ENSG00000178199

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000458251 ENSG00000178199 No_inf pgwt_inf ZC3H12D protein_coding protein_coding 20.07 20.49386 18.16051 0.5874699 0.3417759 -0.1742968 1.120366 1.607713 0.5391229 0.5218718 0.1136573 -1.5587546 0.05439167 0.077275 0.029725 -0.047550 0.9928472467 0.0002706755 FALSE FALSE
ENST00000498662 ENSG00000178199 No_inf pgwt_inf ZC3H12D protein_coding protein_coding_CDS_not_defined 20.07 20.49386 18.16051 0.5874699 0.3417759 -0.1742968 1.598054 3.565611 0.0000000 0.3752669 0.0000000 -8.4820460 0.07635000 0.173525 0.000000 -0.173525 0.0002706755 0.0002706755 TRUE TRUE
MSTRG.25482.3 ENSG00000178199 No_inf pgwt_inf ZC3H12D protein_coding   20.07 20.49386 18.16051 0.5874699 0.3417759 -0.1742968 7.260313 7.019182 7.6317614 0.8409041 2.5828563 0.1205485 0.36516667 0.342200 0.422925 0.080725 1.0000000000 0.0002706755 FALSE TRUE
MSTRG.25482.4 ENSG00000178199 No_inf pgwt_inf ZC3H12D protein_coding   20.07 20.49386 18.16051 0.5874699 0.3417759 -0.1742968 9.370426 7.563581 9.2204080 0.8686649 2.7389372 0.2854188 0.46773333 0.370500 0.504475 0.133975 0.9928472467 0.0002706755 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000178199 E001 0.4897682 0.0159631907 0.97349079   6 149446795 149447470 676 - 0.174 0.172 -0.015
ENSG00000178199 E002 2.4879782 0.0185936999 0.43045643 0.73360975 6 149447471 149447654 184 - 0.473 0.594 0.570
ENSG00000178199 E003 3.7503566 0.0157711495 0.19090537 0.50570872 6 149447655 149447657 3 - 0.569 0.750 0.773
ENSG00000178199 E004 65.7100720 0.0081180264 0.37814372 0.69549727 6 149447658 149448045 388 - 1.794 1.846 0.175
ENSG00000178199 E005 55.2024770 0.0002742777 0.63759362 0.85594010 6 149448046 149448433 388 - 1.753 1.745 -0.028
ENSG00000178199 E006 281.2606817 0.0038086914 0.16447754 0.46945829 6 149448434 149451479 3046 - 2.431 2.465 0.112
ENSG00000178199 E007 3.8034177 0.0380159317 0.02653483 0.17172909 6 149452117 149452615 499 - 0.473 0.803 1.444
ENSG00000178199 E008 11.9701380 0.0212761577 0.52535185 0.79578440 6 149452616 149452722 107 - 1.140 1.086 -0.192
ENSG00000178199 E009 22.3734388 0.0046987311 0.06340171 0.28400499 6 149456666 149456900 235 - 1.425 1.311 -0.394
ENSG00000178199 E010 0.7524321 0.0142242207 0.43743079 0.73910753 6 149459524 149459678 155 - 0.174 0.295 0.985
ENSG00000178199 E011 0.7194810 0.0144972603 0.39142533 0.70504904 6 149461668 149461830 163 - 0.298 0.172 -1.015
ENSG00000178199 E012 14.7174442 0.0102849553 0.01019024 0.09386765 6 149461831 149461970 140 - 1.295 1.086 -0.740
ENSG00000178199 E013 26.4513314 0.0005409436 0.08969856 0.34377011 6 149474239 149474613 375 - 1.481 1.396 -0.296
ENSG00000178199 E014 0.8503358 0.0143783713 0.67646565 0.87544380 6 149483051 149483175 125 - 0.298 0.238 -0.430
ENSG00000178199 E015 5.8416091 0.0467915922 0.45803980 0.75309444 6 149484813 149485012 200 - 0.884 0.786 -0.379
ENSG00000178199 E016 0.0000000       6 149485013 149485014 2 -      
ENSG00000178199 E017 0.3417870 0.0246389570 0.09806553   6 149485122 149485293 172 - 0.240 0.000 -11.908
ENSG00000178199 E018 0.1145948 0.0112309897 0.52035405   6 149485376 149485423 48 - 0.096 0.000 -10.516

Help

Please Click HERE to learn more details about the results from DEXseq.