ENSG00000169689

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000306704 ENSG00000169689 No_inf pgwt_inf CENPX protein_coding protein_coding 34.55312 30.83707 35.2952 1.1859 1.421773 0.1947473 14.096133 15.8072318 13.697881 2.7315374 5.6349129 -0.2064916 0.41670000 0.505875 0.397325 -0.108550 0.9928472467 0.0005548503   FALSE
ENST00000392359 ENSG00000169689 No_inf pgwt_inf CENPX protein_coding protein_coding 34.55312 30.83707 35.2952 1.1859 1.421773 0.1947473 8.030557 7.3938566 8.127612 2.6501793 4.3447126 0.1363285 0.22815000 0.245450 0.220875 -0.024575 1.0000000000 0.0005548503 FALSE FALSE
ENST00000577379 ENSG00000169689 No_inf pgwt_inf CENPX protein_coding protein_coding_CDS_not_defined 34.55312 30.83707 35.2952 1.1859 1.421773 0.1947473 3.362549 2.6991357 5.006776 0.3549457 0.8579724 0.8889279 0.09690000 0.089100 0.140550 0.051450 0.9928472467 0.0005548503   FALSE
ENST00000580435 ENSG00000169689 No_inf pgwt_inf CENPX protein_coding protein_coding 34.55312 30.83707 35.2952 1.1859 1.421773 0.1947473 2.643519 0.9035208 2.819707 0.5929233 2.3870223 1.6311433 0.07057500 0.030700 0.073300 0.042600 1.0000000000 0.0005548503   FALSE
ENST00000584600 ENSG00000169689 No_inf pgwt_inf CENPX protein_coding protein_coding 34.55312 30.83707 35.2952 1.1859 1.421773 0.1947473 1.823452 0.0000000 2.121377 0.0000000 2.1213766 7.7356417 0.05553333 0.000000 0.065800 0.065800 0.9928472467 0.0005548503   FALSE
MSTRG.13484.11 ENSG00000169689 No_inf pgwt_inf CENPX protein_coding   34.55312 30.83707 35.2952 1.1859 1.421773 0.1947473 1.397871 3.2683238 0.000000 0.7936116 0.0000000 -8.3568146 0.04281667 0.104600 0.000000 -0.104600 0.0005548503 0.0005548503 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000169689 E001 0.000000       17 82018702 82018702 1 -      
ENSG00000169689 E002 1.639490 0.0093690815 0.092686792 0.34975647 17 82018703 82018715 13 - 0.279 0.531 1.412
ENSG00000169689 E003 9.938378 0.0014502732 0.019220105 0.14045799 17 82018716 82018800 85 - 0.926 1.131 0.753
ENSG00000169689 E004 12.993184 0.0015547088 0.030962649 0.18784950 17 82018801 82018837 37 - 1.055 1.223 0.602
ENSG00000169689 E005 9.358240 0.0090781029 0.263210316 0.59128120 17 82018838 82018843 6 - 0.959 1.066 0.395
ENSG00000169689 E006 10.717236 0.0016814309 0.185357822 0.49910755 17 82018844 82018865 22 - 1.010 1.122 0.409
ENSG00000169689 E007 45.186355 0.0003847637 0.783200507 0.92486235 17 82018866 82019156 291 - 1.659 1.670 0.040
ENSG00000169689 E008 19.218004 0.0008800596 0.070613677 0.30148645 17 82019157 82019219 63 - 1.358 1.243 -0.403
ENSG00000169689 E009 4.741388 0.0030556547 0.777035884 0.92266470 17 82019220 82019292 73 - 0.775 0.743 -0.129
ENSG00000169689 E010 15.509560 0.0009618369 0.889833804 0.96610290 17 82019293 82019307 15 - 1.212 1.223 0.038
ENSG00000169689 E011 23.973746 0.0006177205 0.614293027 0.84469664 17 82019308 82019381 74 - 1.411 1.383 -0.095
ENSG00000169689 E012 2.688857 0.0057315644 0.001014077 0.01816851 17 82019382 82019509 128 - 0.279 0.743 2.331
ENSG00000169689 E013 2.534846 0.0500981980 0.494924979 0.77695719 17 82019510 82019640 131 - 0.594 0.496 -0.457
ENSG00000169689 E014 8.171405 0.0019793740 0.075888480 0.31319411 17 82019641 82019694 54 - 1.037 0.869 -0.631
ENSG00000169689 E015 1.061343 0.0132305576 0.144924116 0.44048103 17 82019695 82019857 163 - 0.411 0.185 -1.564
ENSG00000169689 E016 14.957102 0.0009940861 0.066226336 0.29120894 17 82019858 82019909 52 - 1.263 1.131 -0.469
ENSG00000169689 E017 4.052580 0.0036605784 0.051210940 0.25122466 17 82022639 82022825 187 - 0.806 0.564 -1.020
ENSG00000169689 E018 10.415781 0.0013821597 0.328618260 0.65261415 17 82022826 82022918 93 - 1.096 1.014 -0.300
ENSG00000169689 E019 0.000000       17 82024065 82024107 43 -      

Help

Please Click HERE to learn more details about the results from DEXseq.