ENSG00000166986

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000262027 ENSG00000166986 No_inf pgwt_inf MARS1 protein_coding protein_coding 99.79287 103.6259 95.60777 6.772524 3.716691 -0.1161732 27.486987 19.045539 33.3647042 1.5120816 3.1912968 0.8085446 0.27873333 0.183750 0.354350 0.170600 8.714742e-01 2.541902e-05 FALSE TRUE
ENST00000545888 ENSG00000166986 No_inf pgwt_inf MARS1 protein_coding nonsense_mediated_decay 99.79287 103.6259 95.60777 6.772524 3.716691 -0.1161732 6.442674 4.189131 7.3489257 1.8673506 1.0397487 0.8094042 0.06577500 0.039925 0.076625 0.036700 9.928472e-01 2.541902e-05 TRUE TRUE
ENST00000548202 ENSG00000166986 No_inf pgwt_inf MARS1 protein_coding retained_intron 99.79287 103.6259 95.60777 6.772524 3.716691 -0.1161732 12.292706 14.114383 11.1955456 1.9413262 1.3252175 -0.3339750 0.12364167 0.134550 0.117525 -0.017025 9.954679e-01 2.541902e-05 FALSE FALSE
ENST00000551805 ENSG00000166986 No_inf pgwt_inf MARS1 protein_coding retained_intron 99.79287 103.6259 95.60777 6.772524 3.716691 -0.1161732 5.619090 8.872099 4.4352784 2.9776200 1.5519919 -0.9986268 0.05519167 0.082375 0.045925 -0.036450 9.928472e-01 2.541902e-05 FALSE FALSE
ENST00000552914 ENSG00000166986 No_inf pgwt_inf MARS1 protein_coding protein_coding 99.79287 103.6259 95.60777 6.772524 3.716691 -0.1161732 11.951839 6.175619 11.7029046 3.6040909 2.2457891 0.9211090 0.11965000 0.056775 0.121325 0.064550 9.729762e-01 2.541902e-05 FALSE TRUE
MSTRG.6728.2 ENSG00000166986 No_inf pgwt_inf MARS1 protein_coding   99.79287 103.6259 95.60777 6.772524 3.716691 -0.1161732 2.819131 7.169420 0.8014389 0.7775423 0.4687214 -3.1453129 0.02820833 0.071500 0.008025 -0.063475 2.904896e-01 2.541902e-05 FALSE TRUE
MSTRG.6728.3 ENSG00000166986 No_inf pgwt_inf MARS1 protein_coding   99.79287 103.6259 95.60777 6.772524 3.716691 -0.1161732 3.312866 9.166134 0.0000000 1.8512281 0.0000000 -9.8417426 0.03261667 0.091600 0.000000 -0.091600 2.541902e-05 2.541902e-05 TRUE TRUE
MSTRG.6728.4 ENSG00000166986 No_inf pgwt_inf MARS1 protein_coding   99.79287 103.6259 95.60777 6.772524 3.716691 -0.1161732 2.286153 0.000000 5.4822672 0.0000000 2.4462271 9.1012580 0.02429167 0.000000 0.056450 0.056450 2.297545e-01 2.541902e-05 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000166986 E001 0.0000000       12 57475445 57475642 198 +      
ENSG00000166986 E002 0.0000000       12 57476882 57476937 56 +      
ENSG00000166986 E003 0.0000000       12 57477240 57477307 68 +      
ENSG00000166986 E004 0.0000000       12 57477308 57477372 65 +      
ENSG00000166986 E005 0.0000000       12 57477373 57477374 2 +      
ENSG00000166986 E006 0.0000000       12 57477375 57477446 72 +      
ENSG00000166986 E007 5.2788774 0.0292292313 5.646391e-05 1.846853e-03 12 57487294 57487305 12 + 0.403 0.966 2.432
ENSG00000166986 E008 9.1170725 0.0050705225 1.097609e-07 7.656727e-06 12 57487306 57487385 80 + 0.608 1.173 2.186
ENSG00000166986 E009 17.0032666 0.0098146715 3.859158e-13 6.524435e-11 12 57487386 57487635 250 + 0.766 1.441 2.460
ENSG00000166986 E010 15.5788391 0.0025311675 6.577850e-14 1.204110e-11 12 57487636 57487825 190 + 0.747 1.402 2.405
ENSG00000166986 E011 14.9209176 0.0031333924 9.673459e-13 1.526997e-10 12 57487937 57488023 87 + 0.747 1.382 2.333
ENSG00000166986 E012 8.3099592 0.0164186439 2.599619e-05 9.569321e-04 12 57488024 57488029 6 + 0.634 1.122 1.888
ENSG00000166986 E013 11.4435838 0.0186206784 4.050559e-08 3.129956e-06 12 57488030 57488055 26 + 0.659 1.271 2.310
ENSG00000166986 E014 8.3293308 0.0023169075 9.103587e-07 5.230228e-05 12 57488056 57488061 6 + 0.608 1.130 2.031
ENSG00000166986 E015 7.6713908 0.0018215005 7.767071e-06 3.407626e-04 12 57488062 57488065 4 + 0.608 1.090 1.888
ENSG00000166986 E016 7.7862106 0.0018567049 1.860148e-05 7.239575e-04 12 57488066 57488067 2 + 0.634 1.090 1.773
ENSG00000166986 E017 11.0419860 0.0013576469 8.764185e-03 8.517661e-02 12 57488068 57488084 17 + 0.936 1.166 0.839
ENSG00000166986 E018 10.6601249 0.0013754613 3.540454e-01 6.740939e-01 12 57488085 57488090 6 + 1.018 1.098 0.293
ENSG00000166986 E019 13.9150873 0.0143470503 9.236496e-01 9.783574e-01 12 57488091 57488102 12 + 1.169 1.173 0.016
ENSG00000166986 E020 29.6910766 0.0077956266 8.062987e-01 9.336502e-01 12 57488103 57488199 97 + 1.477 1.490 0.044
ENSG00000166986 E021 6.9026372 0.0316510442 3.361684e-04 7.735516e-03 12 57488212 57488661 450 + 0.580 1.046 1.855
ENSG00000166986 E022 2.0669297 0.0165969924 3.181589e-03 4.235151e-02 12 57488686 57489018 333 + 0.179 0.633 2.696
ENSG00000166986 E023 31.3059355 0.0034477975 3.591806e-02 2.055126e-01 12 57489019 57489109 91 + 1.570 1.448 -0.416
ENSG00000166986 E024 0.5077021 0.0153400601 3.581700e-01   12 57489110 57489266 157 + 0.098 0.232 1.473
ENSG00000166986 E025 30.1637009 0.0028808745 1.436409e-02 1.173849e-01 12 57489267 57489345 79 + 1.564 1.422 -0.486
ENSG00000166986 E026 0.8846751 0.0131966976 2.980768e-01 6.256408e-01 12 57489346 57489423 78 + 0.179 0.338 1.210
ENSG00000166986 E027 20.9923114 0.0006662551 1.178694e-01 3.973405e-01 12 57489424 57489454 31 + 1.392 1.292 -0.347
ENSG00000166986 E028 32.8282224 0.0094653034 3.979901e-01 7.101993e-01 12 57489455 57489529 75 + 1.558 1.500 -0.198
ENSG00000166986 E029 22.4969883 0.0065131068 2.716692e-01 5.997850e-01 12 57489530 57489558 29 + 1.410 1.332 -0.269
ENSG00000166986 E030 1.3922402 0.0447573950 1.841780e-01 4.975457e-01 12 57489559 57489783 225 + 0.246 0.460 1.303
ENSG00000166986 E031 36.0674516 0.0005040843 4.382220e-01 7.396023e-01 12 57489896 57489971 76 + 1.587 1.549 -0.132
ENSG00000166986 E032 0.2449549 0.0164922384 9.514450e-01   12 57489972 57490033 62 + 0.098 0.092 -0.112
ENSG00000166986 E033 34.9085382 0.0014141489 2.529491e-01 5.800680e-01 12 57490207 57490277 71 + 1.584 1.525 -0.203
ENSG00000166986 E034 29.3785353 0.0045624575 6.062271e-02 2.771458e-01 12 57490278 57490379 102 + 1.539 1.426 -0.388
ENSG00000166986 E035 45.5837339 0.0003265295 2.445591e-01 5.709650e-01 12 57490538 57490644 107 + 1.693 1.642 -0.174
ENSG00000166986 E036 49.2102812 0.0004913875 9.392058e-01 9.839299e-01 12 57498157 57498273 117 + 1.700 1.697 -0.011
ENSG00000166986 E037 73.6684993 0.0002168196 8.582692e-01 9.543196e-01 12 57498420 57498623 204 + 1.874 1.868 -0.020
ENSG00000166986 E038 0.7356052 0.0136732219 9.245875e-01 9.786584e-01 12 57500114 57500320 207 + 0.246 0.232 -0.112
ENSG00000166986 E039 27.1091493 0.0036581184 5.440782e-01 8.077085e-01 12 57500321 57500357 37 + 1.466 1.430 -0.125
ENSG00000166986 E040 50.6432105 0.0002770009 1.576396e-02 1.242533e-01 12 57500358 57500490 133 + 1.763 1.663 -0.342
ENSG00000166986 E041 33.0639671 0.0004443635 2.629654e-01 5.910403e-01 12 57500491 57500522 32 + 1.561 1.503 -0.197
ENSG00000166986 E042 0.2631768 0.0161351289 2.703821e-01   12 57503986 57504224 239 + 0.000 0.168 9.918
ENSG00000166986 E043 44.5089679 0.0003327071 3.168624e-01 6.422909e-01 12 57504225 57504299 75 + 1.680 1.635 -0.152
ENSG00000166986 E044 0.7697750 0.0298526159 1.170122e-01 3.957259e-01 12 57511586 57511697 112 + 0.098 0.338 2.210
ENSG00000166986 E045 45.0632302 0.0003576010 5.559152e-01 8.141053e-01 12 57511698 57511768 71 + 1.675 1.649 -0.088
ENSG00000166986 E046 31.6746038 0.0004347975 6.176680e-01 8.463560e-01 12 57511769 57511796 28 + 1.526 1.500 -0.090
ENSG00000166986 E047 44.0382907 0.0006664200 4.360595e-01 7.379498e-01 12 57511797 57511868 72 + 1.670 1.635 -0.120
ENSG00000166986 E048 50.3026005 0.0005587931 8.865643e-01 9.645480e-01 12 57512008 57512103 96 + 1.711 1.705 -0.020
ENSG00000166986 E049 3.8981961 0.0077745773 8.320234e-02 3.296671e-01 12 57512104 57512235 132 + 0.550 0.774 0.959
ENSG00000166986 E050 36.7805342 0.0011257549 3.770928e-01 6.945751e-01 12 57512236 57512302 67 + 1.599 1.555 -0.150
ENSG00000166986 E051 28.1568370 0.0093688268 3.497364e-01 6.702331e-01 12 57512303 57512353 51 + 1.495 1.434 -0.212
ENSG00000166986 E052 3.8635282 0.0756163933 4.187116e-01 7.250456e-01 12 57512354 57512464 111 + 0.608 0.738 0.551
ENSG00000166986 E053 8.1682743 0.0019822307 5.083471e-01 7.855806e-01 12 57512491 57512687 197 + 0.923 0.987 0.240
ENSG00000166986 E054 5.0117197 0.0028358400 9.949444e-02 3.637076e-01 12 57512688 57512750 63 + 0.659 0.853 0.781
ENSG00000166986 E055 79.4464662 0.0002291036 4.245963e-01 7.293593e-01 12 57512751 57512929 179 + 1.917 1.891 -0.090
ENSG00000166986 E056 36.3618668 0.0124170459 1.214539e-01 4.031452e-01 12 57512930 57512964 35 + 1.623 1.522 -0.345
ENSG00000166986 E057 69.3632035 0.0071616017 2.162300e-02 1.511958e-01 12 57514720 57514821 102 + 1.904 1.791 -0.381
ENSG00000166986 E058 37.2756378 0.0117812379 5.968088e-02 2.746138e-01 12 57514822 57514851 30 + 1.644 1.522 -0.415
ENSG00000166986 E059 54.5273453 0.0072545240 3.371440e-01 6.599487e-01 12 57514954 57515014 61 + 1.769 1.719 -0.170
ENSG00000166986 E060 52.7344167 0.0008836669 7.883379e-01 9.266369e-01 12 57515015 57515058 44 + 1.734 1.723 -0.038
ENSG00000166986 E061 51.4698514 0.0054649495 7.121166e-01 8.929522e-01 12 57515150 57515180 31 + 1.728 1.709 -0.064
ENSG00000166986 E062 37.8641636 0.0045308527 8.483575e-01 9.502245e-01 12 57515181 57515182 2 + 1.593 1.582 -0.037
ENSG00000166986 E063 47.4400886 0.0016345530 6.959426e-01 8.843548e-01 12 57515183 57515216 34 + 1.673 1.691 0.061
ENSG00000166986 E064 81.0541340 0.0002031040 2.001113e-01 5.185039e-01 12 57515217 57515336 120 + 1.935 1.892 -0.142
ENSG00000166986 E065 2.0440514 0.0092352338 1.745441e-01 4.844887e-01 12 57515337 57515493 157 + 0.580 0.383 -0.986
ENSG00000166986 E066 53.7212708 0.0002816501 8.501725e-02 3.337760e-01 12 57515920 57515991 72 + 1.773 1.703 -0.237
ENSG00000166986 E067 21.2934764 0.0007450703 8.709869e-04 1.615556e-02 12 57515992 57516138 147 + 1.211 1.430 0.763
ENSG00000166986 E068 10.1709146 0.0014164349 7.961458e-03 7.989451e-02 12 57516139 57516158 20 + 0.896 1.137 0.888
ENSG00000166986 E069 12.4749138 0.0011538408 4.526210e-02 2.338248e-01 12 57516159 57516244 86 + 1.028 1.193 0.594
ENSG00000166986 E070 64.8583853 0.0002223664 2.279027e-01 5.529986e-01 12 57516245 57516337 93 + 1.840 1.796 -0.150
ENSG00000166986 E071 2.9777347 0.0071381139 5.388916e-01 8.042620e-01 12 57516338 57516434 97 + 0.550 0.633 0.374
ENSG00000166986 E072 41.3272679 0.0066958748 8.971810e-01 9.692257e-01 12 57516435 57516494 60 + 1.628 1.621 -0.026
ENSG00000166986 E073 20.9313464 0.0010077423 3.043248e-01 6.311116e-01 12 57516495 57516564 70 + 1.374 1.308 -0.230
ENSG00000166986 E074 3.7800773 0.0037615915 4.564398e-01 7.522919e-01 12 57516565 57516655 91 + 0.726 0.633 -0.392
ENSG00000166986 E075 0.0000000       12 57517283 57517569 287 +      

Help

Please Click HERE to learn more details about the results from DEXseq.