ENSG00000173214

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000368847 ENSG00000173214 No_inf pgwt_inf MFSD4B protein_coding protein_coding 9.879849 7.435549 9.566675 1.496534 0.4194439 0.3631466 0.4810579 0.4685859 0.1402082 0.2799244 0.1402082 -1.67181438 0.05660833 0.077175 0.013500 -0.063675 0.992847247 0.00887513 FALSE TRUE
ENST00000671876 ENSG00000173214 No_inf pgwt_inf MFSD4B protein_coding protein_coding 9.879849 7.435549 9.566675 1.496534 0.4194439 0.3631466 2.5627661 2.4727496 2.6431296 0.1262453 0.1600978 0.09575636 0.29313333 0.369725 0.280300 -0.089425 0.992847247 0.00887513 FALSE TRUE
ENST00000671883 ENSG00000173214 No_inf pgwt_inf MFSD4B protein_coding nonsense_mediated_decay 9.879849 7.435549 9.566675 1.496534 0.4194439 0.3631466 1.2595559 1.0814822 0.8610869 0.3966943 0.3442729 -0.32540004 0.13550833 0.135175 0.088725 -0.046450 0.992847247 0.00887513 TRUE TRUE
ENST00000672303 ENSG00000173214 No_inf pgwt_inf MFSD4B protein_coding protein_coding 9.879849 7.435549 9.566675 1.496534 0.4194439 0.3631466 0.6919015 0.0000000 2.0757045 0.0000000 0.2764042 7.70439100 0.07381667 0.000000 0.221450 0.221450 0.008903234 0.00887513 FALSE TRUE
ENST00000672494 ENSG00000173214 No_inf pgwt_inf MFSD4B protein_coding protein_coding_CDS_not_defined 9.879849 7.435549 9.566675 1.496534 0.4194439 0.3631466 2.2327153 2.3284183 0.4002661 1.4872969 0.4002661 -2.51090100 0.17975000 0.231425 0.038550 -0.192875 0.992847247 0.00887513   FALSE
ENST00000672554 ENSG00000173214 No_inf pgwt_inf MFSD4B protein_coding protein_coding 9.879849 7.435549 9.566675 1.496534 0.4194439 0.3631466 1.3013771 0.0000000 1.9886007 0.0000000 0.2213781 7.64284645 0.11523333 0.000000 0.207750 0.207750 0.008875130 0.00887513 FALSE TRUE
ENST00000672750 ENSG00000173214 No_inf pgwt_inf MFSD4B protein_coding nonsense_mediated_decay 9.879849 7.435549 9.566675 1.496534 0.4194439 0.3631466 0.2681597 0.3131073 0.0000000 0.3131073 0.0000000 -5.01394126 0.03075000 0.062175 0.000000 -0.062175 0.992847247 0.00887513 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000173214 E001 0.0000000       6 111259327 111259338 12 +      
ENSG00000173214 E002 0.0000000       6 111259339 111259340 2 +      
ENSG00000173214 E003 0.4561570 0.0159497965 7.023162e-02   6 111259341 111259387 47 + 0.275 0.000 -11.601
ENSG00000173214 E004 2.7109232 0.0051747267 2.050578e-02 0.1464706744 6 111259388 111259496 109 + 0.698 0.372 -1.558
ENSG00000173214 E005 2.7107284 0.0053945020 2.054674e-02 0.1466261145 6 111259497 111259550 54 + 0.698 0.372 -1.558
ENSG00000173214 E006 1.9916871 0.0110379293 1.866230e-02 0.1382661960 6 111259551 111259612 62 + 0.613 0.258 -1.932
ENSG00000173214 E007 1.6501250 0.0253173780 7.412145e-02 0.3092390856 6 111259613 111259623 11 + 0.536 0.258 -1.584
ENSG00000173214 E008 3.4652027 0.0163903354 1.398648e-01 0.4328654486 6 111259624 111259727 104 + 0.735 0.536 -0.862
ENSG00000173214 E009 7.7334672 0.0021459605 3.314965e-01 0.6552415860 6 111262257 111262425 169 + 0.984 0.890 -0.351
ENSG00000173214 E010 5.9152034 0.0024557271 3.734768e-01 0.6912319429 6 111263830 111263946 117 + 0.883 0.788 -0.369
ENSG00000173214 E011 0.0000000       6 111265384 111265437 54 +      
ENSG00000173214 E012 56.9335488 0.0002552913 2.368368e-05 0.0008842564 6 111265876 111267658 1783 + 1.830 1.677 -0.517
ENSG00000173214 E013 2.2882968 0.0061047601 4.709129e-01 0.7617894229 6 111267659 111267837 179 + 0.563 0.462 -0.487
ENSG00000173214 E014 30.5479500 0.0005265574 2.031329e-01 0.5223304536 6 111267838 111269154 1317 + 1.528 1.465 -0.219
ENSG00000173214 E015 0.8679067 0.2130913656 6.226183e-01 0.8487858501 6 111269155 111269169 15 + 0.221 0.319 0.705
ENSG00000173214 E016 50.2995949 0.0003755068 2.700954e-04 0.0065471614 6 111269170 111272945 3776 + 1.634 1.778 0.489
ENSG00000173214 E017 5.7584296 0.0025527467 5.996021e-01 0.8374017223 6 111272946 111273329 384 + 0.800 0.859 0.229
ENSG00000173214 E018 2.6849474 0.0092786349 9.741146e-01 0.9954881189 6 111273330 111273380 51 + 0.563 0.569 0.027
ENSG00000173214 E019 2.1130279 0.0076712065 2.627094e-01 0.5907150796 6 111273381 111273401 21 + 0.406 0.569 0.805
ENSG00000173214 E020 1.4912318 0.0114180050 3.652830e-01 0.6841591199 6 111273402 111273422 21 + 0.324 0.462 0.776
ENSG00000173214 E021 0.8851100 0.0134037838 1.627518e-01 0.4669931942 6 111273423 111273429 7 + 0.159 0.372 1.612
ENSG00000173214 E022 19.4876723 0.0008629074 3.071149e-01 0.6334692601 6 111273430 111274526 1097 + 1.277 1.345 0.236
ENSG00000173214 E023 15.1536661 0.0224902363 7.790043e-01 0.9234150403 6 111274527 111275561 1035 + 1.193 1.223 0.104
ENSG00000173214 E024 17.2275075 0.0009893915 6.780459e-01 0.8760103162 6 111275562 111276716 1155 + 1.246 1.276 0.106
ENSG00000173214 E025 9.6292762 0.0370097001 2.349889e-01 0.5600429275 6 111276717 111277207 491 + 0.953 1.092 0.513
ENSG00000173214 E026 3.1272351 0.0048184709 5.998693e-02 0.2753537575 6 111277208 111277325 118 + 0.476 0.727 1.120
ENSG00000173214 E027 15.1593362 0.0009717408 4.260526e-01 0.7305134453 6 111277326 111277977 652 + 1.235 1.178 -0.199
ENSG00000173214 E028 2.1089398 0.1486002595 4.241356e-01 0.7292049677 6 111277978 111277999 22 + 0.406 0.569 0.804
ENSG00000173214 E029 6.6773437 0.0020176517 1.243187e-01 0.4084405655 6 111278000 111278158 159 + 0.800 0.960 0.612
ENSG00000173214 E030 7.0182538 0.0362271712 3.396787e-01 0.6619758711 6 111278159 111278412 254 + 0.844 0.960 0.443
ENSG00000173214 E031 8.7174367 0.0016726141 3.429230e-01 0.6643111255 6 111278413 111278773 361 + 0.942 1.031 0.331
ENSG00000173214 E032 7.8782447 0.0108525234 5.955091e-01 0.8353113943 6 111278774 111280005 1232 + 0.974 0.920 -0.203
ENSG00000173214 E033 0.7710147 0.2785110604 1.461487e-01 0.4421022001 6 111295450 111295703 254 + 0.087 0.372 2.613
ENSG00000173214 E034 0.2625250 0.0160849293 1.818870e-01   6 111295704 111295775 72 + 0.000 0.188 12.750
ENSG00000173214 E035 0.1308632 0.0122176331 4.411002e-01   6 111295776 111295811 36 + 0.000 0.104 11.833
ENSG00000173214 E036 0.1141751 0.0111962306 6.534139e-01   6 111326114 111326326 213 + 0.087 0.000 -12.374
ENSG00000173214 E037 1.8825804 0.0075008241 9.604409e-02 0.3568696250 6 111354615 111355782 1168 + 0.324 0.569 1.290
ENSG00000173214 E038 0.5073330 0.0157823416 2.336148e-01   6 111355783 111355850 68 + 0.087 0.258 1.875
ENSG00000173214 E039 1.6213574 0.0087110470 2.394292e-01 0.5651802042 6 111404380 111405287 908 + 0.324 0.501 0.968
ENSG00000173214 E040 0.0000000       6 111440703 111440765 63 +      
ENSG00000173214 E041 0.1145948 0.0112053969 6.534639e-01   6 111444933 111445354 422 + 0.087 0.000 -12.374

Help

Please Click HERE to learn more details about the results from DEXseq.