ENSG00000175931

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000319380 ENSG00000175931 No_inf pgwt_inf UBE2O protein_coding protein_coding 10.86601 11.39361 10.8837 0.4363071 0.7765774 -0.0659965 3.6238015 3.026522 3.5352752 0.9078133 0.4805595 0.2234777 0.34022500 0.265400 0.325375 0.059975 0.99284725 0.04533611 FALSE TRUE
ENST00000586505 ENSG00000175931 No_inf pgwt_inf UBE2O protein_coding retained_intron 10.86601 11.39361 10.8837 0.4363071 0.7765774 -0.0659965 0.7212907 1.394268 0.0000000 0.3259664 0.0000000 -7.1336742 0.06392500 0.124175 0.000000 -0.124175 0.04533611 0.04533611   FALSE
ENST00000587127 ENSG00000175931 No_inf pgwt_inf UBE2O protein_coding protein_coding 10.86601 11.39361 10.8837 0.4363071 0.7765774 -0.0659965 0.3226591 0.000000 0.9679772 0.0000000 0.9679772 6.6117289 0.02948333 0.000000 0.088450 0.088450 0.99284725 0.04533611 FALSE TRUE
MSTRG.13324.2 ENSG00000175931 No_inf pgwt_inf UBE2O protein_coding   10.86601 11.39361 10.8837 0.4363071 0.7765774 -0.0659965 1.6664201 1.177619 0.6320818 0.6899594 0.6320818 -0.8872435 0.15390833 0.098500 0.059400 -0.039100 0.99284725 0.04533611 FALSE TRUE
MSTRG.13324.3 ENSG00000175931 No_inf pgwt_inf UBE2O protein_coding   10.86601 11.39361 10.8837 0.4363071 0.7765774 -0.0659965 1.4154453 1.619752 2.4218347 0.9533853 0.8389523 0.5773928 0.13149167 0.150875 0.221550 0.070675 0.99284725 0.04533611 FALSE TRUE
MSTRG.13324.4 ENSG00000175931 No_inf pgwt_inf UBE2O protein_coding   10.86601 11.39361 10.8837 0.4363071 0.7765774 -0.0659965 2.7383085 3.847360 2.9878647 0.7769718 1.0465772 -0.3636786 0.24726667 0.332700 0.276625 -0.056075 0.99284725 0.04533611 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000175931 E001 0.2456120 0.0164577618 0.96365401   17 76389456 76389457 2 - 0.092 0.098 0.094
ENSG00000175931 E002 0.5076241 0.0154713777 0.29224525   17 76389458 76389466 9 - 0.092 0.245 1.679
ENSG00000175931 E003 22.3742158 0.0077921334 0.11399441 0.39036944 17 76389467 76389796 330 - 1.305 1.420 0.398
ENSG00000175931 E004 127.6091341 0.0001564692 0.10317395 0.37012436 17 76389797 76391613 1817 - 2.089 2.126 0.124
ENSG00000175931 E005 1.5869018 0.1670105518 0.87062460 0.95925736 17 76391614 76391755 142 - 0.425 0.401 -0.129
ENSG00000175931 E006 5.9772948 0.0038255265 0.10360753 0.37086210 17 76391756 76391813 58 - 0.741 0.921 0.704
ENSG00000175931 E007 5.2562228 0.0027619658 0.04121231 0.22251797 17 76391910 76391945 36 - 0.658 0.894 0.942
ENSG00000175931 E008 10.6842598 0.0017408199 0.70343613 0.88887697 17 76391946 76392113 168 - 1.049 1.084 0.127
ENSG00000175931 E009 1.7167135 0.0101073656 0.91306433 0.97427053 17 76395358 76395724 367 - 0.425 0.443 0.094
ENSG00000175931 E010 8.1075957 0.0017549638 0.17477574 0.48485013 17 76395725 76395861 137 - 1.020 0.894 -0.473
ENSG00000175931 E011 0.3764698 0.0166023558 0.54960135   17 76395862 76396127 266 - 0.092 0.178 1.094
ENSG00000175931 E012 34.3581039 0.0004745756 0.03051797 0.18653736 17 76396128 76396821 694 - 1.598 1.496 -0.348
ENSG00000175931 E013 2.7966994 0.0293675016 0.62605084 0.85023739 17 76397799 76397807 9 - 0.611 0.548 -0.285
ENSG00000175931 E014 4.7776994 0.0030556743 0.98547010 0.99935667 17 76397808 76397888 81 - 0.759 0.764 0.020
ENSG00000175931 E015 0.2453240 0.0165709602 0.96538379   17 76397889 76397891 3 - 0.092 0.098 0.094
ENSG00000175931 E016 7.9335311 0.0609184732 0.81658789 0.93733266 17 76398255 76398383 129 - 0.968 0.934 -0.128
ENSG00000175931 E017 7.2460315 0.0560870207 0.80301642 0.93270619 17 76398472 76398584 113 - 0.896 0.934 0.143
ENSG00000175931 E018 5.2168182 0.0156518252 0.42096230 0.72690384 17 76398837 76398893 57 - 0.840 0.744 -0.380
ENSG00000175931 E019 7.0183972 0.0026992178 0.17890086 0.49116595 17 76398894 76398991 98 - 0.968 0.834 -0.512
ENSG00000175931 E020 0.3931610 0.0228774190 0.09383201   17 76399308 76399448 141 - 0.000 0.245 10.634
ENSG00000175931 E021 15.2117807 0.0008831771 0.30318101 0.63004191 17 76399449 76399788 340 - 1.245 1.173 -0.254
ENSG00000175931 E022 8.2706348 0.0018701021 0.01063254 0.09653477 17 76399789 76399921 133 - 1.076 0.834 -0.906
ENSG00000175931 E023 3.2528086 0.0056946219 0.23561248 0.56066674 17 76400147 76400221 75 - 0.701 0.548 -0.672
ENSG00000175931 E024 3.2517142 0.0621016810 0.32600208 0.65050920 17 76400222 76400297 76 - 0.701 0.548 -0.672
ENSG00000175931 E025 3.2697305 0.0044469718 0.41863653 0.72497467 17 76400441 76400550 110 - 0.681 0.578 -0.447
ENSG00000175931 E026 5.0094728 0.0704883390 0.78626689 0.92590747 17 76401011 76401154 144 - 0.793 0.764 -0.118
ENSG00000175931 E027 0.4746476 0.3823858310 0.56030508   17 76401155 76401186 32 - 0.233 0.098 -1.493
ENSG00000175931 E028 1.1653514 0.0107934349 0.01111907 0.09962641 17 76401731 76402063 333 - 0.092 0.480 3.094
ENSG00000175931 E029 2.3744552 0.0289247636 0.23325699 0.55873479 17 76402064 76402127 64 - 0.425 0.606 0.871
ENSG00000175931 E030 2.5053153 0.1521953203 0.32855801 0.65261415 17 76402602 76402659 58 - 0.425 0.632 0.987
ENSG00000175931 E031 2.4087152 0.0982791478 0.08061804 0.32451391 17 76402660 76402699 40 - 0.339 0.657 1.579
ENSG00000175931 E032 2.8304755 0.0509534383 0.80654227 0.93376241 17 76405206 76405250 45 - 0.557 0.606 0.219
ENSG00000175931 E033 2.6666395 0.0053266142 0.47689339 0.76556222 17 76405251 76405316 66 - 0.611 0.515 -0.437
ENSG00000175931 E034 3.1408772 0.0045968550 0.30597686 0.63268231 17 76405513 76405572 60 - 0.681 0.548 -0.584
ENSG00000175931 E035 6.3300878 0.0039256045 0.53766065 0.80355004 17 76452725 76453210 486 - 0.896 0.834 -0.241

Help

Please Click HERE to learn more details about the results from DEXseq.