_coding 36.26143 47.71874 26.59789 2.218185 0.3001981 -0.8430045 2.517870 0.000000 3.206800 0.000000 3.206800 8.32948222 0.0813750 0.00000 0.117075 0.117075 9.928472e-01 1.053632e-07 FALSE TRUE
ENST00000375751 ENSG00000165025 No_inf pgwt_inf SYK protein_coding protein_coding 36.26143 47.71874 26.59789 2.218185 0.3001981 -0.8430045 5.626218 8.185273 2.349223 2.113940 1.443526 -1.79647989 0.1472417 0.16910 0.089825 -0.079275 9.925282e-01 1.053632e-07 FALSE TRUE
ENST00000375754 ENSG00000165025 No_inf pgwt_inf SYK protein_coding protein_coding 36.26143 47.71874 26.59789 2.218185 0.3001981 -0.8430045 20.411139 20.897447 20.747156 2.012067 2.792261 -0.01040811 0.5969667 0.44085 0.782350 0.341500 8.909682e-01 1.053632e-07 FALSE TRUE
MSTRG.28931.7 ENSG00000165025 No_inf pgwt_inf SYK protein_coding   36.26143 47.71874 26.59789 2.218185 0.3001981 -0.8430045 6.087092 17.157182 0.000000 1.567103 0.000000 -10.74543751 0.1300083 0.35740 0.000000 -0.357400 1.053632e-07 1.053632e-07 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000165025 E001 1.5406589 8.623032e-03 9.016047e-02 3.446575e-01 9 90801787 90801818 32 + 0.206 0.473 1.699
ENSG00000165025 E002 7.2637039 1.652606e-02 2.585593e-01 5.862606e-01 9 90801819 90801893 75 + 0.978 0.852 -0.476
ENSG00000165025 E003 0.3765532 1.674610e-02 8.906005e-01   9 90801927 90801961 35 + 0.115 0.144 0.377
ENSG00000165025 E004 0.2631768 1.613325e-02 4.281693e-01   9 90801962 90802005 44 + 0.000 0.144 9.791
ENSG00000165025 E005 0.6225922 2.421909e-01 1.000000e+00   9 90802006 90802039 34 + 0.206 0.202 -0.037
ENSG00000165025 E006 0.7011146 2.809057e-02 3.054777e-02 1.866299e-01 9 90827488 90827579 92 + 0.401 0.078 -2.944
ENSG00000165025 E007 44.8739816 3.386693e-04 4.471340e-03 5.375910e-02 9 90843858 90844315 458 + 1.721 1.594 -0.432
ENSG00000165025 E008 22.9567756 6.448552e-04 4.442936e-03 5.354318e-02 9 90845434 90845594 161 + 1.466 1.291 -0.607
ENSG00000165025 E009 22.6290401 8.120541e-03 7.481909e-01 9.096964e-01 9 90862206 90862344 139 + 1.371 1.349 -0.077
ENSG00000165025 E010 17.0839448 7.813475e-04 2.390556e-02 1.609013e-01 9 90864589 90864667 79 + 1.336 1.176 -0.560
ENSG00000165025 E011 17.8835298 9.162708e-04 3.747837e-03 4.754066e-02 9 90865048 90865097 50 + 1.376 1.176 -0.702
ENSG00000165025 E012 23.7000600 1.960024e-02 3.327707e-02 1.958260e-01 9 90867131 90867199 69 + 1.479 1.304 -0.607
ENSG00000165025 E013 28.7811692 4.803444e-04 1.813400e-04 4.746852e-03 9 90874204 90874291 88 + 1.577 1.371 -0.708
ENSG00000165025 E014 50.9792024 3.091870e-04 4.700705e-02 2.391047e-01 9 90874672 90874849 178 + 1.750 1.666 -0.285
ENSG00000165025 E015 69.1170345 2.562373e-04 1.205667e-02 1.050280e-01 9 90877571 90877780 210 + 1.884 1.794 -0.306
ENSG00000165025 E016 53.6833957 3.054563e-04 1.862878e-01 5.002283e-01 9 90878764 90878953 190 + 1.755 1.700 -0.186
ENSG00000165025 E017 1.4446369 2.267996e-02 2.468357e-03 3.538623e-02 9 90885926 90885974 49 + 0.000 0.501 12.097
ENSG00000165025 E018 45.0029609 5.214352e-03 3.106468e-01 6.369393e-01 9 90887749 90887889 141 + 1.679 1.626 -0.182
ENSG00000165025 E019 51.0597963 1.892388e-03 4.461976e-02 2.320384e-01 9 90888515 90888627 113 + 1.755 1.664 -0.307
ENSG00000165025 E020 612.7234684 5.929523e-05 4.970012e-22 1.968941e-19 9 90895528 90898549 3022 + 2.716 2.799 0.276

Help

Please Click HERE to learn more details about the results from DEXseq.