ENSG00000177731

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000327031 ENSG00000177731 No_inf pgwt_inf FLII protein_coding protein_coding 63.79702 65.77702 67.63058 3.516059 6.225873 0.04008597 11.593334 9.484718 11.235181 2.128987 1.768912 0.2441098 0.18637500 0.148100 0.169375 0.021275 0.9952493694 0.0001658983 FALSE TRUE
ENST00000474265 ENSG00000177731 No_inf pgwt_inf FLII protein_coding retained_intron 63.79702 65.77702 67.63058 3.516059 6.225873 0.04008597 6.342266 5.416094 6.017992 3.130100 2.212287 0.1517635 0.09891667 0.079600 0.086475 0.006875 1.0000000000 0.0001658983 FALSE FALSE
ENST00000577402 ENSG00000177731 No_inf pgwt_inf FLII protein_coding retained_intron 63.79702 65.77702 67.63058 3.516059 6.225873 0.04008597 2.536892 4.887100 1.740593 2.037541 1.740593 -1.4840837 0.03604167 0.071450 0.020650 -0.050800 0.8411287589 0.0001658983 FALSE FALSE
ENST00000580453 ENSG00000177731 No_inf pgwt_inf FLII protein_coding retained_intron 63.79702 65.77702 67.63058 3.516059 6.225873 0.04008597 20.869997 18.889628 24.722544 1.238020 3.102429 0.3880528 0.32561667 0.289825 0.362500 0.072675 0.9928472467 0.0001658983 FALSE FALSE
ENST00000581858 ENSG00000177731 No_inf pgwt_inf FLII protein_coding nonsense_mediated_decay 63.79702 65.77702 67.63058 3.516059 6.225873 0.04008597 9.451399 11.605565 9.869604 1.816894 2.691652 -0.2335342 0.14555000 0.173475 0.145300 -0.028175 0.9928472467 0.0001658983   FALSE
MSTRG.12197.4 ENSG00000177731 No_inf pgwt_inf FLII protein_coding   63.79702 65.77702 67.63058 3.516059 6.225873 0.04008597 3.726294 0.000000 8.345577 0.000000 2.254026 9.7065957 0.06194167 0.000000 0.130150 0.130150 0.0001658983 0.0001658983 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000177731 E001 0.0000000       17 18244815 18244823 9 -      
ENSG00000177731 E002 0.0000000       17 18244824 18244834 11 -      
ENSG00000177731 E003 0.0000000       17 18244835 18244835 1 -      
ENSG00000177731 E004 0.0000000       17 18244836 18244840 5 -      
ENSG00000177731 E005 0.0000000       17 18244841 18244858 18 -      
ENSG00000177731 E006 6.6098092 0.0021247099 0.757595146 0.91391676 17 18244859 18244921 63 - 0.865 0.897 0.122
ENSG00000177731 E007 25.9659879 0.0006204915 0.779046352 0.92342372 17 18244922 18245058 137 - 1.439 1.422 -0.057
ENSG00000177731 E008 39.1760230 0.0006741508 0.978276964 0.99701047 17 18245059 18245228 170 - 1.603 1.604 0.004
ENSG00000177731 E009 12.5287312 0.0162912416 0.392165182 0.70571122 17 18245229 18245229 1 - 1.090 1.170 0.285
ENSG00000177731 E010 14.3260118 0.0191478708 0.635132025 0.85456585 17 18245230 18245237 8 - 1.163 1.207 0.155
ENSG00000177731 E011 15.6200066 0.0095963308 0.235457690 0.56054114 17 18245238 18245245 8 - 1.170 1.267 0.342
ENSG00000177731 E012 22.5904558 0.0163380850 0.081736758 0.32703031 17 18245246 18245272 27 - 1.296 1.439 0.497
ENSG00000177731 E013 0.5070504 0.0264499841 0.252163844   17 18245273 18245350 78 - 0.089 0.254 1.814
ENSG00000177731 E014 0.0000000       17 18245351 18245353 3 -      
ENSG00000177731 E015 28.2533459 0.0044554638 0.026183696 0.17059250 17 18245354 18245419 66 - 1.394 1.530 0.469
ENSG00000177731 E016 0.4917998 0.1129328896 0.887595815   17 18245420 18245554 135 - 0.162 0.185 0.229
ENSG00000177731 E017 33.6302128 0.0007194640 0.597443493 0.83636732 17 18245555 18245660 106 - 1.526 1.553 0.092
ENSG00000177731 E018 3.1443473 0.0053285168 0.029008567 0.18031406 17 18245661 18245743 83 - 0.449 0.741 1.316
ENSG00000177731 E019 31.4509196 0.0010585458 0.133990226 0.42417587 17 18245744 18245837 94 - 1.470 1.550 0.274
ENSG00000177731 E020 14.3015701 0.0044924984 0.843513823 0.94824079 17 18245838 18245850 13 - 1.177 1.192 0.056
ENSG00000177731 E021 3.0950414 0.0050169615 0.325235629 0.64968455 17 18245851 18245933 83 - 0.543 0.673 0.577
ENSG00000177731 E022 23.3699259 0.0043743917 0.144354020 0.43960930 17 18245934 18245989 56 - 1.431 1.336 -0.331
ENSG00000177731 E023 22.8734363 0.0009935769 0.110048956 0.38306071 17 18245990 18246062 73 - 1.424 1.325 -0.343
ENSG00000177731 E024 0.0000000       17 18246111 18246152 42 -      
ENSG00000177731 E025 0.0000000       17 18246153 18246161 9 -      
ENSG00000177731 E026 21.7647468 0.0006402510 0.509692562 0.78623640 17 18246162 18246222 61 - 1.377 1.336 -0.144
ENSG00000177731 E027 1.4912831 0.0217684686 0.406985423 0.71632997 17 18246223 18246307 85 - 0.329 0.456 0.714
ENSG00000177731 E028 50.2960578 0.0002890205 0.433472081 0.73607891 17 18246308 18246462 155 - 1.694 1.726 0.109
ENSG00000177731 E029 0.3764698 0.0166352360 0.489834999   17 18246545 18246593 49 - 0.089 0.185 1.229
ENSG00000177731 E030 66.8118970 0.0002538821 0.709087620 0.89168839 17 18246594 18246828 235 - 1.838 1.824 -0.046
ENSG00000177731 E031 25.7955214 0.0051277068 0.133544576 0.42342157 17 18246913 18247052 140 - 1.473 1.376 -0.334
ENSG00000177731 E032 0.2287699 0.0154148692 0.301414303   17 18247053 18247125 73 - 0.162 0.000 -11.845
ENSG00000177731 E033 6.8700729 0.0302786978 0.232845834 0.55840111 17 18247169 18247175 7 - 0.961 0.817 -0.549
ENSG00000177731 E034 28.1495429 0.0093502650 0.798670015 0.93075054 17 18247176 18247357 182 - 1.473 1.456 -0.059
ENSG00000177731 E035 0.2457437 0.0163285224 0.901618705   17 18247358 18247436 79 - 0.089 0.102 0.229
ENSG00000177731 E036 32.3002782 0.0029996439 0.601881678 0.83856692 17 18247657 18247848 192 - 1.508 1.536 0.098
ENSG00000177731 E037 22.5610722 0.0006152010 0.352481599 0.67267635 17 18247929 18248033 105 - 1.343 1.400 0.197
ENSG00000177731 E038 27.2490104 0.0004949033 0.491736453 0.77529912 17 18248550 18248721 172 - 1.470 1.431 -0.134
ENSG00000177731 E039 0.0000000       17 18248722 18248759 38 -      
ENSG00000177731 E040 15.6148489 0.0126865377 0.256815558 0.58453122 17 18248800 18248883 84 - 1.265 1.170 -0.338
ENSG00000177731 E041 17.8188149 0.0013822552 0.234612482 0.55980426 17 18249127 18249201 75 - 1.232 1.314 0.289
ENSG00000177731 E042 18.6360194 0.0094065793 0.466722355 0.75856764 17 18249326 18249408 83 - 1.265 1.320 0.191
ENSG00000177731 E043 25.4136204 0.0005756634 0.469329221 0.76058496 17 18250838 18251017 180 - 1.442 1.400 -0.146
ENSG00000177731 E044 0.7694285 0.0258633955 0.064747275 0.28713104 17 18251018 18251264 247 - 0.089 0.366 2.551
ENSG00000177731 E045 16.3144721 0.0214346550 0.232346246 0.55796050 17 18251265 18251386 122 - 1.291 1.177 -0.401
ENSG00000177731 E046 17.8538617 0.0009301035 0.045415143 0.23421942 17 18251387 18251477 91 - 1.339 1.200 -0.487
ENSG00000177731 E047 17.2191117 0.0062556588 0.325706628 0.65004181 17 18251680 18251813 134 - 1.296 1.221 -0.263
ENSG00000177731 E048 2.7318955 0.0135509903 0.235556701 0.56066587 17 18251814 18251816 3 - 0.482 0.648 0.759
ENSG00000177731 E049 9.4032402 0.0154761038 0.920490573 0.97709287 17 18251999 18252055 57 - 1.012 1.023 0.041
ENSG00000177731 E050 9.8339501 0.0014766681 0.354836961 0.67486654 17 18252056 18252114 59 - 0.992 1.074 0.301
ENSG00000177731 E051 7.4772076 0.0026713883 0.628480204 0.85113210 17 18252115 18252146 32 - 0.904 0.952 0.182
ENSG00000177731 E052 5.2789811 0.0028524726 0.111979378 0.38696376 17 18252472 18252492 21 - 0.878 0.697 -0.722
ENSG00000177731 E053 9.3276978 0.0131194789 0.535909969 0.80245160 17 18252493 18252556 64 - 0.982 1.044 0.229
ENSG00000177731 E054 10.1455457 0.0107555456 0.869759533 0.95876188 17 18253301 18253356 56 - 1.039 1.054 0.055
ENSG00000177731 E055 8.8486157 0.0023979197 0.404403306 0.71469888 17 18253357 18253426 70 - 1.030 0.952 -0.291
ENSG00000177731 E056 5.3331465 0.0659500414 0.559570351 0.81587936 17 18253427 18253458 32 - 0.838 0.761 -0.302
ENSG00000177731 E057 0.6402162 0.0449613789 0.132043470 0.42115235 17 18253459 18253543 85 - 0.089 0.314 2.229
ENSG00000177731 E058 10.0274229 0.0014552021 0.782724150 0.92479942 17 18253544 18253598 55 - 1.030 1.054 0.088
ENSG00000177731 E059 15.2101675 0.0010871974 0.651239543 0.86349404 17 18253599 18253719 121 - 1.226 1.192 -0.119
ENSG00000177731 E060 1.7856111 0.0078493722 0.013716468 0.11417204 17 18253720 18253886 167 - 0.225 0.593 2.103
ENSG00000177731 E061 1.6725319 0.0659102327 0.008721828 0.08481535 17 18253887 18254078 192 - 0.162 0.593 2.688
ENSG00000177731 E062 6.2275140 0.0028362434 0.053794259 0.25899892 17 18254079 18254096 18 - 0.950 0.741 -0.813
ENSG00000177731 E063 10.2676942 0.0013035696 0.183331542 0.49635454 17 18254097 18254178 82 - 1.106 0.989 -0.427
ENSG00000177731 E064 5.9028285 0.0036577566 0.196630779 0.51352101 17 18254179 18254182 4 - 0.904 0.761 -0.555
ENSG00000177731 E065 13.2317075 0.0215263912 0.518663137 0.79184084 17 18254521 18254603 83 - 1.183 1.120 -0.225
ENSG00000177731 E066 7.8360218 0.0066203568 0.713872741 0.89390192 17 18254604 18254619 16 - 0.928 0.965 0.139
ENSG00000177731 E067 12.7539295 0.0106675911 0.548997780 0.81052130 17 18254620 18254682 63 - 1.163 1.111 -0.186
ENSG00000177731 E068 7.0641000 0.0559612121 0.825254301 0.94098524 17 18254769 18254790 22 - 0.916 0.897 -0.071
ENSG00000177731 E069 13.6984090 0.0778135246 0.526050520 0.79622268 17 18254791 18254854 64 - 1.202 1.129 -0.260
ENSG00000177731 E070 12.7356252 0.0318104907 0.565754978 0.81884609 17 18255183 18255263 81 - 1.170 1.102 -0.242
ENSG00000177731 E071 0.0000000       17 18256525 18256525 1 -      
ENSG00000177731 E072 9.7147932 0.0081639573 0.551348435 0.81151421 17 18256526 18256597 72 - 1.057 1.000 -0.207
ENSG00000177731 E073 0.1141751 0.0112636295 0.629137351   17 18256598 18256908 311 - 0.089 0.000 -10.906
ENSG00000177731 E074 14.2025256 0.0014844519 0.632427570 0.85330109 17 18256909 18257019 111 - 1.163 1.200 0.129
ENSG00000177731 E075 0.1315150 0.0122911935 0.458853496   17 18257020 18257033 14 - 0.000 0.102 10.476
ENSG00000177731 E076 0.1315150 0.0122911935 0.458853496   17 18257034 18257123 90 - 0.000 0.102 10.476
ENSG00000177731 E077 0.0000000       17 18257124 18257126 3 -      
ENSG00000177731 E078 0.2628107 0.0161027841 0.192756479   17 18257127 18257276 150 - 0.000 0.185 11.418
ENSG00000177731 E079 0.0000000       17 18258447 18258627 181 -      
ENSG00000177731 E080 6.7933014 0.0020718577 0.210868213 0.53211722 17 18258628 18258748 121 - 0.823 0.952 0.492

Help

Please Click HERE to learn more details about the results from DEXseq.