ENSG00000167978

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000301740 ENSG00000167978 No_inf pgwt_inf SRRM2 protein_coding protein_coding 147.4744 197.3863 144.6618 5.652455 2.492887 -0.4483111 14.480589 19.042584 14.277804 2.120938 1.994658 -0.4152025 0.09857500 0.096275 0.098750 0.002475 1.000000e+00 7.655567e-09 FALSE TRUE
ENST00000572883 ENSG00000167978 No_inf pgwt_inf SRRM2 protein_coding nonsense_mediated_decay 147.4744 197.3863 144.6618 5.652455 2.492887 -0.4483111 10.870981 14.507609 11.094791 1.516854 0.749741 -0.3866217 0.07409167 0.073300 0.076925 0.003625 1.000000e+00 7.655567e-09 TRUE TRUE
ENST00000573311 ENSG00000167978 No_inf pgwt_inf SRRM2 protein_coding retained_intron 147.4744 197.3863 144.6618 5.652455 2.492887 -0.4483111 19.925055 28.995238 23.740232 1.638170 1.597426 -0.2883719 0.12726667 0.147525 0.163725 0.016200 1.000000e+00 7.655567e-09 FALSE FALSE
ENST00000574331 ENSG00000167978 No_inf pgwt_inf SRRM2 protein_coding retained_intron 147.4744 197.3863 144.6618 5.652455 2.492887 -0.4483111 23.261549 34.594762 21.759023 2.502202 2.757820 -0.6686939 0.15305833 0.175175 0.150850 -0.024325 9.932366e-01 7.655567e-09   FALSE
ENST00000574593 ENSG00000167978 No_inf pgwt_inf SRRM2 protein_coding protein_coding_CDS_not_defined 147.4744 197.3863 144.6618 5.652455 2.492887 -0.4483111 8.203236 14.827638 4.490196 2.167207 1.586583 -1.7212017 0.05213333 0.074425 0.030775 -0.043650 9.928472e-01 7.655567e-09 FALSE TRUE
MSTRG.10497.13 ENSG00000167978 No_inf pgwt_inf SRRM2 protein_coding   147.4744 197.3863 144.6618 5.652455 2.492887 -0.4483111 9.195685 0.000000 16.773376 0.000000 1.767826 10.7128172 0.07419167 0.000000 0.116150 0.116150 7.655567e-09 7.655567e-09 FALSE TRUE
MSTRG.10497.15 ENSG00000167978 No_inf pgwt_inf SRRM2 protein_coding   147.4744 197.3863 144.6618 5.652455 2.492887 -0.4483111 6.936906 14.700835 1.532934 1.845522 1.532934 -3.2531311 0.04459167 0.075375 0.010725 -0.064650 1.755650e-01 7.655567e-09 TRUE TRUE
MSTRG.10497.25 ENSG00000167978 No_inf pgwt_inf SRRM2 protein_coding   147.4744 197.3863 144.6618 5.652455 2.492887 -0.4483111 9.284974 12.747093 9.398380 1.876593 1.284576 -0.4392813 0.06250833 0.065275 0.064875 -0.000400 1.000000e+00 7.655567e-09 TRUE TRUE
MSTRG.10497.26 ENSG00000167978 No_inf pgwt_inf SRRM2 protein_coding   147.4744 197.3863 144.6618 5.652455 2.492887 -0.4483111 11.836614 3.952382 15.406600 1.389765 1.364158 1.9600447 0.09530833 0.020375 0.106450 0.086075 6.634272e-01 7.655567e-09 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000167978 E001 0.0000000       16 2752626 2752637 12 +      
ENSG00000167978 E002 0.2626639 1.613342e-02 3.075717e-01   16 2752638 2752648 11 + 0.000 0.160 10.143
ENSG00000167978 E003 1.1459037 2.951038e-02 1.554884e-01 4.565509e-01 16 2752649 2752661 13 + 0.187 0.409 1.544
ENSG00000167978 E004 1.8644388 1.787395e-02 6.684179e-01 8.714745e-01 16 2752662 2752674 13 + 0.417 0.479 0.322
ENSG00000167978 E005 5.3510084 2.963059e-03 4.228936e-01 7.282916e-01 16 2752675 2752715 41 + 0.745 0.833 0.350
ENSG00000167978 E006 19.0512331 1.055155e-03 7.078176e-01 8.911256e-01 16 2752716 2752846 131 + 1.284 1.306 0.076
ENSG00000167978 E007 1.4907016 2.268361e-02 7.842104e-01 9.251913e-01 16 2752847 2752854 8 + 0.369 0.409 0.222
ENSG00000167978 E008 0.7378316 5.557737e-02 8.387161e-01 9.463142e-01 16 2753443 2753645 203 + 0.256 0.223 -0.263
ENSG00000167978 E009 26.6232858 1.033302e-03 1.134753e-01 3.895214e-01 16 2756334 2756478 145 + 1.381 1.471 0.311
ENSG00000167978 E010 31.3587486 4.930394e-04 7.640265e-02 3.145336e-01 16 2756479 2756606 128 + 1.449 1.541 0.317
ENSG00000167978 E011 15.3437927 8.999398e-04 9.806449e-02 3.609609e-01 16 2757472 2757475 4 + 1.134 1.255 0.430
ENSG00000167978 E012 41.2403457 5.546532e-03 4.969587e-01 7.784235e-01 16 2757476 2757574 99 + 1.601 1.634 0.111
ENSG00000167978 E013 22.8889136 5.899257e-03 7.294617e-01 9.014168e-01 16 2757575 2757579 5 + 1.362 1.381 0.066
ENSG00000167978 E014 0.3600528 2.187687e-01 5.370224e-01   16 2757580 2757780 201 + 0.187 0.088 -1.264
ENSG00000167978 E015 63.7487053 2.958887e-03 3.965439e-01 7.089527e-01 16 2757781 2757945 165 + 1.829 1.788 -0.141
ENSG00000167978 E016 37.9362978 3.725271e-04 3.170557e-01 6.425355e-01 16 2758470 2758547 78 + 1.558 1.603 0.155
ENSG00000167978 E017 0.7867684 2.543418e-02 1.728937e-02 1.321465e-01 16 2758854 2758907 54 + 0.000 0.369 13.785
ENSG00000167978 E018 0.5078433 3.224237e-02 4.137758e-01   16 2758908 2758923 16 + 0.103 0.223 1.322
ENSG00000167978 E019 0.4727944 1.546367e-02 2.431962e-01   16 2758924 2758957 34 + 0.256 0.088 -1.848
ENSG00000167978 E020 0.5881879 1.442806e-02 1.210617e-01   16 2758958 2758984 27 + 0.317 0.088 -2.263
ENSG00000167978 E021 39.7035700 5.544676e-04 6.884514e-01 8.810231e-01 16 2758985 2759047 63 + 1.595 1.610 0.053
ENSG00000167978 E022 0.8840331 1.227412e-02 3.582256e-01 6.779668e-01 16 2759048 2759139 92 + 0.187 0.326 1.059
ENSG00000167978 E023 32.9982892 4.293248e-04 8.112015e-01 9.356533e-01 16 2759140 2759172 33 + 1.521 1.530 0.030
ENSG00000167978 E024 0.4738660 1.546450e-02 2.430884e-01   16 2759173 2759351 179 + 0.256 0.088 -1.848
ENSG00000167978 E025 36.3669972 3.663897e-03 7.286416e-01 9.009559e-01 16 2759352 2759402 51 + 1.580 1.557 -0.077
ENSG00000167978 E026 0.1308632 1.234229e-02 6.385062e-01   16 2759403 2759548 146 + 0.000 0.088 11.426
ENSG00000167978 E027 44.9226890 3.430005e-04 1.250534e-01 4.098146e-01 16 2759569 2759661 93 + 1.697 1.625 -0.247
ENSG00000167978 E028 6.8028577 9.032812e-02 7.704197e-01 9.196318e-01 16 2759662 2759746 85 + 0.871 0.899 0.106
ENSG00000167978 E029 23.5398002 9.911217e-03 1.332884e-01 4.229631e-01 16 2759747 2760008 262 + 1.319 1.427 0.373
ENSG00000167978 E030 1.7513835 2.625462e-02 4.685528e-01 7.601025e-01 16 2760009 2760032 24 + 0.369 0.479 0.585
ENSG00000167978 E031 1.1469272 1.661451e-02 1.497457e-01 4.476013e-01 16 2760033 2760058 26 + 0.187 0.409 1.544
ENSG00000167978 E032 23.6945414 1.082886e-02 9.253875e-02 3.493267e-01 16 2760059 2760300 242 + 1.313 1.434 0.418
ENSG00000167978 E033 63.3682884 3.394866e-04 9.392103e-02 3.523769e-01 16 2760301 2760499 199 + 1.841 1.773 -0.230
ENSG00000167978 E034 2.9434233 4.868741e-03 6.758893e-01 8.750186e-01 16 2760500 2760845 346 + 0.625 0.566 -0.263
ENSG00000167978 E035 48.5236372 3.227487e-04 9.574853e-01 9.894624e-01 16 2761561 2761698 138 + 1.690 1.689 -0.006
ENSG00000167978 E036 183.2379478 1.104280e-04 6.592510e-01 8.668054e-01 16 2761699 2762369 671 + 2.256 2.262 0.020
ENSG00000167978 E037 62.1504400 2.288000e-04 4.190064e-03 5.144166e-02 16 2762370 2762600 231 + 1.729 1.837 0.365
ENSG00000167978 E038 475.3671773 7.543091e-04 2.985729e-01 6.260516e-01 16 2762601 2763866 1266 + 2.685 2.663 -0.073
ENSG00000167978 E039 60.4652610 8.641950e-04 2.606299e-01 5.882567e-01 16 2763867 2763938 72 + 1.758 1.800 0.142
ENSG00000167978 E040 314.3101653 4.576661e-04 2.885146e-01 6.160205e-01 16 2763939 2764710 772 + 2.484 2.500 0.054
ENSG00000167978 E041 63.7042727 5.907903e-04 5.315363e-01 7.997601e-01 16 2764711 2764847 137 + 1.793 1.814 0.069
ENSG00000167978 E042 1352.0962809 5.250604e-04 1.069683e-02 9.701332e-02 16 2764848 2767506 2659 + 3.143 3.113 -0.101
ENSG00000167978 E043 271.0970394 6.877441e-05 7.506193e-01 9.106297e-01 16 2767507 2767855 349 + 2.435 2.425 -0.033
ENSG00000167978 E044 194.8417778 1.270761e-04 1.708236e-01 4.789339e-01 16 2767856 2768080 225 + 2.306 2.272 -0.113
ENSG00000167978 E045 163.9725180 6.948297e-04 1.486631e-01 4.456953e-01 16 2768081 2768261 181 + 2.235 2.194 -0.137
ENSG00000167978 E046 10.8419940 3.186933e-02 3.284384e-01 6.525481e-01 16 2768505 2768527 23 + 1.005 1.109 0.377
ENSG00000167978 E047 10.9591702 1.691680e-02 3.358000e-01 6.588173e-01 16 2768528 2768550 23 + 1.017 1.109 0.335
ENSG00000167978 E048 16.2689074 4.273259e-02 1.333762e-01 4.231656e-01 16 2768551 2768599 49 + 1.134 1.291 0.557
ENSG00000167978 E049 23.1056055 2.451386e-03 2.840333e-02 1.783263e-01 16 2768600 2768745 146 + 1.290 1.430 0.486
ENSG00000167978 E050 9.9850564 3.251650e-02 2.376174e-01 5.629059e-01 16 2768746 2768767 22 + 0.956 1.085 0.474
ENSG00000167978 E051 31.4938766 4.321806e-04 1.659642e-04 4.405187e-03 16 2768768 2768996 229 + 1.377 1.581 0.702
ENSG00000167978 E052 248.1031178 1.911812e-03 1.112012e-01 3.853281e-01 16 2768997 2769284 288 + 2.416 2.371 -0.151
ENSG00000167978 E053 24.6170723 6.849829e-04 1.398490e-01 4.328654e-01 16 2769285 2769373 89 + 1.351 1.437 0.298
ENSG00000167978 E054 63.2978606 2.328063e-04 2.486276e-03 3.559311e-02 16 2769374 2769627 254 + 1.733 1.847 0.384
ENSG00000167978 E055 69.3119513 2.157921e-04 1.253774e-10 1.459601e-08 16 2769628 2769861 234 + 1.685 1.927 0.816
ENSG00000167978 E056 109.2609143 1.479320e-04 2.792755e-15 5.954063e-13 16 2769862 2770227 366 + 1.884 2.121 0.795
ENSG00000167978 E057 67.1592551 2.121995e-04 2.159951e-04 5.442011e-03 16 2770228 2770351 124 + 1.744 1.880 0.460
ENSG00000167978 E058 67.9535358 2.080053e-04 3.161936e-01 6.419489e-01 16 2770352 2770354 3 + 1.856 1.815 -0.138
ENSG00000167978 E059 160.9184596 9.988967e-05 8.111953e-01 9.356533e-01 16 2770355 2770465 111 + 2.209 2.200 -0.033
ENSG00000167978 E060 55.9999344 2.455676e-04 3.443445e-01 6.657637e-01 16 2770604 2770606 3 + 1.774 1.732 -0.143
ENSG00000167978 E061 172.6330178 1.026697e-04 2.914930e-03 3.993341e-02 16 2770607 2770717 111 + 2.275 2.202 -0.243
ENSG00000167978 E062 112.6572440 1.734175e-03 5.024680e-01 7.824209e-01 16 2770858 2770910 53 + 2.065 2.039 -0.086
ENSG00000167978 E063 146.9452802 3.856879e-03 2.454253e-01 5.719101e-01 16 2770911 2771049 139 + 2.189 2.145 -0.147
ENSG00000167978 E064 40.7095651 3.777809e-04 7.562509e-02 3.125823e-01 16 2771050 2771120 71 + 1.663 1.576 -0.298
ENSG00000167978 E065 69.0051684 3.906267e-04 4.960765e-01 7.778124e-01 16 2771121 2771277 157 + 1.856 1.827 -0.098
ENSG00000167978 E066 36.3315808 3.832872e-04 1.406383e-01 4.339896e-01 16 2771278 2771303 26 + 1.610 1.532 -0.263
ENSG00000167978 E067 37.5201677 3.868497e-04 8.468094e-02 3.329638e-01 16 2771304 2771368 65 + 1.629 1.541 -0.301
ENSG00000167978 E068 17.3641740 9.007359e-04 6.655692e-01 8.701823e-01 16 2771369 2771603 235 + 1.278 1.244 -0.120
ENSG00000167978 E069 0.0000000       16 2772322 2772538 217 +      

Help

Please Click HERE to learn more details about the results from DEXseq.