ENSG00000167004

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000300289 ENSG00000167004 No_inf pgwt_inf PDIA3 protein_coding protein_coding 769.7011 603.3972 901.3119 12.31488 14.70272 0.5789105 135.19688 122.62991 141.32005 1.984015 3.876509 0.2046398 0.17887500 0.203375 0.157000 -0.046375 9.928472e-01 1.38149e-09 FALSE  
ENST00000455250 ENSG00000167004 No_inf pgwt_inf PDIA3 protein_coding nonsense_mediated_decay 769.7011 603.3972 901.3119 12.31488 14.70272 0.5789105 30.57956 0.00000 59.44229 0.000000 8.341692 12.5375167 0.03534167 0.000000 0.065900 0.065900 1.381490e-09 1.38149e-09 FALSE  
ENST00000686374 ENSG00000167004 No_inf pgwt_inf PDIA3 protein_coding retained_intron 769.7011 603.3972 901.3119 12.31488 14.70272 0.5789105 435.90425 367.08302 502.45609 10.135417 17.662846 0.4528806 0.57000833 0.608100 0.557200 -0.050900 9.928472e-01 1.38149e-09 FALSE  
ENST00000686929 ENSG00000167004 No_inf pgwt_inf PDIA3 protein_coding protein_coding 769.7011 603.3972 901.3119 12.31488 14.70272 0.5789105 118.72929 82.86885 135.50595 4.443616 4.798163 0.7093868 0.15294167 0.137100 0.150425 0.013325 1.000000e+00 1.38149e-09 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000167004 E001 3.9104520 4.169806e-03 0.580084278 0.82660530 15 43746394 43746404 11 + 0.657 0.726 0.290
ENSG00000167004 E002 5.7234929 2.366336e-03 0.708170396 0.89120312 15 43746405 43746407 3 + 0.807 0.848 0.163
ENSG00000167004 E003 7.2922285 1.888329e-03 0.829768604 0.94263689 15 43746408 43746409 2 + 0.907 0.929 0.084
ENSG00000167004 E004 11.9639880 1.269108e-03 0.611410752 0.84327910 15 43746410 43746422 13 + 1.130 1.088 -0.151
ENSG00000167004 E005 11.9639880 1.269108e-03 0.611410752 0.84327910 15 43746423 43746424 2 + 1.130 1.088 -0.151
ENSG00000167004 E006 15.4959329 2.144759e-03 0.769326895 0.91899729 15 43746425 43746427 3 + 1.225 1.204 -0.077
ENSG00000167004 E007 27.5440222 1.797000e-03 0.392547012 0.70587676 15 43746428 43746436 9 + 1.476 1.426 -0.173
ENSG00000167004 E008 27.8854401 3.236816e-03 0.328399420 0.65254813 15 43746437 43746437 1 + 1.485 1.426 -0.203
ENSG00000167004 E009 29.1899847 7.870363e-03 0.299173230 0.62660420 15 43746438 43746438 1 + 1.508 1.440 -0.235
ENSG00000167004 E010 31.4281512 3.529272e-03 0.121489857 0.40322206 15 43746439 43746441 3 + 1.548 1.457 -0.311
ENSG00000167004 E011 40.0808882 1.315200e-03 0.230791360 0.55655394 15 43746442 43746447 6 + 1.638 1.579 -0.202
ENSG00000167004 E012 44.1501273 4.313983e-03 0.189080818 0.50331165 15 43746448 43746448 1 + 1.683 1.613 -0.237
ENSG00000167004 E013 52.9271972 9.650161e-04 0.075574098 0.31243101 15 43746449 43746451 3 + 1.763 1.686 -0.261
ENSG00000167004 E014 52.9102771 7.647310e-04 0.058833956 0.27236936 15 43746452 43746452 1 + 1.765 1.684 -0.275
ENSG00000167004 E015 56.9759771 1.534657e-03 0.007416372 0.07632910 15 43746453 43746483 31 + 1.810 1.694 -0.394
ENSG00000167004 E016 50.1577052 3.057913e-03 0.004541394 0.05437178 15 43746484 43746570 87 + 1.765 1.625 -0.473
ENSG00000167004 E017 0.0000000       15 43746571 43746706 136 +      
ENSG00000167004 E018 0.3768926 1.395902e-01 0.433828526   15 43750201 43750446 246 + 0.082 0.198 1.470
ENSG00000167004 E019 0.5889768 1.537596e-02 0.311286799   15 43751189 43751505 317 + 0.263 0.110 -1.529
ENSG00000167004 E020 0.1311489 1.218767e-02 0.385902913   15 43751506 43751583 78 + 0.000 0.110 10.746
ENSG00000167004 E021 0.2620121 1.600796e-02 0.149849704   15 43751584 43751758 175 + 0.000 0.198 11.637
ENSG00000167004 E022 0.6563377 1.428184e-02 0.007708949 0.07821813 15 43752802 43752946 145 + 0.000 0.388 12.988
ENSG00000167004 E023 120.4643858 2.305818e-04 0.333209659 0.65662304 15 43753824 43753902 79 + 2.095 2.068 -0.090
ENSG00000167004 E024 0.2454580 1.606496e-02 0.800715495   15 43756628 43756648 21 + 0.082 0.110 0.471
ENSG00000167004 E025 305.9946410 5.015225e-04 0.066872176 0.29258850 15 43756649 43756766 118 + 2.501 2.466 -0.118
ENSG00000167004 E026 11.1622869 1.254105e-03 0.002896052 0.03981865 15 43756767 43759996 3230 + 0.950 1.204 0.923
ENSG00000167004 E027 275.1550664 6.893286e-05 0.061893238 0.28000375 15 43761424 43761531 108 + 2.454 2.420 -0.113
ENSG00000167004 E028 0.3429450 2.506425e-02 0.184307715   15 43761532 43762181 650 + 0.211 0.000 -12.301
ENSG00000167004 E029 215.7591248 1.008000e-04 0.842183069 0.94781864 15 43763077 43763151 75 + 2.336 2.332 -0.012
ENSG00000167004 E030 239.0326079 7.751911e-05 0.744322286 0.90820081 15 43763152 43763206 55 + 2.375 2.382 0.023
ENSG00000167004 E031 0.1145948 1.111270e-02 0.745332973   15 43765435 43765449 15 + 0.082 0.000 -11.070
ENSG00000167004 E032 447.2945865 9.334381e-05 0.411789765 0.72006319 15 43765450 43765566 117 + 2.655 2.643 -0.038
ENSG00000167004 E033 0.2450383 1.605600e-02 0.800732707   15 43765567 43765886 320 + 0.082 0.110 0.471
ENSG00000167004 E034 478.7782815 5.820831e-05 0.252133936 0.57910190 15 43765887 43766012 126 + 2.686 2.671 -0.051
ENSG00000167004 E035 517.2192361 5.647717e-05 0.041644048 0.22384730 15 43766728 43766910 183 + 2.725 2.698 -0.089
ENSG00000167004 E036 1.9794895 3.425393e-01 0.431668036 0.73437458 15 43766911 43767522 612 + 0.390 0.555 0.831
ENSG00000167004 E037 611.3512869 4.104423e-05 0.056370024 0.26551361 15 43768489 43768597 109 + 2.795 2.773 -0.075
ENSG00000167004 E038 0.2453240 1.604525e-02 0.800857445   15 43768598 43769496 899 + 0.082 0.110 0.471
ENSG00000167004 E039 0.0000000       15 43769497 43769517 21 +      
ENSG00000167004 E040 272.4868298 2.486056e-04 0.759512345 0.91465815 15 43769518 43769521 4 + 2.438 2.432 -0.018
ENSG00000167004 E041 528.6990672 5.030767e-05 0.228004083 0.55306487 15 43769522 43769646 125 + 2.715 2.731 0.054
ENSG00000167004 E042 0.7014201 1.462652e-02 0.192796421 0.50828322 15 43769647 43770249 603 + 0.310 0.110 -1.851
ENSG00000167004 E043 251.3858086 2.271130e-04 0.081802174 0.32712243 15 43770250 43770254 5 + 2.384 2.419 0.117
ENSG00000167004 E044 506.7712383 5.076094e-05 0.004434873 0.05345815 15 43770255 43770329 75 + 2.686 2.724 0.128
ENSG00000167004 E045 1.6831055 8.900675e-03 0.639219544 0.85698344 15 43770330 43770522 193 + 0.458 0.388 -0.377
ENSG00000167004 E046 406.2747669 4.922542e-05 0.007958347 0.07988096 15 43770523 43770571 49 + 2.589 2.630 0.134
ENSG00000167004 E047 243.3289983 7.593564e-05 0.069300126 0.29831872 15 43770572 43770580 9 + 2.369 2.405 0.120
ENSG00000167004 E048 1.3239342 1.007354e-02 0.709739199 0.89214849 15 43770581 43771085 505 + 0.390 0.333 -0.337
ENSG00000167004 E049 0.0000000       15 43771086 43771104 19 +      
ENSG00000167004 E050 1076.1503291 2.150025e-04 0.000640083 0.01274548 15 43771105 43773279 2175 + 3.014 3.049 0.116

Help

Please Click HERE to learn more details about the results from DEXseq.