ENSG00000168685

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000303115 ENSG00000168685 No_inf pgwt_inf IL7R protein_coding protein_coding 31.42978 68.27629 10.78117 2.272535 0.2731291 -2.661745 11.0108231 23.115366 3.0560659 1.285560 0.9110807 -2.915016 0.36045000 0.340750 0.283000 -0.057750 0.9928472467 0.0001098174 FALSE TRUE
ENST00000505093 ENSG00000168685 No_inf pgwt_inf IL7R protein_coding protein_coding 31.42978 68.27629 10.78117 2.272535 0.2731291 -2.661745 5.5765198 8.879799 2.3529711 5.143461 1.3983252 -1.911549 0.23655833 0.132900 0.223125 0.090225 1.0000000000 0.0001098174   FALSE
ENST00000505875 ENSG00000168685 No_inf pgwt_inf IL7R protein_coding retained_intron 31.42978 68.27629 10.78117 2.272535 0.2731291 -2.661745 9.1200356 24.777291 2.5828157 5.320984 1.5295879 -3.257009 0.19770000 0.358050 0.235050 -0.123000 0.9928472467 0.0001098174 FALSE TRUE
ENST00000506850 ENSG00000168685 No_inf pgwt_inf IL7R protein_coding protein_coding 31.42978 68.27629 10.78117 2.272535 0.2731291 -2.661745 2.7157454 7.055131 0.0000000 1.168294 0.0000000 -9.464573 0.05699167 0.102225 0.000000 -0.102225 0.0289330719 0.0001098174 FALSE TRUE
ENST00000514217 ENSG00000168685 No_inf pgwt_inf IL7R protein_coding nonsense_mediated_decay 31.42978 68.27629 10.78117 2.272535 0.2731291 -2.661745 1.8579269 2.771148 1.0206795 1.198782 1.0206795 -1.432085 0.08658333 0.042025 0.097700 0.055675 0.9928472467 0.0001098174 FALSE TRUE
ENST00000515665 ENSG00000168685 No_inf pgwt_inf IL7R protein_coding protein_coding 31.42978 68.27629 10.78117 2.272535 0.2731291 -2.661745 0.2027865 0.000000 0.6083596 0.000000 0.4493838 5.950374 0.01789167 0.000000 0.053675 0.053675 0.4949249602 0.0001098174   FALSE
MSTRG.22781.6 ENSG00000168685 No_inf pgwt_inf IL7R protein_coding   31.42978 68.27629 10.78117 2.272535 0.2731291 -2.661745 0.3867589 0.000000 1.1602767 0.000000 0.3168368 6.870706 0.03580833 0.000000 0.107425 0.107425 0.0001098174 0.0001098174 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000168685 E001 0.0000000       5 35852695 35852722 28 +      
ENSG00000168685 E002 0.0000000       5 35852723 35852938 216 +      
ENSG00000168685 E003 0.0000000       5 35856032 35856169 138 +      
ENSG00000168685 E004 0.0000000       5 35856295 35856687 393 +      
ENSG00000168685 E005 0.3768359 1.932598e-01 0.336363045   5 35856889 35856890 2 + 0.205 0.079 -1.608
ENSG00000168685 E006 0.3768359 1.932598e-01 0.336363045   5 35856891 35856891 1 + 0.205 0.079 -1.608
ENSG00000168685 E007 8.8379358 1.974578e-03 0.277385751 0.6055904 5 35856892 35856976 85 + 0.947 0.816 -0.501
ENSG00000168685 E008 14.8086938 9.531128e-04 0.829484612 0.9425961 5 35856977 35857059 83 + 1.052 1.030 -0.081
ENSG00000168685 E009 16.1633035 8.638934e-04 0.002482384 0.0355585 5 35860852 35860964 113 + 0.719 1.100 1.455
ENSG00000168685 E010 8.3191779 1.709720e-03 0.120640637 0.4019727 5 35860965 35860990 26 + 0.605 0.836 0.952
ENSG00000168685 E011 22.4125678 8.663911e-04 0.146508806 0.4426113 5 35867306 35867463 158 + 1.075 1.214 0.498
ENSG00000168685 E012 0.2622978 2.530150e-01 1.000000000   5 35867464 35867610 147 + 0.000 0.079 7.839
ENSG00000168685 E013 20.7465316 6.774057e-04 0.939326463 0.9839669 5 35871056 35871213 158 + 1.173 1.167 -0.023
ENSG00000168685 E014 1.8385321 1.423804e-01 0.145527823 0.4411910 5 35873201 35873479 279 + 0.000 0.378 10.659
ENSG00000168685 E015 12.7194786 1.664811e-03 0.559243961 0.8158292 5 35873480 35873533 54 + 1.028 0.965 -0.233
ENSG00000168685 E016 17.0460673 1.602258e-02 0.264176273 0.5922085 5 35873534 35873648 115 + 1.191 1.072 -0.425
ENSG00000168685 E017 15.8438467 3.694349e-03 0.862387962 0.9558430 5 35874449 35874542 94 + 1.075 1.057 -0.064
ENSG00000168685 E018 2.2144119 7.070170e-03 0.290578484 0.6185903 5 35875414 35875511 98 + 0.205 0.413 1.392
ENSG00000168685 E019 19.9279059 9.816577e-03 0.514454166 0.7894067 5 35875512 35875587 76 + 1.207 1.143 -0.230
ENSG00000168685 E020 4.5439185 3.188903e-03 0.319446378 0.6446488 5 35875588 35875722 135 + 0.449 0.620 0.807
ENSG00000168685 E021 734.4169780 6.601865e-05 0.393486316 0.7066652 5 35875983 35879603 3621 + 2.692 2.686 -0.019

Help

Please Click HERE to learn more details about the results from DEXseq.