ENSG00000174437

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000313432 ENSG00000174437 No_inf pgwt_inf ATP2A2 protein_coding retained_intron 155.6226 101.0543 193.7989 2.827311 1.670506 0.9393614 8.933853 18.669856 4.803818 0.6394014 0.4137194 -1.956230 0.07641667 0.18515 0.024750 -0.160400 0.0008067702 0.0008067702 FALSE TRUE
ENST00000539276 ENSG00000174437 No_inf pgwt_inf ATP2A2 protein_coding protein_coding 155.6226 101.0543 193.7989 2.827311 1.670506 0.9393614 13.061657 5.637914 15.643248 0.2422384 0.2740478 1.470672 0.08023333 0.05580 0.080700 0.024900 0.9928472467 0.0008067702 FALSE TRUE
ENST00000548169 ENSG00000174437 No_inf pgwt_inf ATP2A2 protein_coding protein_coding 155.6226 101.0543 193.7989 2.827311 1.670506 0.9393614 86.938679 42.443896 120.282002 0.8893664 3.6751097 1.502572 0.53705833 0.42095 0.620325 0.199375 0.7812136503 0.0008067702 FALSE TRUE
MSTRG.7164.5 ENSG00000174437 No_inf pgwt_inf ATP2A2 protein_coding   155.6226 101.0543 193.7989 2.827311 1.670506 0.9393614 41.191554 27.008959 46.907305 0.3031046 2.4932853 0.796148 0.26640000 0.26795 0.242375 -0.025575 0.9983511466 0.0008067702 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000174437 E001 0.4909258 1.587072e-02 5.181483e-01   12 110280756 110280964 209 + 0.131 0.226 0.963
ENSG00000174437 E002 0.8152897 1.348340e-02 2.434063e-01 5.695569e-01 12 110281116 110281246 131 + 0.312 0.128 -1.622
ENSG00000174437 E003 4.2113857 2.985802e-02 3.300100e-02 1.948278e-01 12 110281247 110281296 50 + 0.797 0.484 -1.359
ENSG00000174437 E004 15.9549180 8.248573e-04 8.703221e-03 8.469646e-02 12 110281297 110281622 326 + 1.280 1.077 -0.723
ENSG00000174437 E005 60.9360722 4.586927e-04 5.181817e-03 5.967286e-02 12 110281623 110281907 285 + 1.815 1.704 -0.377
ENSG00000174437 E006 0.0000000       12 110281908 110281918 11 +      
ENSG00000174437 E007 23.6740337 2.297551e-03 4.447576e-03 5.358693e-02 12 110282604 110282621 18 + 1.439 1.249 -0.660
ENSG00000174437 E008 43.0420922 5.265120e-04 8.256239e-03 8.187758e-02 12 110282713 110282795 83 + 1.672 1.546 -0.426
ENSG00000174437 E009 33.1116993 4.087154e-04 6.220412e-03 6.766737e-02 12 110292020 110292048 29 + 1.568 1.420 -0.507
ENSG00000174437 E010 53.9077038 2.610953e-04 9.681451e-03 9.093466e-02 12 110292049 110292124 76 + 1.762 1.654 -0.365
ENSG00000174437 E011 0.2456901 1.623780e-02 6.100304e-01   12 110295991 110296314 324 + 0.070 0.128 0.963
ENSG00000174437 E012 101.3340977 1.399755e-04 1.160094e-05 4.841568e-04 12 110296599 110296737 139 + 2.041 1.905 -0.457
ENSG00000174437 E013 79.0834772 1.712751e-03 1.447845e-06 7.858924e-05 12 110322992 110323072 81 + 1.950 1.759 -0.645
ENSG00000174437 E014 2.1914866 1.129463e-01 4.426191e-01 7.425616e-01 12 110325801 110326389 589 + 0.440 0.572 0.642
ENSG00000174437 E015 65.7471345 3.047718e-03 8.051247e-02 3.242857e-01 12 110326390 110326475 86 + 1.836 1.762 -0.250
ENSG00000174437 E016 103.3124873 1.394668e-04 3.773621e-02 2.112480e-01 12 110327553 110327686 134 + 2.025 1.965 -0.200
ENSG00000174437 E017 200.9069293 1.971927e-03 1.767886e-03 2.774166e-02 12 110327687 110328017 331 + 2.320 2.235 -0.282
ENSG00000174437 E018 3.9785757 9.573716e-02 2.755326e-02 1.753668e-01 12 110329399 110331971 2573 + 0.516 0.875 1.512
ENSG00000174437 E019 2.0953969 7.249243e-03 1.188211e-01 3.988931e-01 12 110331972 110332596 625 + 0.381 0.610 1.133
ENSG00000174437 E020 65.2520338 2.885387e-03 6.772163e-02 2.947021e-01 12 110332597 110332685 89 + 1.834 1.756 -0.260
ENSG00000174437 E021 78.5704804 1.871902e-04 2.356035e-03 3.415414e-02 12 110333181 110333283 103 + 1.922 1.817 -0.354
ENSG00000174437 E022 109.4404089 4.553962e-03 5.504891e-05 1.806135e-03 12 110334012 110334143 132 + 2.083 1.918 -0.554
ENSG00000174437 E023 0.0000000       12 110334144 110334291 148 +      
ENSG00000174437 E024 90.0263912 3.093069e-04 3.208608e-04 7.454361e-03 12 110339281 110339403 123 + 1.985 1.866 -0.399
ENSG00000174437 E025 150.2224822 1.410327e-04 1.480397e-04 4.034311e-03 12 110339503 110339721 219 + 2.197 2.103 -0.316
ENSG00000174437 E026 275.5965653 6.822448e-05 6.314979e-09 5.615359e-07 12 110340659 110340994 336 + 2.463 2.357 -0.354
ENSG00000174437 E027 227.3352217 7.906344e-05 1.138626e-03 1.979859e-02 12 110342228 110342448 221 + 2.366 2.303 -0.210
ENSG00000174437 E028 87.2329260 1.806473e-04 2.836478e-02 1.783263e-01 12 110343232 110343255 24 + 1.955 1.886 -0.234
ENSG00000174437 E029 206.9457291 8.690689e-05 1.571999e-04 4.229657e-03 12 110343256 110343434 179 + 2.330 2.252 -0.261
ENSG00000174437 E030 147.8464510 1.184635e-03 6.242270e-02 2.813527e-01 12 110344886 110344971 86 + 2.176 2.126 -0.167
ENSG00000174437 E031 1.5693093 9.210652e-03 7.511375e-01 9.108042e-01 12 110344972 110345247 276 + 0.381 0.433 0.285
ENSG00000174437 E032 192.4644185 3.717174e-03 9.254027e-03 8.838778e-02 12 110345249 110345382 134 + 2.301 2.218 -0.277
ENSG00000174437 E033 19.6926074 2.958419e-03 4.313716e-08 3.314008e-06 12 110345437 110346000 564 + 1.117 1.502 1.347
ENSG00000174437 E034 192.3398386 8.658296e-05 3.052856e-05 1.099484e-03 12 110346001 110346118 118 + 2.303 2.212 -0.303
ENSG00000174437 E035 201.4580963 9.184634e-05 9.938630e-03 9.228653e-02 12 110346201 110346321 121 + 2.310 2.258 -0.174
ENSG00000174437 E036 957.4563175 5.330544e-05 1.013856e-01 3.669684e-01 12 110346322 110347392 1071 + 2.959 2.980 0.070
ENSG00000174437 E037 10.6568286 1.270663e-03 2.030556e-05 7.805511e-04 12 110347393 110347453 61 + 0.874 1.249 1.368
ENSG00000174437 E038 44.1747331 3.379220e-04 1.049145e-09 1.066952e-07 12 110347454 110347791 338 + 1.513 1.796 0.963
ENSG00000174437 E039 332.8316847 3.376556e-04 1.577348e-106 1.196216e-102 12 110347792 110350291 2500 + 2.319 2.712 1.310
ENSG00000174437 E040 209.6510565 1.853667e-03 5.798658e-52 1.465846e-48 12 110350292 110351093 802 + 2.105 2.522 1.395

Help

Please Click HERE to learn more details about the results from DEXseq.