ENSG00000174165

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000310442 ENSG00000174165 No_inf pgwt_inf ZDHHC24 protein_coding protein_coding 12.74504 9.989399 14.29213 0.4822783 0.5413906 0.5163167 6.612059 5.80388093 7.231232 0.27308750 0.4401493 0.31673371 0.52821667 0.582925 0.511225 -0.071700 0.992847247 0.008493407 FALSE TRUE
ENST00000525925 ENSG00000174165 No_inf pgwt_inf ZDHHC24 protein_coding protein_coding_CDS_not_defined 12.74504 9.989399 14.29213 0.4822783 0.5413906 0.5163167 3.098047 0.09242711 5.480196 0.09242711 1.2984842 5.74418811 0.21460833 0.008725 0.374250 0.365525 0.008493407 0.008493407 FALSE FALSE
ENST00000534073 ENSG00000174165 No_inf pgwt_inf ZDHHC24 protein_coding nonsense_mediated_decay 12.74504 9.989399 14.29213 0.4822783 0.5413906 0.5163167 1.859375 3.49685251 1.264737 0.49087016 0.5434681 -1.45997712 0.16668333 0.351175 0.092600 -0.258575 0.597605125 0.008493407 TRUE TRUE
MSTRG.5009.2 ENSG00000174165 No_inf pgwt_inf ZDHHC24 protein_coding   12.74504 9.989399 14.29213 0.4822783 0.5413906 0.5163167 1.026665 0.29732268 0.315965 0.29732268 0.3159650 0.08496283 0.07773333 0.028375 0.021900 -0.006475 1.000000000 0.008493407 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000174165 E001 0.7692036 0.0152697267 4.221909e-02 0.2255508166 11 66520637 66520718 82 - 0.083 0.386 2.770
ENSG00000174165 E002 0.6552534 0.0225186678 8.604940e-03 0.0839863633 11 66520719 66521081 363 - 0.000 0.386 12.790
ENSG00000174165 E003 0.0000000       11 66521082 66521466 385 -      
ENSG00000174165 E004 1.0159708 0.0118725983 6.447734e-02 0.2864744895 11 66524155 66524276 122 - 0.152 0.434 2.033
ENSG00000174165 E005 0.0000000       11 66526936 66527006 71 -      
ENSG00000174165 E006 0.7874281 0.0149649142 3.322632e-03 0.0436381165 11 66529312 66529488 177 - 0.000 0.434 13.083
ENSG00000174165 E007 136.5437641 0.0002290053 2.939346e-06 0.0001458300 11 66535626 66539824 4199 - 2.102 2.175 0.247
ENSG00000174165 E008 0.8509352 0.0128767369 9.874281e-01 0.9998524659 11 66542484 66542828 345 - 0.264 0.269 0.033
ENSG00000174165 E009 36.8530915 0.0030439751 3.460996e-03 0.0449328475 11 66543704 66543981 278 - 1.635 1.496 -0.475
ENSG00000174165 E010 24.9566988 0.0011599726 3.132620e-06 0.0001541226 11 66545723 66546235 513 - 1.517 1.245 -0.941

Help

Please Click HERE to learn more details about the results from DEXseq.