ENSG00000178691

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000322652 ENSG00000178691 No_inf pgwt_inf SUZ12 protein_coding protein_coding 25.29699 22.68197 24.12196 0.3918347 0.5577778 0.08876302 3.335678 2.638029 3.259013 0.5993530 0.6152138 0.3039362 0.1309667 0.116375 0.134775 0.018400 9.984969e-01 3.500941e-07 FALSE TRUE
ENST00000578106 ENSG00000178691 No_inf pgwt_inf SUZ12 protein_coding retained_intron 25.29699 22.68197 24.12196 0.3918347 0.5577778 0.08876302 4.217230 7.972619 0.000000 0.5870238 0.0000000 -9.6407184 0.1695167 0.350475 0.000000 -0.350475 3.500941e-07 3.500941e-07 FALSE TRUE
ENST00000580398 ENSG00000178691 No_inf pgwt_inf SUZ12 protein_coding protein_coding 25.29699 22.68197 24.12196 0.3918347 0.5577778 0.08876302 1.764261 1.940274 2.135989 0.8891886 1.3356607 0.1379659 0.0728250 0.086625 0.091100 0.004475 9.928472e-01 3.500941e-07 FALSE TRUE
MSTRG.12444.2 ENSG00000178691 No_inf pgwt_inf SUZ12 protein_coding   25.29699 22.68197 24.12196 0.3918347 0.5577778 0.08876302 15.870549 9.972279 18.618094 0.4070067 1.9764973 0.9000389 0.6220833 0.439475 0.769450 0.329975 5.302821e-01 3.500941e-07 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000178691 E001 0.2462566 1.641675e-02 8.898678e-01   17 31937007 31937040 34 + 0.088 0.103 0.243
ENSG00000178691 E002 0.6230956 1.448537e-02 5.204909e-01   17 31937041 31937066 26 + 0.161 0.255 0.828
ENSG00000178691 E003 1.3254488 1.057803e-02 5.429833e-01 8.069199e-01 17 31937067 31937173 107 + 0.411 0.315 -0.564
ENSG00000178691 E004 6.4104126 1.419530e-02 4.186369e-01 7.249747e-01 17 31937174 31937433 260 + 0.914 0.819 -0.365
ENSG00000178691 E005 6.8556818 8.118240e-02 2.667731e-01 5.950886e-01 17 31937434 31937520 87 + 0.970 0.801 -0.645
ENSG00000178691 E006 7.0654273 9.412121e-02 1.882043e-01 5.025226e-01 17 31940286 31940332 47 + 1.000 0.783 -0.831
ENSG00000178691 E007 6.6230821 4.936602e-03 1.792144e-01 4.915411e-01 17 31940422 31940486 65 + 0.948 0.801 -0.564
ENSG00000178691 E008 3.5594500 5.175672e-02 7.133566e-02 3.031723e-01 17 31947617 31947685 69 + 0.775 0.496 -1.216
ENSG00000178691 E009 0.2448134 1.676486e-02 8.907040e-01   17 31965695 31966146 452 + 0.088 0.103 0.243
ENSG00000178691 E010 6.1280870 2.322232e-03 1.401300e-01 4.333389e-01 17 31966147 31966196 50 + 0.926 0.763 -0.631
ENSG00000178691 E011 0.2461098 1.656006e-02 8.895392e-01   17 31966197 31967589 1393 + 0.088 0.103 0.243
ENSG00000178691 E012 7.6977323 1.767365e-03 1.211964e-01 4.027187e-01 17 31973146 31973231 86 + 1.010 0.853 -0.591
ENSG00000178691 E013 27.6001909 5.280068e-04 1.086492e-01 3.804947e-01 17 31975482 31975713 232 + 1.500 1.407 -0.321
ENSG00000178691 E014 11.1024864 1.248005e-03 1.467545e-01 4.429501e-01 17 31976521 31976614 94 + 1.141 1.014 -0.460
ENSG00000178691 E015 9.6116952 1.925897e-02 1.059527e-01 3.758615e-01 17 31982999 31983104 106 + 1.104 0.927 -0.650
ENSG00000178691 E016 29.3175058 1.367528e-03 7.810423e-04 1.484512e-02 17 31988320 31988497 178 + 1.566 1.374 -0.660
ENSG00000178691 E017 18.9942612 1.570676e-02 7.939220e-01 9.290239e-01 17 31993242 31993333 92 + 1.313 1.287 -0.091
ENSG00000178691 E018 22.9346348 8.002248e-04 9.610884e-01 9.907247e-01 17 31993865 31994008 144 + 1.379 1.379 -0.003
ENSG00000178691 E019 0.0000000       17 31994353 31994563 211 +      
ENSG00000178691 E020 23.3282181 6.247405e-04 8.085222e-02 3.249142e-01 17 31994564 31994721 158 + 1.437 1.327 -0.379
ENSG00000178691 E021 36.1441788 4.858531e-03 5.864787e-02 2.718024e-01 17 31995564 31995762 199 + 1.620 1.511 -0.374
ENSG00000178691 E022 19.8191269 7.500403e-04 6.060377e-01 8.405298e-01 17 31996798 31996877 80 + 1.337 1.299 -0.131
ENSG00000178691 E023 315.9758566 6.967963e-05 4.382181e-14 8.162542e-12 17 31998658 32001038 2381 + 2.459 2.541 0.273

Help

Please Click HERE to learn more details about the results from DEXseq.