ENSG00000168488

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000336783 ENSG00000168488 No_inf pgwt_inf ATXN2L protein_coding protein_coding 67.54451 59.44191 74.18073 3.340869 2.020778 0.3195157 5.345812 3.665321 6.997445 1.2879663 2.967552 0.9310184 0.07939167 0.062275 0.093475 0.031200 1.000000e+00 4.943698e-06 FALSE TRUE
ENST00000340394 ENSG00000168488 No_inf pgwt_inf ATXN2L protein_coding protein_coding 67.54451 59.44191 74.18073 3.340869 2.020778 0.3195157 2.206837 0.000000 3.839382 0.0000000 3.839382 8.5884829 0.03014167 0.000000 0.050650 0.050650 9.932366e-01 4.943698e-06 FALSE TRUE
ENST00000382686 ENSG00000168488 No_inf pgwt_inf ATXN2L protein_coding protein_coding 67.54451 59.44191 74.18073 3.340869 2.020778 0.3195157 4.348497 3.136211 4.654004 1.6597459 1.305700 0.5679537 0.06292500 0.049600 0.062025 0.012425 9.928472e-01 4.943698e-06 FALSE TRUE
ENST00000566946 ENSG00000168488 No_inf pgwt_inf ATXN2L protein_coding protein_coding 67.54451 59.44191 74.18073 3.340869 2.020778 0.3195157 1.714786 3.461142 0.000000 2.0030844 0.000000 -8.4392664 0.02627500 0.054750 0.000000 -0.054750 9.606631e-01 4.943698e-06 FALSE TRUE
MSTRG.10924.12 ENSG00000168488 No_inf pgwt_inf ATXN2L protein_coding   67.54451 59.44191 74.18073 3.340869 2.020778 0.3195157 8.204123 14.985458 6.896444 3.5312630 3.308658 -1.1185106 0.13060000 0.264175 0.090625 -0.173550 9.716538e-01 4.943698e-06 FALSE TRUE
MSTRG.10924.13 ENSG00000168488 No_inf pgwt_inf ATXN2L protein_coding   67.54451 59.44191 74.18073 3.340869 2.020778 0.3195157 7.361800 0.000000 13.673686 0.0000000 4.858891 10.4182412 0.10176667 0.000000 0.187625 0.187625 1.914310e-01 4.943698e-06 FALSE TRUE
MSTRG.10924.17 ENSG00000168488 No_inf pgwt_inf ATXN2L protein_coding   67.54451 59.44191 74.18073 3.340869 2.020778 0.3195157 4.078190 5.956729 0.000000 0.4313118 0.000000 -9.2207965 0.06593333 0.101425 0.000000 -0.101425 4.943698e-06 4.943698e-06 FALSE TRUE
MSTRG.10924.24 ENSG00000168488 No_inf pgwt_inf ATXN2L protein_coding   67.54451 59.44191 74.18073 3.340869 2.020778 0.3195157 8.627578 7.522412 11.814493 1.5445404 1.605625 0.6505945 0.12494167 0.123025 0.157975 0.034950 9.928472e-01 4.943698e-06 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000168488 E001 0.0000000       16 28822999 28823005 7 +      
ENSG00000168488 E002 0.0000000       16 28823006 28823018 13 +      
ENSG00000168488 E003 0.0000000       16 28823019 28823034 16 +      
ENSG00000168488 E004 0.0000000       16 28823035 28823047 13 +      
ENSG00000168488 E005 0.0000000       16 28823048 28823077 30 +      
ENSG00000168488 E006 0.0000000       16 28823078 28823092 15 +      
ENSG00000168488 E007 0.0000000       16 28823093 28823094 2 +      
ENSG00000168488 E008 0.0000000       16 28823095 28823251 157 +      
ENSG00000168488 E009 0.0000000       16 28823252 28823481 230 +      
ENSG00000168488 E010 0.0000000       16 28823482 28823558 77 +      
ENSG00000168488 E011 1.6660532 0.0419624316 0.311562951 0.63767055 16 28824138 28824450 313 + 0.492 0.330 -0.886
ENSG00000168488 E012 1.5527042 0.0085262557 0.386356747 0.70097538 16 28824451 28824542 92 + 0.462 0.330 -0.734
ENSG00000168488 E013 0.3422067 0.0326425345 0.177714218   16 28824543 28824661 119 + 0.213 0.000 -11.537
ENSG00000168488 E014 2.0268022 0.0079090056 0.269197547 0.59723424 16 28825366 28825370 5 + 0.547 0.385 -0.827
ENSG00000168488 E015 6.5073927 0.0034684642 0.415163096 0.72256888 16 28825371 28825402 32 + 0.912 0.826 -0.330
ENSG00000168488 E016 13.1824154 0.0014187454 0.511765159 0.78753414 16 28825624 28825680 57 + 1.173 1.122 -0.182
ENSG00000168488 E017 0.2453209 0.0163286015 0.816749905   16 28825681 28825769 89 + 0.083 0.109 0.436
ENSG00000168488 E018 26.6799645 0.0005308445 0.024196965 0.16208455 16 28825770 28825841 72 + 1.496 1.366 -0.449
ENSG00000168488 E019 0.9987691 0.0120530724 0.263199116 0.59128120 16 28825842 28826184 343 + 0.213 0.384 1.173
ENSG00000168488 E020 53.5461980 0.0007260093 0.036472107 0.20738628 16 28826240 28826390 151 + 1.773 1.686 -0.294
ENSG00000168488 E021 1.1918358 0.0439372581 0.431201876 0.73403315 16 28826391 28826605 215 + 0.393 0.268 -0.787
ENSG00000168488 E022 30.5519155 0.0013438629 0.183098919 0.49601905 16 28826862 28826923 62 + 1.529 1.457 -0.250
ENSG00000168488 E023 34.0956662 0.0005477526 0.274903633 0.60283516 16 28826924 28826986 63 + 1.568 1.513 -0.187
ENSG00000168488 E024 45.7642875 0.0005893250 0.112022039 0.38700958 16 28829401 28829492 92 + 1.699 1.629 -0.238
ENSG00000168488 E025 1.1659984 0.0372217237 0.005147127 0.05945689 16 28829778 28829857 80 + 0.083 0.516 3.436
ENSG00000168488 E026 21.5344520 0.0020320734 0.480185830 0.76778245 16 28829858 28829868 11 + 1.371 1.327 -0.156
ENSG00000168488 E027 46.2317502 0.0003237207 0.593911506 0.83448166 16 28829869 28830058 190 + 1.661 1.686 0.085
ENSG00000168488 E028 50.6673380 0.0003161465 0.217701253 0.54085028 16 28830615 28830790 176 + 1.734 1.684 -0.172
ENSG00000168488 E029 0.3936739 0.0159143286 0.057377655   16 28830791 28830961 171 + 0.000 0.268 12.207
ENSG00000168488 E030 25.2871945 0.0005389900 0.082130597 0.32759673 16 28830962 28830984 23 + 1.462 1.360 -0.352
ENSG00000168488 E031 46.3773655 0.0073838779 0.239240935 0.56496469 16 28830985 28831072 88 + 1.703 1.638 -0.221
ENSG00000168488 E032 1.7001510 0.2472870809 0.909399965 0.97321654 16 28832187 28832204 18 + 0.429 0.433 0.022
ENSG00000168488 E033 92.2376822 0.0002330238 0.194302833 0.51040429 16 28832205 28832399 195 + 1.986 1.947 -0.132
ENSG00000168488 E034 44.8218575 0.0005887878 0.930973040 0.98076313 16 28832496 28832567 72 + 1.657 1.663 0.019
ENSG00000168488 E035 49.4401496 0.0014938005 0.948370457 0.98687041 16 28832817 28832887 71 + 1.699 1.704 0.015
ENSG00000168488 E036 72.2436666 0.0002682631 0.301576904 0.62879071 16 28833059 28833195 137 + 1.845 1.883 0.128
ENSG00000168488 E037 79.9575961 0.0008758546 0.069280621 0.29828313 16 28833196 28833354 159 + 1.876 1.941 0.220
ENSG00000168488 E038 53.8030516 0.0002679494 0.172823728 0.48198436 16 28833439 28833508 70 + 1.710 1.767 0.193
ENSG00000168488 E039 2.4384783 0.0806818732 0.908209544 0.97288513 16 28833856 28834064 209 + 0.520 0.552 0.147
ENSG00000168488 E040 82.0405044 0.0001725536 0.782711114 0.92479942 16 28834065 28834211 147 + 1.913 1.924 0.036
ENSG00000168488 E041 0.1311489 0.0122572732 0.396927437   16 28834329 28834342 14 + 0.000 0.109 10.622
ENSG00000168488 E042 52.2264804 0.0002958921 0.172096950 0.48091481 16 28834343 28834415 73 + 1.749 1.694 -0.188
ENSG00000168488 E043 33.1682007 0.0004118248 0.928830620 0.98015705 16 28834506 28834522 17 + 1.529 1.536 0.021
ENSG00000168488 E044 92.2931422 0.0027825692 0.992412642 1.00000000 16 28834523 28834693 171 + 1.967 1.970 0.008
ENSG00000168488 E045 1.6193273 0.0136972837 0.178911489 0.49116695 16 28834852 28835057 206 + 0.312 0.516 1.114
ENSG00000168488 E046 40.9938997 0.0004022718 0.254203482 0.58124763 16 28835058 28835098 41 + 1.645 1.593 -0.177
ENSG00000168488 E047 65.9752102 0.0002147179 0.880027790 0.96204070 16 28835099 28835187 89 + 1.821 1.828 0.024
ENSG00000168488 E048 1.3579652 0.0101501740 0.431711593 0.73438144 16 28835188 28835277 90 + 0.312 0.433 0.699
ENSG00000168488 E049 65.9553905 0.0002573692 0.477817956 0.76596814 16 28835278 28835399 122 + 1.811 1.839 0.094
ENSG00000168488 E050 2.2724379 0.0469191361 0.383784482 0.69949815 16 28835400 28835545 146 + 0.572 0.433 -0.680
ENSG00000168488 E051 4.0412977 0.0159293742 0.518338946 0.79161511 16 28835546 28835548 3 + 0.661 0.745 0.348
ENSG00000168488 E052 16.5820111 0.0032468916 0.583261306 0.82857475 16 28835549 28835554 6 + 1.262 1.222 -0.140
ENSG00000168488 E053 30.4976712 0.0076514756 0.516644972 0.79077102 16 28835555 28835594 40 + 1.516 1.474 -0.144
ENSG00000168488 E054 44.0155460 0.0080181553 0.792629877 0.92855864 16 28835595 28835668 74 + 1.645 1.660 0.051
ENSG00000168488 E055 48.1840826 0.0024458701 0.433305724 0.73589058 16 28835669 28835758 90 + 1.707 1.671 -0.122
ENSG00000168488 E056 69.3792844 0.0002903598 0.695606890 0.88426429 16 28835933 28836122 190 + 1.852 1.839 -0.043
ENSG00000168488 E057 16.5295466 0.0008270062 0.010252083 0.09427672 16 28836123 28836176 54 + 1.148 1.332 0.652
ENSG00000168488 E058 33.0740349 0.0018427188 0.006087973 0.06658141 16 28836177 28836325 149 + 1.456 1.605 0.511
ENSG00000168488 E059 40.6527218 0.0003747368 0.180026292 0.49251235 16 28836326 28836445 120 + 1.587 1.652 0.219
ENSG00000168488 E060 13.1460446 0.0012902453 0.002274662 0.03338267 16 28836446 28836448 3 + 1.020 1.264 0.875
ENSG00000168488 E061 20.7400735 0.0117516287 0.489248944 0.77387213 16 28836449 28836485 37 + 1.309 1.366 0.198
ENSG00000168488 E062 10.5494780 0.0299470335 0.301543352 0.62878979 16 28836486 28836490 5 + 1.002 1.122 0.436
ENSG00000168488 E063 55.6735095 0.0081851410 0.008804302 0.08536716 16 28836491 28836727 237 + 1.679 1.825 0.493
ENSG00000168488 E064 31.6728157 0.0013410673 0.523206928 0.79451045 16 28836728 28836747 20 + 1.496 1.532 0.124
ENSG00000168488 E065 22.9682573 0.0090014432 0.956356220 0.98930820 16 28836748 28836750 3 + 1.375 1.381 0.021
ENSG00000168488 E066 55.4638350 0.0002520682 0.389307678 0.70283242 16 28836751 28836849 99 + 1.765 1.732 -0.112
ENSG00000168488 E067 32.0132568 0.0043722364 0.781006896 0.92415871 16 28836850 28837237 388 + 1.524 1.510 -0.049

Help

Please Click HERE to learn more details about the results from DEXseq.