ENSG00000176659

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000625080 ENSG00000176659 No_inf pgwt_inf LINC02910 lncRNA lncRNA 18.2886 9.893422 20.04394 0.793746 1.914853 1.017887 2.3034756 3.7887628 0.7404082 0.2812898 0.7404082 -2.3397821 0.18164167 0.384250 0.039925 -0.344325 0.09514694 0.02778307 FALSE FALSE
ENST00000647608 ENSG00000176659 No_inf pgwt_inf LINC02910 lncRNA lncRNA 18.2886 9.893422 20.04394 0.793746 1.914853 1.017887 7.1033674 3.1620665 8.3766737 0.3259773 1.0074783 1.4026757 0.38395833 0.327675 0.418600 0.090925 0.99284725 0.02778307   FALSE
ENST00000660831 ENSG00000176659 No_inf pgwt_inf LINC02910 lncRNA lncRNA 18.2886 9.893422 20.04394 0.793746 1.914853 1.017887 1.8912248 0.0000000 3.3715750 0.0000000 0.8082153 8.4015516 0.08310833 0.000000 0.173150 0.173150 0.02778307 0.02778307 FALSE FALSE
ENST00000691246 ENSG00000176659 No_inf pgwt_inf LINC02910 lncRNA lncRNA 18.2886 9.893422 20.04394 0.793746 1.914853 1.017887 1.1728054 0.4431442 1.2520817 0.4431442 0.7480944 1.4777631 0.06100000 0.037250 0.060800 0.023550 0.99284725 0.02778307   FALSE
ENST00000701068 ENSG00000176659 No_inf pgwt_inf LINC02910 lncRNA lncRNA 18.2886 9.893422 20.04394 0.793746 1.914853 1.017887 0.8672976 0.6388502 0.3289161 0.3688412 0.3289161 -0.9369572 0.04828333 0.065750 0.013725 -0.052025 0.99284725 0.02778307   FALSE
MSTRG.18469.10 ENSG00000176659 No_inf pgwt_inf LINC02910 lncRNA   18.2886 9.893422 20.04394 0.793746 1.914853 1.017887 2.3468525 0.7265865 4.4817198 0.7265865 0.8144396 2.6083410 0.11715000 0.061050 0.220800 0.159750 0.49656580 0.02778307   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000176659 E001 0.0000000       20 60055853 60055869 17 +      
ENSG00000176659 E002 0.0000000       20 60055870 60055904 35 +      
ENSG00000176659 E003 0.0000000       20 60055905 60055918 14 +      
ENSG00000176659 E004 0.0000000       20 60055919 60055920 2 +      
ENSG00000176659 E005 0.0000000       20 60055921 60055924 4 +      
ENSG00000176659 E006 5.5915743 0.0221786158 6.919732e-02 0.298117901 20 60055925 60056008 84 + 0.905 0.678 -0.904
ENSG00000176659 E007 0.3763283 0.0171720649 3.907951e-01   20 60056009 60056306 298 + 0.082 0.198 1.483
ENSG00000176659 E008 13.6869807 0.0020453473 2.736477e-03 0.038118243 20 60057330 60057929 600 + 1.255 1.023 -0.830
ENSG00000176659 E009 0.2291896 0.2601955498 4.471956e-01   20 60058334 60058380 47 + 0.151 0.000 -9.488
ENSG00000176659 E010 1.4555840 0.0090988493 9.875756e-01 0.999852466 20 60058907 60058986 80 + 0.389 0.389 -0.002
ENSG00000176659 E011 2.5010840 0.0064814804 2.213942e-01 0.545253309 20 60066318 60066452 135 + 0.613 0.437 -0.838
ENSG00000176659 E012 11.9654712 0.0166055258 7.194645e-01 0.897034341 20 60067592 60068709 1118 + 1.128 1.090 -0.138
ENSG00000176659 E013 1.5188711 0.0094642219 4.282604e-02 0.227291917 20 60069059 60069178 120 + 0.516 0.198 -1.976
ENSG00000176659 E014 4.0458115 0.0303546618 4.637036e-01 0.756758012 20 60069833 60070043 211 + 0.655 0.751 0.396
ENSG00000176659 E015 51.6326385 0.0004069904 7.444204e-05 0.002320511 20 60070597 60072956 2360 + 1.668 1.774 0.360

Help

Please Click HERE to learn more details about the results from DEXseq.