ENSG00000172469

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000358812 ENSG00000172469 No_inf pgwt_inf MANEA protein_coding protein_coding 10.7437 8.240297 10.02326 0.2648316 0.3514643 0.2822728 7.490864 4.209312 8.582947 0.6471801 0.3446008 1.026145 0.689750 0.512050 0.85605 0.344000 3.452631e-01 6.334414e-05 FALSE TRUE
ENST00000684164 ENSG00000172469 No_inf pgwt_inf MANEA protein_coding protein_coding_CDS_not_defined 10.7437 8.240297 10.02326 0.2648316 0.3514643 0.2822728 2.387608 3.382262 0.000000 0.5284564 0.0000000 -8.406104 0.223525 0.408375 0.00000 -0.408375 6.334414e-05 6.334414e-05 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000172469 E001 0.0000000       6 95577485 95577515 31 +      
ENSG00000172469 E002 0.1311489 0.0122525830 4.130451e-01   6 95577516 95577528 13 + 0.000 0.107 10.532
ENSG00000172469 E003 0.1311489 0.0122525830 4.130451e-01   6 95577529 95577534 6 + 0.000 0.107 12.033
ENSG00000172469 E004 0.7353803 0.0146307483 7.513854e-01 9.108200e-01 6 95577535 95577552 18 + 0.216 0.264 0.372
ENSG00000172469 E005 2.6649203 0.0056201975 8.053396e-01 9.334351e-01 6 95577553 95577638 86 + 0.580 0.545 -0.159
ENSG00000172469 E006 0.0000000       6 95577772 95577790 19 +      
ENSG00000172469 E007 0.1139502 0.0111138742 6.960098e-01   6 95577791 95577864 74 + 0.085 0.000 -12.563
ENSG00000172469 E008 0.4558815 0.0160247810 8.031391e-02   6 95577865 95578307 443 + 0.270 0.000 -14.352
ENSG00000172469 E009 0.0000000       6 95578308 95578311 4 +      
ENSG00000172469 E010 21.2574573 0.0006956272 3.333159e-04 7.673203e-03 6 95586402 95586983 582 + 1.439 1.213 -0.789
ENSG00000172469 E011 0.8669763 0.0140470294 4.747826e-01 7.644481e-01 6 95586984 95588221 1238 + 0.216 0.325 0.787
ENSG00000172469 E012 0.0000000       6 95588222 95588261 40 +      
ENSG00000172469 E013 1.1592156 0.0117040536 2.125972e-02 1.495618e-01 6 95588262 95589646 1385 + 0.468 0.107 -2.798
ENSG00000172469 E014 0.3600626 0.0168292365 7.572064e-01   6 95590000 95590173 174 + 0.155 0.107 -0.628
ENSG00000172469 E015 0.1311489 0.0122525830 4.130451e-01   6 95592564 95592646 83 + 0.000 0.107 12.033
ENSG00000172469 E016 6.6989727 0.0020255520 8.035211e-02 3.238870e-01 6 95596737 95596846 110 + 0.963 0.779 -0.706
ENSG00000172469 E017 1.0437783 0.0112919585 3.568465e-02 2.045961e-01 6 95596847 95597913 1067 + 0.435 0.107 -2.628
ENSG00000172469 E018 0.1316618 0.0122411088 4.131085e-01   6 95601206 95601278 73 + 0.000 0.107 12.033
ENSG00000172469 E019 1.3412718 0.0098780560 8.989321e-01 9.697360e-01 6 95603485 95604826 1342 + 0.360 0.379 0.109
ENSG00000172469 E020 4.9808976 0.0035183542 2.058577e-02 1.467761e-01 6 95604827 95604903 77 + 0.885 0.609 -1.123
ENSG00000172469 E021 178.7453539 0.0001204763 5.054293e-07 3.066425e-05 6 95605748 95609470 3723 + 2.230 2.279 0.162

Help

Please Click HERE to learn more details about the results from DEXseq.