ENSG00000169919

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000304895 ENSG00000169919 No_inf pgwt_inf GUSB protein_coding protein_coding 69.94145 88.33179 65.163 0.7016952 1.090768 -0.4388217 4.698853 2.049877 5.2503777 2.049877 5.2503777 1.3526082 0.07544167 0.022825 0.081125 0.058300 1.000000e+00 2.70426e-06 FALSE TRUE
ENST00000421103 ENSG00000169919 No_inf pgwt_inf GUSB protein_coding protein_coding 69.94145 88.33179 65.163 0.7016952 1.090768 -0.4388217 6.748022 14.526719 0.0000000 2.873495 0.0000000 -10.5054860 0.08885000 0.164475 0.000000 -0.164475 2.704260e-06 2.70426e-06 FALSE TRUE
ENST00000430730 ENSG00000169919 No_inf pgwt_inf GUSB protein_coding nonsense_mediated_decay 69.94145 88.33179 65.163 0.7016952 1.090768 -0.4388217 10.383049 10.372765 12.9014332 3.970117 4.5221914 0.3144584 0.15113333 0.117400 0.196700 0.079300 9.932366e-01 2.70426e-06 FALSE TRUE
ENST00000447929 ENSG00000169919 No_inf pgwt_inf GUSB protein_coding nonsense_mediated_decay 69.94145 88.33179 65.163 0.7016952 1.090768 -0.4388217 2.814156 6.976709 0.3402743 3.417039 0.3402743 -4.3180561 0.03510833 0.079700 0.005450 -0.074250 8.086731e-01 2.70426e-06 FALSE TRUE
MSTRG.26258.1 ENSG00000169919 No_inf pgwt_inf GUSB protein_coding   69.94145 88.33179 65.163 0.7016952 1.090768 -0.4388217 38.936575 47.616916 38.1165477 1.985097 1.8976254 -0.3209812 0.55780000 0.538700 0.584525 0.045825 9.928472e-01 2.70426e-06 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000169919 E001 0.0000000       7 65960684 65960687 4 -      
ENSG00000169919 E002 0.0000000       7 65960688 65960688 1 -      
ENSG00000169919 E003 0.1316618 1.221395e-02 7.501566e-01   7 65960689 65960690 2 - 0.000 0.082 8.441
ENSG00000169919 E004 0.5087816 1.965905e-02 5.051857e-01   7 65960691 65960692 2 - 0.110 0.210 1.102
ENSG00000169919 E005 2.3401859 7.251509e-03 6.291212e-01 0.851543252 7 65960693 65960697 5 - 0.557 0.487 -0.331
ENSG00000169919 E006 2.4713348 6.032148e-03 7.748604e-01 0.921655254 7 65960698 65960700 3 - 0.557 0.516 -0.193
ENSG00000169919 E007 9.6485647 1.449868e-03 2.311284e-01 0.556852160 7 65960701 65960741 41 - 0.945 1.055 0.406
ENSG00000169919 E008 208.7518806 9.117419e-05 3.103929e-05 0.001113346 7 65960742 65961063 322 - 2.257 2.339 0.275
ENSG00000169919 E009 0.5079830 2.830446e-02 5.068264e-01   7 65964146 65964322 177 - 0.110 0.210 1.102
ENSG00000169919 E010 55.6289719 3.440180e-04 4.502533e-01 0.748028969 7 65964323 65964329 7 - 1.723 1.752 0.100
ENSG00000169919 E011 102.9321836 1.585413e-04 9.142460e-01 0.974669447 7 65964330 65964458 129 - 2.004 2.005 0.006
ENSG00000169919 E012 116.1133815 2.387380e-03 5.531574e-01 0.812644645 7 65967731 65967907 177 - 2.045 2.063 0.061
ENSG00000169919 E013 0.0000000       7 65967908 65967908 1 -      
ENSG00000169919 E014 72.8132843 1.561605e-03 1.557248e-01 0.456881122 7 65970282 65970366 85 - 1.822 1.876 0.181
ENSG00000169919 E015 0.1145948 1.117340e-02 3.832745e-01   7 65974294 65974294 1 - 0.110 0.000 -12.224
ENSG00000169919 E016 64.4420774 4.538284e-04 9.348336e-01 0.982054552 7 65974295 65974356 62 - 1.803 1.805 0.006
ENSG00000169919 E017 55.8341693 5.737120e-04 9.330464e-01 0.981431287 7 65974357 65974401 45 - 1.746 1.741 -0.017
ENSG00000169919 E018 32.2472579 9.568427e-04 8.705910e-01 0.959257355 7 65974402 65974403 2 - 1.516 1.506 -0.035
ENSG00000169919 E019 45.5252375 8.819520e-03 8.969279e-01 0.969152426 7 65974404 65974441 38 - 1.661 1.652 -0.031
ENSG00000169919 E020 1.9354091 9.195369e-03 1.770193e-02 0.134246384 7 65974442 65974502 61 - 0.198 0.567 2.218
ENSG00000169919 E021 1.5413771 1.690104e-02 6.723139e-02 0.293697372 7 65974503 65974525 23 - 0.198 0.487 1.839
ENSG00000169919 E022 83.4787527 2.323883e-04 1.818853e-01 0.494546435 7 65974526 65974704 179 - 1.942 1.897 -0.152
ENSG00000169919 E023 5.2593757 3.163078e-03 4.269525e-01 0.731041162 7 65974705 65974918 214 - 0.728 0.819 0.365
ENSG00000169919 E024 20.6140100 6.754440e-04 2.079866e-01 0.528552032 7 65974919 65975011 93 - 1.271 1.353 0.287
ENSG00000169919 E025 17.4952294 7.938176e-04 1.982957e-01 0.515965378 7 65975012 65975071 60 - 1.309 1.218 -0.320
ENSG00000169919 E026 8.3632251 3.597022e-02 5.370118e-01 0.803149047 7 65975072 65975851 780 - 0.916 0.987 0.266
ENSG00000169919 E027 3.1250077 5.491736e-02 5.838653e-01 0.829033422 7 65975852 65976014 163 - 0.557 0.635 0.347
ENSG00000169919 E028 62.2999329 2.680311e-04 1.624918e-01 0.466506561 7 65976015 65976202 188 - 1.822 1.768 -0.184
ENSG00000169919 E029 0.6221599 1.792165e-02 9.354715e-01   7 65979386 65979398 13 - 0.198 0.210 0.102
ENSG00000169919 E030 32.8222742 1.531329e-03 1.962099e-01 0.513040714 7 65979399 65979477 79 - 1.560 1.489 -0.244
ENSG00000169919 E031 37.5797404 1.282275e-02 2.093000e-01 0.530074953 7 65979478 65979541 64 - 1.627 1.538 -0.303
ENSG00000169919 E032 43.9958251 8.323575e-03 3.585399e-02 0.205267843 7 65979727 65979833 107 - 1.713 1.590 -0.418
ENSG00000169919 E033 35.5400551 4.188243e-04 5.465466e-01 0.808975319 7 65979834 65979911 78 - 1.570 1.538 -0.109
ENSG00000169919 E034 60.8110138 9.711425e-04 1.733458e-01 0.482727942 7 65980224 65980409 186 - 1.813 1.757 -0.189
ENSG00000169919 E035 0.2449549 1.610871e-02 7.972817e-01   7 65980410 65980411 2 - 0.110 0.082 -0.483
ENSG00000169919 E036 1.6834683 1.005772e-02 9.638418e-02 0.357732693 7 65980694 65980829 136 - 0.557 0.309 -1.331
ENSG00000169919 E037 0.3774055 1.651458e-02 8.098475e-01   7 65981851 65981973 123 - 0.110 0.151 0.517
ENSG00000169919 E038 49.9688794 2.997082e-04 1.435018e-02 0.117302324 7 65981974 65982241 268 - 1.757 1.652 -0.355

Help

Please Click HERE to learn more details about the results from DEXseq.