ENSG00000168090

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000303904 ENSG00000168090 No_inf pgwt_inf COPS6 protein_coding protein_coding 56.90997 50.56237 65.64963 0.7512873 6.612828 0.3766571 46.328954 38.31404 51.300957 1.909319 1.015861 0.4210171 0.82185833 0.757050 0.802625 0.045575 0.99284725 0.01190815 FALSE TRUE
ENST00000419210 ENSG00000168090 No_inf pgwt_inf COPS6 protein_coding protein_coding 56.90997 50.56237 65.64963 0.7512873 6.612828 0.3766571 3.012402 0.00000 9.037205 0.000000 6.729849 9.8213284 0.03811667 0.000000 0.114350 0.114350 0.99284725 0.01190815 FALSE FALSE
ENST00000496358 ENSG00000168090 No_inf pgwt_inf COPS6 protein_coding retained_intron 56.90997 50.56237 65.64963 0.7512873 6.612828 0.3766571 1.754708 3.31406 0.000000 1.667871 0.000000 -8.3768025 0.03425000 0.066875 0.000000 -0.066875 0.01190815 0.01190815 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000168090 E001 0.8169578 0.0128044409 0.082222941 0.32786653 7 100088969 100088974 6 + 0.370 0.103 -2.327
ENSG00000168090 E002 1.6510208 0.0096467889 0.064019031 0.28532569 7 100088975 100088980 6 + 0.539 0.256 -1.617
ENSG00000168090 E003 2.2739696 0.0117116351 0.227107347 0.55178580 7 100088981 100088981 1 + 0.592 0.416 -0.858
ENSG00000168090 E004 8.3084523 0.0294019810 0.180842302 0.49362809 7 100088982 100088989 8 + 1.036 0.886 -0.558
ENSG00000168090 E005 8.4230471 0.0289586601 0.155512604 0.45655092 7 100088990 100088992 3 + 1.044 0.886 -0.590
ENSG00000168090 E006 26.4129816 0.0039985921 0.648194462 0.86160598 7 100088993 100089053 61 + 1.424 1.452 0.097
ENSG00000168090 E007 27.6377856 0.0027447460 0.602459660 0.83865176 7 100089054 100089066 13 + 1.442 1.472 0.104
ENSG00000168090 E008 19.2619090 0.0009355143 0.295666372 0.62368506 7 100089290 100089292 3 + 1.272 1.340 0.239
ENSG00000168090 E009 47.8281693 0.0003258783 0.546741575 0.80898873 7 100089293 100089415 123 + 1.701 1.675 -0.089
ENSG00000168090 E010 0.2462566 0.0162482191 0.888702733   7 100089416 100089614 199 + 0.088 0.103 0.257
ENSG00000168090 E011 63.6682361 0.0004730226 0.595583315 0.83534524 7 100089615 100089746 132 + 1.821 1.800 -0.069
ENSG00000168090 E012 6.8439645 0.0024756102 0.032834701 0.19410501 7 100089747 100090361 615 + 0.773 0.993 0.843
ENSG00000168090 E013 1.4386679 0.0092907261 0.396376360 0.70891569 7 100090362 100090398 37 + 0.446 0.316 -0.742
ENSG00000168090 E014 28.4076100 0.0016282318 0.332003837 0.65563633 7 100090399 100090427 29 + 1.495 1.439 -0.190
ENSG00000168090 E015 25.1733058 0.0012675312 0.559394172 0.81584812 7 100090428 100090436 9 + 1.435 1.400 -0.121
ENSG00000168090 E016 41.6971947 0.0003474566 0.944980122 0.98613089 7 100090437 100090487 51 + 1.632 1.628 -0.013
ENSG00000168090 E017 1.4103769 0.0093878960 0.014022730 0.11572548 7 100090488 100090591 104 + 0.161 0.533 2.428
ENSG00000168090 E018 44.7693242 0.0003240569 0.109175551 0.38139598 7 100090592 100090654 63 + 1.625 1.694 0.234
ENSG00000168090 E019 2.2938757 0.0245737099 0.007464797 0.07665856 7 100090655 100090901 247 + 0.278 0.676 2.065
ENSG00000168090 E020 36.0769595 0.0004671441 0.493062184 0.77605867 7 100090902 100090949 48 + 1.553 1.585 0.111
ENSG00000168090 E021 2.7166557 0.0236429038 0.425633722 0.73010103 7 100090950 100091037 88 + 0.510 0.625 0.521
ENSG00000168090 E022 60.8032603 0.0002523600 0.775616978 0.92201519 7 100091038 100091152 115 + 1.796 1.785 -0.038
ENSG00000168090 E023 1.8822990 0.0076356140 0.103099379 0.36999297 7 100091153 100091237 85 + 0.326 0.565 1.258
ENSG00000168090 E024 36.1083409 0.0056410529 0.534207637 0.80117774 7 100091238 100091307 70 + 1.587 1.551 -0.123
ENSG00000168090 E025 20.4059203 0.0010884694 0.494625829 0.77676331 7 100091308 100091330 23 + 1.352 1.307 -0.157
ENSG00000168090 E026 47.9578469 0.0002957934 0.584436293 0.82925571 7 100091420 100091520 101 + 1.701 1.677 -0.081
ENSG00000168090 E027 80.6275527 0.0001921508 0.526119334 0.79627423 7 100091649 100092187 539 + 1.902 1.921 0.065

Help

Please Click HERE to learn more details about the results from DEXseq.