ENSG00000171552

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000376062 ENSG00000171552 No_inf pgwt_inf BCL2L1 protein_coding protein_coding 24.55027 26.80153 22.55399 1.058037 0.3656875 -0.2488316 2.118564 4.5587600 0.2123812 3.546615 0.2123812 -4.360696 0.07870000 0.159000 0.009150 -0.149850 9.928472e-01 2.207957e-06 FALSE TRUE
ENST00000420488 ENSG00000171552 No_inf pgwt_inf BCL2L1 protein_coding protein_coding 24.55027 26.80153 22.55399 1.058037 0.3656875 -0.2488316 4.235780 12.7073395 0.0000000 4.905902 0.0000000 -10.312581 0.16285833 0.488575 0.000000 -0.488575 1.923817e-01 2.207957e-06 FALSE TRUE
ENST00000439267 ENSG00000171552 No_inf pgwt_inf BCL2L1 protein_coding protein_coding 24.55027 26.80153 22.55399 1.058037 0.3656875 -0.2488316 6.777551 0.0000000 13.8117296 0.000000 2.4885411 10.432722 0.29220000 0.000000 0.609600 0.609600 2.207957e-06 2.207957e-06 FALSE TRUE
ENST00000676582 ENSG00000171552 No_inf pgwt_inf BCL2L1 protein_coding protein_coding 24.55027 26.80153 22.55399 1.058037 0.3656875 -0.2488316 1.814250 0.4538305 1.7066212 0.267707 0.7323862 1.887902 0.07620833 0.016550 0.077200 0.060650 9.928472e-01 2.207957e-06 FALSE TRUE
ENST00000676942 ENSG00000171552 No_inf pgwt_inf BCL2L1 protein_coding protein_coding 24.55027 26.80153 22.55399 1.058037 0.3656875 -0.2488316 1.646692 2.1876809 0.0000000 2.187681 0.0000000 -7.779838 0.06615833 0.088375 0.000000 -0.088375 9.932366e-01 2.207957e-06 FALSE TRUE
ENST00000678563 ENSG00000171552 No_inf pgwt_inf BCL2L1 protein_coding protein_coding 24.55027 26.80153 22.55399 1.058037 0.3656875 -0.2488316 3.261193 0.3302430 3.6511081 0.330243 1.5015695 3.427643 0.13842500 0.011125 0.163925 0.152800 2.679066e-01 2.207957e-06 FALSE TRUE
MSTRG.18119.13 ENSG00000171552 No_inf pgwt_inf BCL2L1 protein_coding   24.55027 26.80153 22.55399 1.058037 0.3656875 -0.2488316 1.577221 3.7528786 0.9787854 2.418810 0.5794093 -1.928107 0.05801667 0.130725 0.043325 -0.087400 1.000000e+00 2.207957e-06 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000171552 E001 0.0000000       20 31664452 31664457 6 -      
ENSG00000171552 E002 0.5245371 0.0157200969 0.075280994   20 31664458 31664462 5 - 0.000 0.273 11.706
ENSG00000171552 E003 0.5245371 0.0157200969 0.075280994   20 31664463 31664463 1 - 0.000 0.273 13.390
ENSG00000171552 E004 7.0266269 0.0861113177 0.277936587 0.6059327 20 31664464 31664512 49 - 0.793 0.959 0.638
ENSG00000171552 E005 13.4406942 0.0010620602 0.341431481 0.6633690 20 31664513 31664574 62 - 1.106 1.183 0.273
ENSG00000171552 E006 20.8363915 0.0006893279 0.586122035 0.8302614 20 31664575 31664644 70 - 1.311 1.347 0.127
ENSG00000171552 E007 87.9572455 0.0002010783 0.608109866 0.8416446 20 31664645 31665258 614 - 1.949 1.937 -0.039
ENSG00000171552 E008 109.3066846 0.0001676202 0.657889088 0.8664254 20 31665259 31665948 690 - 2.028 2.041 0.041
ENSG00000171552 E009 24.8396407 0.0029448343 0.238355364 0.5640153 20 31665949 31666086 138 - 1.445 1.376 -0.237
ENSG00000171552 E010 1.3934714 0.0295088107 0.258765419 0.5863447 20 31666991 31667147 157 - 0.260 0.440 1.092
ENSG00000171552 E011 0.2630299 0.2709326018 0.394015263   20 31684367 31684588 222 - 0.000 0.158 11.815
ENSG00000171552 E012 0.3431399 0.0289139987 0.067304829   20 31689344 31689374 31 - 0.260 0.000 -14.248
ENSG00000171552 E013 0.0000000       20 31719345 31719417 73 -      
ENSG00000171552 E014 0.0000000       20 31721655 31721843 189 -      
ENSG00000171552 E015 0.0000000       20 31721844 31722330 487 -      
ENSG00000171552 E016 0.0000000       20 31722331 31722348 18 -      
ENSG00000171552 E017 0.0000000       20 31722349 31722443 95 -      
ENSG00000171552 E018 0.0000000       20 31722444 31722476 33 -      
ENSG00000171552 E019 0.0000000       20 31722477 31722597 121 -      
ENSG00000171552 E020 0.0000000       20 31722618 31723529 912 -      
ENSG00000171552 E021 1.0430431 0.0163439902 0.005667076 0.0631889 20 31723735 31723847 113 - 0.504 0.086 -3.323
ENSG00000171552 E022 1.1747049 0.0143379568 0.022532703 0.1554745 20 31723848 31723863 16 - 0.504 0.158 -2.323
ENSG00000171552 E023 2.1921924 0.0331234304 0.370159265 0.6886984 20 31723864 31723989 126 - 0.573 0.440 -0.645

Help

Please Click HERE to learn more details about the results from DEXseq.