ENSG00000168591

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000319511 ENSG00000168591 No_inf pgwt_inf TMUB2 protein_coding protein_coding 21.55903 22.02155 21.24953 1.050431 0.4901152 -0.05146161 2.8292729 2.1670292 3.191915 0.8976064 1.2539606 0.5565741 0.13032500 0.093350 0.153525 0.060175 0.992847247 0.007010414 FALSE  
ENST00000446571 ENSG00000168591 No_inf pgwt_inf TMUB2 protein_coding protein_coding 21.55903 22.02155 21.24953 1.050431 0.4901152 -0.05146161 1.6378198 2.6099697 1.476438 0.9529147 1.0621716 -0.8176911 0.07601667 0.120475 0.072400 -0.048075 0.992847247 0.007010414 FALSE  
ENST00000587326 ENSG00000168591 No_inf pgwt_inf TMUB2 protein_coding nonsense_mediated_decay 21.55903 22.02155 21.24953 1.050431 0.4901152 -0.05146161 0.9990304 1.9282800 0.000000 0.2596710 0.0000000 -7.5986332 0.04680000 0.088600 0.000000 -0.088600 0.007010414 0.007010414 FALSE  
ENST00000589856 ENSG00000168591 No_inf pgwt_inf TMUB2 protein_coding protein_coding 21.55903 22.02155 21.24953 1.050431 0.4901152 -0.05146161 2.7950262 3.2526538 2.685645 0.3007476 0.4098597 -0.2754156 0.13029167 0.147000 0.125775 -0.021225 0.993236612 0.007010414 FALSE  
MSTRG.12757.5 ENSG00000168591 No_inf pgwt_inf TMUB2 protein_coding   21.55903 22.02155 21.24953 1.050431 0.4901152 -0.05146161 1.7034150 2.1738086 1.940026 0.9630234 0.3089823 -0.1633534 0.08013333 0.098825 0.092275 -0.006550 1.000000000 0.007010414 FALSE  
MSTRG.12757.8 ENSG00000168591 No_inf pgwt_inf TMUB2 protein_coding   21.55903 22.02155 21.24953 1.050431 0.4901152 -0.05146161 5.1545990 6.9096902 4.501335 0.8879494 1.6062450 -0.6171529 0.24328333 0.319625 0.207325 -0.112300 0.992847247 0.007010414 FALSE  
MSTRG.12757.9 ENSG00000168591 No_inf pgwt_inf TMUB2 protein_coding   21.55903 22.02155 21.24953 1.050431 0.4901152 -0.05146161 2.5713515 0.8763098 4.114196 0.5076763 0.9433214 2.2182299 0.11965833 0.042150 0.194800 0.152650 0.683606597 0.007010414 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000168591 E001 0.0000000       17 44186970 44186971 2 +      
ENSG00000168591 E002 0.2279004 0.2291705919 0.267186912   17 44186972 44186985 14 + 0.178 0.000 -9.540
ENSG00000168591 E003 0.3424952 0.0289075710 0.091740869   17 44186986 44187005 20 + 0.246 0.000 -12.927
ENSG00000168591 E004 0.8502608 0.0140522606 0.638935139 0.85676604 17 44187006 44187012 7 + 0.305 0.232 -0.521
ENSG00000168591 E005 1.7522026 0.0105479035 0.355402959 0.67545902 17 44187013 44187048 36 + 0.356 0.495 0.742
ENSG00000168591 E006 1.8661528 0.0108622587 0.532940428 0.80056136 17 44187049 44187049 1 + 0.402 0.495 0.479
ENSG00000168591 E007 4.0548818 0.1032908320 0.933960611 0.98170903 17 44187050 44187109 60 + 0.704 0.700 -0.018
ENSG00000168591 E008 1.4889011 0.0092342251 0.653207052 0.86449999 17 44187110 44187190 81 + 0.356 0.424 0.379
ENSG00000168591 E009 0.9827256 0.0125572573 0.919829057 0.97675719 17 44187191 44187205 15 + 0.305 0.289 -0.106
ENSG00000168591 E010 2.4380785 0.0927796331 0.607916351 0.84157167 17 44187206 44187233 28 + 0.579 0.495 -0.396
ENSG00000168591 E011 3.9291612 0.0149127971 0.841157132 0.94747751 17 44187234 44187261 28 + 0.705 0.679 -0.106
ENSG00000168591 E012 4.2544478 0.0222311267 0.327989053 0.65221020 17 44187262 44187271 10 + 0.784 0.657 -0.521
ENSG00000168591 E013 4.2364633 0.0036263845 0.165887318 0.47183316 17 44187272 44187274 3 + 0.802 0.634 -0.691
ENSG00000168591 E014 11.9543115 0.0012135737 0.007286878 0.07553864 17 44187275 44187400 126 + 1.217 0.999 -0.789
ENSG00000168591 E015 5.2179382 0.0030771101 0.195766928 0.51255095 17 44187401 44187431 31 + 0.866 0.720 -0.580
ENSG00000168591 E016 12.0323531 0.0012725262 0.239903322 0.56569572 17 44187432 44187616 185 + 1.057 1.153 0.343
ENSG00000168591 E017 5.8092795 0.0202049406 0.657645312 0.86633974 17 44187617 44187653 37 + 0.802 0.853 0.202
ENSG00000168591 E018 4.4511237 0.0037119081 0.652442546 0.86409806 17 44187654 44187675 22 + 0.705 0.757 0.216
ENSG00000168591 E019 9.0152366 0.0164540705 0.624813255 0.84981417 17 44187676 44187743 68 + 0.972 1.019 0.171
ENSG00000168591 E020 4.9413802 0.0030271586 0.686133135 0.88034689 17 44187907 44187931 25 + 0.746 0.792 0.183
ENSG00000168591 E021 8.6638034 0.0016626370 0.012589756 0.10795345 17 44187932 44188009 78 + 0.835 1.074 0.894
ENSG00000168591 E022 1.0343286 0.0132949434 0.033943522 0.19827529 17 44188851 44188903 53 + 0.098 0.424 2.701
ENSG00000168591 E023 0.9029604 0.0124998083 0.061047306 0.27807762 17 44188904 44188932 29 + 0.098 0.383 2.479
ENSG00000168591 E024 0.6405823 0.0150254223 0.199137677 0.51705935 17 44188933 44188934 2 + 0.098 0.289 1.894
ENSG00000168591 E025 11.2010133 0.0013560630 0.117895844 0.39739785 17 44188935 44189021 87 + 1.006 1.138 0.479
ENSG00000168591 E026 14.0393692 0.0014913589 0.858190920 0.95428521 17 44189022 44189083 62 + 1.168 1.181 0.046
ENSG00000168591 E027 9.1807177 0.0017572331 0.277722497 0.60584247 17 44189084 44189091 8 + 0.948 1.047 0.366
ENSG00000168591 E028 16.3942036 0.0008932473 0.711397971 0.89274872 17 44189092 44189203 112 + 1.224 1.249 0.089
ENSG00000168591 E029 4.5303049 0.0032430917 0.706164406 0.89020550 17 44189204 44189206 3 + 0.765 0.720 -0.184
ENSG00000168591 E030 14.2246684 0.0010803838 0.404469931 0.71469888 17 44189207 44189299 93 + 1.145 1.207 0.221
ENSG00000168591 E031 11.7829348 0.0012165895 0.723362521 0.89848669 17 44189300 44189369 70 + 1.120 1.091 -0.106
ENSG00000168591 E032 9.7489666 0.0014610077 0.223861138 0.54813911 17 44189370 44189410 41 + 1.086 0.977 -0.396
ENSG00000168591 E033 8.0664082 0.0018120534 0.433561273 0.73611264 17 44189411 44189423 13 + 0.995 0.920 -0.281
ENSG00000168591 E034 22.7063743 0.0006474465 0.675071483 0.87460268 17 44189424 44189588 165 + 1.387 1.361 -0.091
ENSG00000168591 E035 6.8893660 0.0021265791 0.998984229 1.00000000 17 44189589 44190349 761 + 0.895 0.894 -0.003
ENSG00000168591 E036 30.1182612 0.0005407232 0.271018380 0.59889613 17 44190501 44190635 135 + 1.522 1.464 -0.200
ENSG00000168591 E037 34.1312170 0.0004800420 0.621424825 0.84803590 17 44190636 44190886 251 + 1.557 1.532 -0.086
ENSG00000168591 E038 33.0392953 0.0004267374 0.676114978 0.87512166 17 44190887 44191105 219 + 1.541 1.520 -0.074
ENSG00000168591 E039 77.3899162 0.0002966180 0.497240844 0.77863566 17 44191106 44191929 824 + 1.880 1.901 0.068

Help

Please Click HERE to learn more details about the results from DEXseq.